Angewandte Chemie International Edition
Articles in this Issue
Physicochemically Informed Axial Chirality Descriptors Enable Accurate Prediction of Atropisomeric Stability
Abstract Atropisomers play a vital role in asymmetric synthesis, drug discovery, and the development of functional materials. However, the rational design of atr...
Inside Front Cover: Some Like It Hot –Structural Changes in Extremophile Rubredoxin at 120 °C (Angew. Chem. Int. Ed. 5/2026)
B‐N Fused Anthracene as Functional Linker for π‐Extended Viologens: Near‐IR Emission and Electrochromism
Abstract As prototypical organic electrochromic materials viologens have been extensively studied in display technologies, smart materials, and energy storage ap...
Unlocking Selective Electrochemical Regulation via Interlayer Anion Competition for Nitrate Extraction from Wastewater
Abstract Electrochemical separation technology offers an effective approach to recycle valuable nitrogen from industrial wastewater, but its separation efficienc...
Spatially Orchestrated Oxygen Motifs Decouple Ion Dissociation/Migration in Liquid Crystal Elastomer for High‐ Performance Solid‐State Li Metal Batteries
Abstract Solid polymer electrolytes (SPEs) emerge as prime candidates for next‐generation solid‐state lithium metal batteries, capitalizing on their intrinsic el...
A Structure‐Defined Cu(I) Dual‐Atom Catalyst with a Cu <sub>2</sub> N <sub>6</sub> Motif in a Metal‐Organic Framework for CO Electroreduction
Abstract The electroreduction of carbon monoxide (CO) provides a sustainable pathway to valuable multi‐carbon (C 2+ ) pro...
Skeletal Editing of Hydroxyl Oxindoles via Organoiodine‐Catalyzed Oxygen Atom Insertion Reaction
Abstract In the field of skeleton editing, the development of catalytic single‐atom insertion into five‐membered rings is highly desirable and holds significant...
Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres
Abstract Molecular scaffolds with a high fraction of sp 3...
Regulating *H Dynamics via Photoinduced Oxygen Vacancy‐Lattice Oxygen Frustrated Lewis Pairs for Superior CO <sub>2</sub> Photoreduction
Abstract Herein, we construct photoinduced oxygen vacancy‐lattice oxygen frustrated Lewis pairs (V o ‐O...
Unveiling Residual Charge Effects in the Direct Regeneration of Spent LiFePO <sub>4</sub>
Abstract The emergence of safe crushing technologies for spent lithium‐ion batteries treatment will significantly increase the proportion of incompletely dischar...
Near‐Infrared Light‐Activated Circular Oligonucleotides for Spatiotemporal Control of Gene Silencing in Mice
Abstract Oligonucleotide therapeutics hold great promise for gene regulation but face challenges in achieving spatiotemporal control of their functions in vivo. In this study we deve...
Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Abstract Thiophenes and their saturated analogues are versatile C 4 ‐building blocks used to construct structurally intri...
Organoplatinum(II) J‐Aggregates with Prolonged Triplet Lifetimes for Enhanced Photodynamic and Photocatalytic Therapy
Abstract J‐aggregates have demonstrated superior phototherapeutic performance compared to their monomeric counterparts. However, the underlying mechanisms for th...
Interwoven Porous ZIF Polyhedra Threaded with Silver Thiolate Nanowires for Ultrasensitive SERS Detection of Chlorotoluene Isomers
Abstract The identification of isomeric organic compounds poses a significant challenge due to their structurally and chemically analogous features. This researc...
O <sub>2</sub> Activation at an Enzymatic Diiron Site: Bridging Ligand Substitutions Alter Diferric‐(Hydro)peroxo States
Abstract A variety of non‐heme diiron enzymes employ a conserved 2‐His‐4‐carboxylate motif to coordinate a dinuclear Fe site and activate dioxygen for diverse ty...
Enantioselective Synthesis of Chiral Sulfinamidines via Asymmetric Amination of Sulfenamides Using a Chiral Phosphoric Acid Catalyst
Abstract Despite the significant applications of stereogenic‐at‐sulfur compounds in pharmaceutical sciences and organic chemistry, efficient methods for precise construction of valua...
Highly Stable Twin Defects Enabled by High Entropy Configuration
Abstract The strategic engineering of crystalline defects has been proven effective in enhancing the efficiency of metallic catalysts. However, owing to the confined and metastable n...
Dynamic Li <sup>+</sup> Respiration Effect Enables Cascade Conversion of Lithium Polysulfides for Li–S Batteries
Abstract High‐energy‐density lithium–sulfur batteries exhibit obvious kinetics differences involving multistep reactions, making it hard to realize constantly hi...
Facile Introduction of Quantum Confinement in Linear Conjugated Polymers for Photocatalytic Hydrogen Evolution
Abstract While the structurally tunable nature of Linear conjugated polymers (Linear CPs) offers promising opportunities for advancing photocatalysts, their curr...
Cross‐Shaped Donor‐π‐Acceptor Covalent Organic Frameworks with Tunable Push–Pull Architectures for Effective Photocatalytic H <sub>2</sub> O <sub>2</sub> Production
Abstract Efficient photocatalysts for H 2 O 2 production are pivotal for solar‐to...
Biocatalytic Atroposelective Synthesis of Axially Chiral Styrenes via Dynamic Kinetic Resolution
Abstract Enzymatic synthesis of atropisomers has recently attracted considerable research attention, with most studies focusing on axially chiral biaryls. We report a less explored a...
Excited State Modulation of Copper Clusters Realized by Single‐Site Alteration Achieving Near‐Infrared Luminescence
Abstract Modulating the excited states of coinage metal clusters can effectively improve their photophysical properties, and significant progress has been realiz...
Atomic‐Scale Structural Distortion Drives Exciton Localization for Near‐Unity Photoluminescence in Copper–Iodide Clusters
Abstract Engineering structural distortions presents a powerful strategy for tailoring the optoelectronic properties of luminescent materials, while a fundamenta...
Sequential Phase‐Engineered Afterglow Modulation in Mn‐Doped Cs‐Cd‐Cl Perovskites for X‐ray Time‐Lapse Flexible Imaging
Abstract X‐ray time‐lapse flexible imaging and information retrieval significantly broaden the application scope of X‐ray technologies, while posing new challeng...
Atomic Fe‒P Pairs Eliminate H <sub>2</sub> O <sub>2</sub> Migration Barriers for Sustainable Electro‐Fenton Water Treatment
Abstract The electro‐Fenton process, involving O 2 reduction to H 2 O...