Angewandte Chemie International Edition
Articles in this Issue
Dual‐Channel Fluorescence Assays with Supramolecular Host‐Dye Reporter Pairs for Membrane Activity Mapping of Peptides
Abstract Membrane‐active peptides (MAPs) are a major class of peptides that renders lipid bilayer membranes permeable for hydrophilic compounds. MAPs include cel...
Photoactive Luminescence in a Silver Cluster Crystal
Abstract Due to their atomically precise structures and tunable electronic properties, coinage metal clusters have emerged as a significant class of luminescent...
Breaking the Trade‐Off Between Activity and Stability in Reverse Water–Gas Shift Reaction by Forming Highly Active Pt─O─Na─Si Unit Within Silicalite‐1 Catalyst
Abstract The reverse water gas shift (RWGS) reaction holds significant industrial importance. While directly incorporating alkali metals can enhance the catalyti...
All‐Scale Structural Optimization of Resiliently Crystalline Na–Ce–Sn–S Chalcogel for Efficient Oxygen Evolution Reaction Electrocatalyst
Abstract The metal cation linker in metathesis‐derived chalcogels critically governs structural evolution, porosity, and resultant physicochemical properties. Ho...
Some Like It Hot –Structural Changes in Extremophile Rubredoxin at 120 °C
Abstract How does the structure of a protein change as the temperature is raised from cryogenic conditions at 100 K to 393 K? Understanding the structure and dyn...
Possible Peierls Distortion Through Re <sub>2</sub> Dimer Formation in the LaNiO <sub>2</sub> ‐Type Nitrides <i>Ln</i> ReN <sub>2</sub> ( <i>Ln</i> = Pr, Nd)
Abstract Nitride perovskites are a recently opened class of materials with a limited number of stable compounds. Notably, anion‐vacancy‐ordered materials such as...
Minimalist Molecules Drive Liquid–Liquid Phase Separation to Modularly Assemble Functional Coacervate Protocells
Abstract Although coacervates formed via liquid–liquid phase separation (LLPS) are widely considered plausible protocell models relevant to the origin of life, i...
Migratory C(sp <sup>2</sup> )–H/C(sp <sup>3</sup> )–H Cross‐Coupling Enabled by Metallaphotoredox Catalysis
Abstract Direct twofold C─H cross‐coupling between two readily available substrates offers a step‐ and atom‐economical alternative to traditional cross‐coupling reactions. Here we re...
Supramolecular Mechanoluminescence via Fluorine Interactions
Abstract Mechanoluminescent (ML) materials, capable of converting mechanical stimuli directly into light emission without external excitation, hold great potenti...
Molecular Traffic Control: Fast Mg <sup>2+</sup> Transport via Carbonyl‐Induced Ion‐Dipole Interactions in Covalent Organic Framework Channels
Abstract Rechargeable magnesium batteries (RMBs) have garnered significant attention due to their high energy density, abundant resources, and inherent safety. H...
Confined Chiral Center Stacking Induced Twisted Silica Nanoribbons for Tumor Cell Proliferation Regulation
Abstract Chirality governs physiological processes across scales, yet the ambiguous link between molecular chirality and mesostructured chirality persists. Here, we show that while p...
<i>C</i> ‐Glycosyl α‐Amino Acids as Structural Encoders of Peptide Conformation
Abstract C ‐glycosylation is a well‐established strategy for improving the pharmacokinetic properties of peptides; however, the influence of...
Near‐Infrared Triggered Anion Transport Induces Cancer Cell Death
Abstract Artificial transmembrane anion carriers have shown potential in biological research and medicine, such as chemotherapeutics to treat channelopathies and anticancer agents. S...
Aminoboranes as Rationally Tuned Organic Photosensitizers for Energy Transfer Catalysis
Abstract We report a new class of rationally designed organic photosensitizers based on boron–nitrogen‐substituted scaffolds, capable of mediating challenging tr...
Hydroxyl Radicals Unlock Strong C( <i>sp</i> <i> <sup>3</sup> </i> )─Si Bonds: Photocatalytic Alkylation and Silacycle Engineering
Abstract Organosilicon reagents play a significant role in the preparation of molecules essential to synthetic chemistry, materials science, and medicinal chemis...
Unveiling Anion‐Cation Interaction of Electrolyte for Long‐Life Ah‐Level Aqueous Zinc Metal Batteries
Abstract Aqueous zinc metal batteries (AZMBs) are attractive for stationary energy storage due to their low cost and high safety. However, parasitic side reactio...
Three‐Motif Molecular Junction with Long‐Lived Charge Carriers for Efficient Overall Photosynthesis of H <sub>2</sub> O <sub>2</sub>
Abstract Photosynthesis of hydrogen peroxide (H 2 O 2 ) from air and water has em...
Low‐Valent Single‐Atom Indium Site Regulating Ionic Interference and Adsorbed Hydrogen for Near‐Unity Electrosynthesis of Ammonia
Abstract Microenvironment modulation, involving the selective adsorption of ions and the engineering of hydrogen radicals, is critical for the neutral electroche...
Triptycene‐Derived 3D‐Architectured Non‐fullerene Acceptor with High Luminescence Enables 20.26% Efficiency Organic Solar Cells
Abstract Developing narrow‐bandgap nonfullerene acceptors (NFAs) with high photoluminescence quantum yield (PLQY) is a major challenge, but also a promising strategy to reduce nonrad...
Nanoclusters as Deep‐Red Light‐Absorbing Photocatalysts for Laser‐ or LED‐Driven Povarov Cyclization
Abstract Photocatalysis is primarily initiated with ultraviolet/blue light, which has several drawbacks, namely, deficiencies in reaction efficiency, and scalabi...
Dual‐Stabilization Strategy for Inhibiting Metal Nanoparticle Sintering Over Ceria Surfaces
Abstract Ceria supported noble metals are important commercial catalysts, however, the long‐term stability suffering from metal particle sintering still challeng...
Enriching Higher Affinity Aptamers by Addressing the Kinetic Aspect of the DNA Strand‐Displacement Reaction
Abstract Selection of high affinity aptamers is the basis for aptamer‐related applications. Most aptamer selections prioritize thermodynamic factors such as the...
Patching Solid Electrolyte Interphase via Modulating Anion Decomposition Reactions for Stable Lithium Metal Batteries
Abstract Solid electrolyte interphase (SEI) on lithium (Li) metal anodes undergoes repeated rupture and patching during cycles, which induces the formation of in...
Esterase‐Responsive Mitochondria‐Targeted Hydropersulfide Donors Mitigate Doxorubicin Cardiotoxicity While Preserving Anticancer Activity
Abstract Therapeutic agents that protect the heart from doxorubicin (DOX) toxicity without reducing its anticancer efficacy remain a critical unmet need. We repo...
Creep Resistant and Reprocessable Polyamide Networks Based on Reversible Lactone Ring‐Opening
Abstract Amides are robust chemical linkages of interest in the field of dynamic covalent polymer networks (DCPNs), but their activation towards dynamic exchange remains an outstandi...