Angewandte Chemie International Edition
Articles in this Issue
Synergistic Engineering of Bulk Integrity and Interfacial Reversibility via a Hierarchical Triphase Matrix for Stable Na Metal Batteries
ABSTRACT Considerable volume fluctuation and sluggish Na + diffusion capability have been identified as the key factors t...
Ligand‐Controlled Switchable Synthesis of Fused Polycycles by Selective 1,4‐Palladium Migration
ABSTRACT The palladium migration strategy has been employed for the functionalization of remote C─H bonds, offering an efficient approach to construct fused heterocycles. In this stu...
Wafer‐Scale MgO:Li <sup>+</sup> ,Cr <sup>3+</sup> Transparent Ceramic Scintillators With NIR Emission for X‐Ray Dual‐Mode Fusion and Time‐Lapse Imaging
ABSTRACT The integration of X‐ray and near‐infrared (NIR) imaging holds great potential for nondestructive detection and biomedical analysis. However, premature...
Isostructural Transformation From a Hydrogen‐Bonded Metal‐Complex Framework to a Metal–Organic Framework for Enhanced Ammonia Tolerance
ABSTRACT Metal–organic frameworks (MOFs) are promising sorbents for ammonia (NH 3 ) storage and capture. However, rationa...
Lattice Hydroxyl‐Assisted Platinum Single Atom Catalyst Toward Hydrogen Production From Methanol Aqueous Reforming
ABSTRACT Methanol aqueous reforming reaction (APRM) provides a green and clean route towards hydrogen production, in which the structure design and preparation o...
Programmable Diacetylene‐Bridged Cyclotetrathiophenes With Nonplanar π‐Expanded Skeleton for Electrochemical Sodium Storage
ABSTRACT Fused aromatic ring systems offer flexibility in molecular‐level design, facilitating programmable redox activity and exhibiting remarkable energy‐stora...
Dithioketal Polymers Via Radical Polymerization of γ‐Dithiobutyrolactone
ABSTRACT Polymers bearing in‐chain dithioketal groups are an emerging class of materials with specific properties like reactive oxygen species (ROS)‐responsiveness and vitrimer‐type...
Unveiling Volcano‐Type Trends in SOCT‐ISC Photosensitization: Energy Gap Law‐Guided Strategy for Efficient Photodynamic Therapy
ABSTRACT The development of high‐performance heavy‐atom‐free photosensitizers requires deep insight into their excited‐state dynamics. We report a series of cyan...
Enantioselective Total Synthesis of Breviones Utilizing a Bio‐Inspired Skeletal Editing Strategy
ABSTRACT Inspired by skeletal editing transformations in the biosynthesis of spiro diterpene pyrones, we herein present an enantioselective total synthesis of th...
Charge‐Tunable Dense Dual‐Atom Nanozymes Reprogram Biothiol Metabolism Through Multi‐Enzyme‐Mimetic Catalysis to Synergistically Induce Ferroptosis and Disulfidptosis
ABSTRACT Biothiols play a pivotal role in maintaining cellular redox homeostasis, coordinating programmed cell death pathways, and modulating immune responses. Reprogramming biothiol...
Stimuli‐Responsive Silsesquioxane Nanozymes for Organocatalysis in Water and Prodrug Activation in Cells
ABSTRACT Synthetic nanozymes have emerged as promising alternatives to natural enzymes for catalytic and therapeutic applications, yet their limited stability, aqueous compatibility,...
4‐Dimethylaminophenol: A ‘Smaller’‐Molecule PPI Inhibitor Targeting the PSD95 GK Domain Against Ischemic Stroke
ABSTRACT Protein–protein interactions (PPIs) represent challenging yet promising therapeutic targets. This study identifies 4‐dimethylaminophenol, an ultralow molecular weight compou...
Electrostatic Potential Tuning‐Driven Molecular Rotor Rotation in Isostructural Metal‐Organic Frameworks for C <sub>3</sub> H <sub>6</sub> /C <sub>3</sub> H <sub>8</sub> Separation
ABSTRACT C 3 hydrocarbon separation is a core process for refining high‐value‐added petrochemical products. However, due...
Selective Oxidation of Tertiary Silanes Enabled by Tandem Single Atom Cerium Catalyzed Water Splitting/Non‐Bonding Phosphorus Site Promoted Nucleophilic Substitution
ABSTRACT The utilization of heterogeneous catalysts, particularly single‐atom catalysts (SACs), to mimic or even supplant their homogeneous counterparts for building complex molecula...
RaPID Selection of Backbone Macrocyclic Peptides Targeting Akt2
ABSTRACT Backbone‐cyclic peptides (BMPs) are an attractive class of molecules appeared in diverse natural bioactive products. However, mRNA display technology co...
Amorphous/Crystalline Heterojunction Ni(OH) <sub>2</sub> /Cu <sub>2</sub> O(111) for Photoelectrocatalysis NO <sub>3</sub> <sup>−</sup> ‐to‐NH <sub>3</sub> : Positive Onset Potential, High Selectivity, and Complete Conversion
ABSTRACT Photoelectrocatalytic selective nitrate (NO 3 − ) reduction to ammonia (NH...
Wide‐Range Color‐Tunable Narrowband Fluorescence Emitters Based on 1,2‐BN‐Embedded Polycyclic Aromatic Hydrocarbons
ABSTRACT Developing a generalizable design principle that reconciles wide‐range color tunability with intrinsically narrowband emission in polycyclic aromatic hy...
Solvation‐Mediated Free Energy Stabilization Enables Li/CF <sub>x</sub> Pouch Cells Over 800 Wh kg <sup>−1</sup> via Minimizing Heat Dissipation
ABSTRACT Maximizing electrochemical energy conversion efficiency requires minimizing parasitic heat release. Li/CF x batt...
Isoreticular Modulation of Electrical Conduction and Magnetic Properties in Semiconducting Lanthanide‐based Metal−Organic Frameworks
ABSTRACT The integration of tunable magnetic properties and electrical conductivity within a single material presents significant opportunities for spintronic ap...
Selective Glycine Electrosynthesis via C‐N Coupling Enabled by Synergistic Mott–Schottky Heterojunction and Oxygen Vacancies
ABSTRACT Glycine, an indispensable amino acid essential for diverse biological processes, remains challenging to synthesize directly via electrosynthesis from si...
Cyclobenzoin Macrocycles: Guest Capture and Applications in Energy Technologies
ABSTRACT Cyclobenzoins are organic macrocycles prepared by the benzoin condensation of aromatic dialdehydes. These compounds are easily derivatized into close to...
One‐Pot Synthesis of Twisted Helical and Quasi‐Planar Boron‐Nitrogen Doped Polycyclic Aromatic Hydrocarbons for Narrowband Electroluminescence
ABSTRACT Heteroatom‐doped polycyclic aromatic hydrocarbons (PAHs) with special topological structures have garnered significant attention owing to the effective...
Engineering of Lewis Acid Sites in Mesoporous Zeolite Achieves Record Fructose Yield of 71.5% for Glucose Isomerization in Ethanol
ABSTRACT Lewis acid catalyzed glucose isomerization is a vital step in biorefinery, but it's restricted by the limited catalytic toolkit and reaction equilibrium. Herein, we report t...
Inside Back Cover: Catalysis AI Agent Guides Discovering the Universal Design Principle of Cu‐Based Single‐Atom Alloy Catalysts for CO <sub>2</sub> Electroreduction (Angew. Chem. Int. Ed. 21/2026)
Sustainable Aqueous Zn‐ion Batteries: Green Materials, Low‐Carbon Manufacturing, and Circular Economy
ABSTRACT Sustainable aqueous zinc‐ion batteries (AZIBs) have emerged as promising next‐generation energy storage solutions, aligning with global initiatives to mitigate climate chang...