Angewandte Chemie International Edition
Articles in this Issue
Small‐Molecule Probes Enhance in Vivo Field‐Effect Transistor‐Based Biosensing by Overcoming Debye Length Limitations
Abstract Field‐effect transistor (FET) biosensors have garnered extensive interest in biomedical detection, while their high sensitivity is maintained only when...
Polymer‐Templated In Situ Growth of Centimeter‐Scale Perovskite Nanocrystal Arrays with Ultrasmall Pixel Size and High Stability
Abstract Miniaturizing the perovskite nanocrystal (PNC) pattern is critical for advancing integrated chip‐level devices and next‐generation displays. However, scalable fabrication of...
Engineering Proton Clamp Traps in Covalent Organic Frameworks for Boosting CO <sub>2</sub> Capture and Photoreduction
Abstract The targeted construction of efficient CO 2 capture platforms for photocatalysis remains a significant challenge...
Photoresponsive Hexaarylbiimidazole‐Crosslinked Hydrogels: From Synthesis to Diverse Applications
Abstract The development of light‐sensitive hydrogels with rapid and on‐demand responses stands represents an important outstanding challenge for developing flexible devices. Here, a...
Stable Four‐Electron Zinc‐Iodine Battery Realized by Polyacrylamide as Catalytic Binder
Abstract Realizing stable four‐electron reactions () is the key to boosting the energy density of aqueous zinc‐iodine batteries (ZIBs). In most of the traditiona...
A Family of Cobalt(II) Complexes Exhibiting Record Dissymmetry Factors in Vibrational Circular Dichroism
Abstract A family of novel chiral cobalt(II) complexes with two diketonate and one bis(oxazoline) ligand, [Co(dkt) 2 (BOX...
Divergent Ring‐Opening Functionalization and Reductive Coupling of Pyridines via Zirconium Alkylidene Complexes
Abstract The transformation of N‐heterocycles such as pyridines is of fundamental and practical importance, yet direct cleavage of their aromatic C─N bonds remai...
Inside Front Cover: Topological Duality: Constructing High‐Nuclearity Metal Clusters with Unleashed Active Sites for Efficient and Durable CO <sub>2</sub> Electroreduction (Angew. Chem. Int. Ed. 52/2025)
Sparingly Solvating Electrolyte with Hofmeister Selectivity for Practical Long‐Lived Li–Se Batteries
Abstract The excessive solvation of lithium polyselenides (LiPSe), which are highly nucleophilic, in organic electrolytes is one of the most critical challenges...
Tailoring Spin–Spin Dipolar Interactions by Conformational Locking Toward Room‐Temperature Molecular Qubits
Abstract Chichibabin's hydrocarbons (CHs) typically exhibit resonance equilibrium between closed‐shell quinoidal and open‐shell diradical configurations due to t...
Fluorescence Visualization of Helix Inversion in Biomimic Polymeric Foldamer
Abstract Biomacromolecules such as DNA, proteins, and polysaccharides possess unique helical structures that are closely related to their biological functions in...
Heteromultivalent Nanogels as Highly Potent Inhibitors of <i>Pseudomonas Aeruginosa</i>
Abstract The increasing prevalence of microbial resistance requires new antibacterial concepts for selective targeting and killing of pathogenic bacteria. Here,...
Ultralow‐Lattice‐Mismatched Near‐Zero‐Strain Zn (0002) Anodes for Stable Zinc Metal Batteries
Abstract Compared with (100) and (101) planes, Zn (0002) plane with the lowest nucleation energy is optimal for practical rechargeable zinc metal batteries (ZMBs...
Uncovering the Electrochemical Origin of Alkalization in Viologen‐Based Aqueous Flow Batteries
Abstract Alkalization of viologen‐based anolytes during charge–discharge cycling poses a formidable obstacle to the practical implementation of aqueous organic redox flow batteries (...
Photoexcitation‐Induced Chiral Self‐Assembly for Phosphorescence‐to‐Thermally Activated Delayed Fluorescence Transformation
Abstract Phosphorescence and thermally activated delayed fluorescence are currently two important photophysical pathways that have greatly promoted the development of display, sensin...
Structure Model‐Guided Reprogramming Enables Functional Interconversion of Phomactatriene and Verticillene Synthases
Abstract Terpenoids represent the most structurally diverse class of natural products on Earth. Terpene synthases are key enzymes for constructing the complex and varied terpene skel...
Decoding Molecular Conformations of Dimeric Non‐Fullerene Acceptors for High‐Sensitivity Near‐Infrared Organic Photodetectors
Abstract The molecular conformation and packing behavior of dimeric non‐fullerene acceptors (NFAs) remain largely unexplored, limiting their rational design for...
Outside Back Cover: Optical Switching of Catalytic Pathways for Hydrogen Generation via Light‐Handedness Control on Chiral Nanostructures (Angew. Chem. Int. Ed. 52/2025)
In Situ Crosslinked Self‐Assembled Monolayer as Processing Stable Hole Selective Contact in Perovskite Solar Cells
Abstract Self‐assembled monolayers (SAMs) have demonstrated remarkable potential in advancing the efficiency and operational stability of p‐i‐n structured perovs...
Disulfide‐Initiated Addition–Fragmentation Chain Transfer in Allyl Sulfide‐Based Vitrimers
Abstract Covalent adaptable networks (CANs) have emerged as a promising class of materials that incorporate dynamic covalent bonds, enabling reprocessability and...
Built‐In Electric Field Triggered Interfacial Water Activation for Industrial‐Level Electrosynthesis of Ethylene from CO <sub>2</sub>
Abstract The electrochemical reduction of CO 2 to ethylene (C 2 H...
Layered Double Hydroxides as Building Blocks for Precise Catalysis
Abstract Layered double hydroxides (LDHs) are structurally tunable, 2D materials that serve as versatile precursors for the design of heterogeneous catalysts. Th...
A Smart Self‐Immobilization Magnetic Resonance Contrast Agent for Delayed Tumor Imaging In Vivo
Abstract Achieving tumor‐specific accumulation and high relaxivity remains critical yet challenging for improving magnetic resonance imaging (MRI) probe sensitiv...
Linker Enantiomericity Engineering in Reticular Frameworks for Architecting Robust Materials with Synergetic Open Metal Sites for Efficient SF <sub>6</sub> Capture
Abstract Chiral linkers offer built‐in enantiomericity capable of regulating pore microenvironments or even net dimensions and topologies of the resulting reticu...
Intact Mass Profiling Reveals Phospho‐Proteoforms of the Catenins (85–110 kDa) Regulated by Actomyosin Contractility
Abstract A central challenge in top‐down proteomics (TDP) is the characterization of large proteoforms (>70 kDa) due to their high spectral complexity in mass...