Angewandte Chemie International Edition
Articles in this Issue
Molecular‐Level π‐Stacking Engineering in Dative B←N Frameworks for Superior Photocatalytic H <sub>2</sub> O <sub>2</sub> Production
ABSTRACT The photocatalytic synthesis of hydrogen peroxide (H 2 O 2 ) from O...
Dual‐Interface Nanopore Array Sensor Revealing the Synergistic Oscillations of Lactate Efflux in Cancer Cells
ABSTRACT Lactate is a key substrate and signaling molecule in tumor metabolism. Its efflux from cancer cells acidifies the tumor microenvironment and reflects the energy metabolic st...
Hydrogen‐Bond‐Networked Robust Binder Enabling Long‐Cycling Sulfide‐Based All‐Solid‐State Lithium Batteries
ABSTRACT Wet processing is promising for scalable manufacture of sulfide‐based all‐solid‐state lithium batteries (ASSBs), but it demands binders compatible with...
Hydrogen‐Bond Anchored Channel‐Microenvironment Engineering in Polymer Membranes for Efficient Lithium Extraction
ABSTRACT The creation of synthetic membranes that mimic the high selectivity and flux of biological ion channels remains a major challenge in separation science....
Controllable Electrocatalytic Synthesis of Aldehydes From Alcohols on Co‐Based Catalysts: A Redox Cycling‐Mediated Indirect Oxidation Mechanism
ABSTRACT The electrocatalytic oxidation of biomass‐derived alcohols offers a green and sustainable route for the preparation of aldehydes, which, however, still...
Synergistic Dynamic Hydrogen‐Bond Engineering in COF Cathode and Hydrogel Electrolyte for Durable NH <sub>4</sub> <sup>+</sup> Storage
ABSTRACT Aqueous ammonium‐ion batteries (AAIBs) have garnered considerable attention for sustainable energy storage, leveraging the rapid diffusion kinetics of N...
Palladium‐Doping‐Enabled Interface Synergy for Superb Ampere Level Ammonia Electrosynthesis From Nitrate
ABSTRACT The practical electrocatalytic nitrate‐to‐ammonia conversion suffers from insufficient performance at industrial current densities. Here, we report an e...
Palladium‐Catalyzed Three‐Component Coupling Through Carbene Migratory Insertion: Access to Allenes and 1,5‐Enynes
ABSTRACT Palladium‐catalyzed cross‐coupling reactions of propargylic electrophiles with carbon nucleophiles have been established as straightforward and reliable methods for the synt...
Palladium‐Catalyzed Carbonylative Alternating Copolymerization of Alkynols and Carbon Monoxide
ABSTRACT Conventional methods for polyester synthesis offer limited control over stereochemistry and exhibit constrained functional group tolerance, restricting...
A Scalable, Direct‐to‐Biology Platform for Accelerated Discovery of Cereblon‐Based Molecular Glue Degraders
ABSTRACT Molecular glue degraders (MGDs) offer transformative potential for expanding the druggable proteome; however, their discovery is severely impeded by mechanistic complexities...
An Oxygen Self‐Sufficient Nanozyme Engineered From Metal–Organic Cage for Dual‐Modal Self‐Reporting Theranostics
ABSTRACT The development of intelligent theranostic platforms capable of improving tumor‐hypoxic microenvironment and self‐reporting therapeutic status is crucia...
2‐Azaazulenium Hemicyanine Dyes for NIR‐II Multimodal Imaging and Combined Phototherapy
ABSTRACT Hemicyanine dyes are well‐defined donor–π–acceptor molecules whose photophysical and biological properties can be precisely tuned through rational molec...
Anti‐Heavy‐Atom Effect Boosts Electroluminescence in Copper Cluster‐Based LEDs
ABSTRACT The heavy‐atom effect plays a pivotal role in promoting intersystem crossing and enhancing phosphorescence. However, its impact on electroluminescence i...
Shoupeng Cao
The Importance of Ligand Coverage on Nanocatalysis: Optimizing CO <sub>2</sub> Electroreduction Activity on Pyridine Modified Gold Nanoparticles
ABSTRACT Ligand retention or modification at the surfaces of nanocatalysts can modulate catalytic performance, but the role of ligand coverage is often underappr...
Chiral Cages With Asymmetric π‐Clefts Enable Catalytic Enantioconvergent S <sub>N</sub> 1 Transformation via Synergistic Cation–π and Anion–π Interactions
ABSTRACT Understanding and exploiting noncovalent interactions are essential for advancing chemical transformations and catalysis. While both cation–π and anion–...
Dynamic Covalent Se─Se Bonds Enable Mechanically Adaptive Selenium Crystals
ABSTRACT Dynamic covalent chemistry has enabled adaptive behavior in organic polymer networks and molecular crystals, yet analogous control in inorganic crystalline solids remains la...
Managing Lattice Strain Enables Irreversible Single‐Crystal‐to‐Single‐Crystal Transformation of Covalent Organic Frameworks
ABSTRACT Covalent organic frameworks (COFs) typically rely on reversible covalent chemistry to achieve crystallinity, whereas irreversible and rigid linkages are generally required t...
Graphdiyne as a Hole‐Transport Channel in Carbon Nitride Heterojunctions for Synergistic CO <sub>2</sub> Reduction and <i>γ</i> ‐Butyrolactone Synthesis
ABSTRACT Coupling photocatalytic CO 2 reduction with organic oxidation promises enhanced solar energy conversion and atom...
Cage Catalyst: Tandem Assembly and Temperature‐Regulated Symmetry Breaking of Endogenous Metal Cluster for Phase‐Controlled CO <sub>2</sub> Electroreduction
ABSTRACT Encapsulation of metal clusters in porous organic cages (POCs) is a promising strategy for metalloenzyme‐mimetic catalysts. However, constructing POCs w...
Biocompatible Interface for Organic Electrochemical Transistors Enables Bioadhesion and Over‐Swelling Suppression
ABSTRACT Bioelectronic interfaces necessitate devices that not only align mechanically with biological tissues but also adhere effectively to wet surfaces and ma...
Energy‐Efficient Electrocatalytic Semi‐Hydrogenation of Alkynols by Synergistic Ni‐Fe Pairs and Ni Clusters on N‐Doped Carbon
ABSTRACT Electrocatalytic semi‐hydrogenation (ECSH) of alkynes using water as a hydrogen source is expected to provide a revolutionary solution for upgrading the...
Nearly 100% Valorization in Seconds: Transforming PET‐Metal Oxide Mixtures Into M <sub>1</sub> O <sub>x</sub> Clusters on rGO and Premium Syngas/Aromatics Products
ABSTRACT The efficient recycling of polyethylene terephthalate (PET) is often hindered by challenges such as low‐value products, limited processing capacity, pro...
Metal‐Complex‐Functionalized Terpolymer Donors Enabling Efficient Solar Cells via Enhanced Dielectric Constant and Minimized Triplet Exciton Loss
ABSTRACT The dielectric constant ( ε r ) critically influences exciton generation and subsequent diss...
Catalytic Enantioselective Multicomponent Reactions of Sulfoxonium Ylides Enabled by a Formal Rearrangement—A Versatile Entry to Enantioenriched α‐Sulfanyl Carbonyl Compounds
ABSTRACT Sulfur ylides have emerged as versatile carbenoids for catalytic enantioselective X–H insertion reactions (X = C, N, O, and S), while offering a better safety profile compar...