Angewandte Chemie International Edition
Articles in this Issue
Nickel‐Catalyzed Cross‐Electrophile Coupling of Alkynyl Halides With Allylic Acetates
ABSTRACT We have developed a Ni‐catalyzed cross‐electrophile coupling (XEC) strategy that enables the efficient synthesis of diverse skipped enynes from readily...
Two‐Dimensional Metal‐Organic Frameworks as Charge Extraction Media Enabling Binary Organic Solar Cells With 20.70% Efficiency
ABSTRACT Metal‐organic frameworks (MOFs), recognized for their tunable, highly conjugated frameworks and exceptional charge‐transport properties, exhibit signifi...
A Safe Approach to <i>meta</i> ‐Fluorinated Pyridines
ABSTRACT Since 1947, the Balz–Schiemann reaction has remained the most popular method for the synthesis of meta ‐fluoropy...
Synergistic Chirality Transmission and Energy Transfer in Clusteroluminescent Cholesteric Cellulose Derivatives for Amplified Circularly Polarized Luminescence
ABSTRACT Cellulose‐based systems provide unique advantages for constructing circularly polarized luminescence (CPL) materials owing to their intrinsic chirality and clusteroluminesce...
Fluorinated Cobalt Sites Enable Solar‐Enhanced Neutral Active Chlorine Electrosynthesis for In Situ Seawater Purification
ABSTRACT The electrocatalytic chlorine evolution reaction (ClER) provides a sustainable approach for converting abundant seawater chloride into highly reactive c...
Photocatalytic Synthesis of Aromatic Nitriles Using TiO <sub>2</sub> Nanotubes Decorated With Bismuth Halide Perovskite Nanodots
ABSTRACT The aromatic nitrile synthesis via ammoxidation of methylarenes typically requires harsh reaction conditions (≥ 350°C or ≥ 15 bar O...
Inside Back Cover: Nature‐Inspired Organic–Inorganic Hybridization Enables High‐Temperature and Multicolor Organic Phosphorescence (Angew. Chem. Int. Ed. 31/2026)
Enhancing Efficiency and Stability of Perovskite Solar Cells Through Electron‐Rich Covalent Organic Frameworks Radicals
ABSTRACT Effective regulation of perovskite crystallization is crucial for achieving high‐performance perovskite solar cells (PSCs). However, perovskite films ty...
Manganese Pyrophosphate Mineralized DNA Nanovaccine Elicits Potent Humoral and Cellular Immunity
ABSTRACT Subunit vaccines offer safety and precision but require adjuvants to overcome weak immunogenicity, particularly for the induction of cellular immunity. Herein, we develop a...
Ferritin Iron Mineralisation: Route of Fe <sup>3+</sup> Transfer From the Ferroxidase Centre to the Inner Cavity of Human H‐Chain Ferritin
ABSTRACT Ferritin‐catalysed Fe 2+ oxidation by reaction with O 2 occurs at an int...
Development of Sub‐50 nm Core–Shell Silica Nanoparticles With Controlled In Vivo Behavior for <sup>19</sup> F Magnetic Resonance Imaging
ABSTRACT 19 F magnetic resonance imaging ( 19 F MRI) enables quantitative and background‐free detecti...
Molecular Conformation‐Locking for Eye Care and Highly Efficient Narrowband Deep‐Blue Organic Electroluminescence
ABSTRACT The advancement of high‐color‐purity displays demands deep‐blue emitters that fulfil stringent colorimetric standards while minimizing photobiological r...
Dual‐Atom Dopants Activated Copper Dilute Alloy Boosts Electroreduction CO <sub>2</sub> ‐to‐C <sub>2+</sub> Products at Ampere‐Level Current Density
ABSTRACT Electrochemical CO 2 reduction reaction (CO 2 RR) with H...
Single‐Atom Iron‐Catalyzed Oxidative Esterification: From Methylarenes to the Upcycling of Polystyrene and Lignin‐Derived Feedstocks
ABSTRACT The catalytic oxidation of C─H bonds represents a transformative strategy for converting abundant hydrocarbons into high‐value functional molecules. We...
γ‐Ray Regulated Host–Guest Molecular Recognition
ABSTRACT Decades of advances in light‐responsive host–guest supramolecular systems allow precise molecular switching and photoactivation, yet their in vivo use i...
Solar‐Driven Carbon–Nitrogen Coupling Between Biomass‐Derived Alcohol and Ammonia for High‐Value Amine Synthesis
ABSTRACT Photocatalytic carbon–nitrogen (C–N) coupling of biomass‐derived alcohols and inorganic nitrogen sources provides a sustainable route to high‐value amin...
Gold(III) Semiquinone Complexes: Synthesis, Structure, and Application in Photocatalysis
ABSTRACT Recently, hemilabile ligands have been found to enable two‐electron Au(I)/Au(III) redox cycling. Yet, single‐electron processes and the use of redox‐active ligands in gold c...
Bifurcation of *COOH Pathway Determines HCOOH Formation in CO <sub>2</sub> Electroreduction on Bismuth
ABSTRACT Bismuth (Bi) is a promising electrocatalyst for the CO 2 reduction reaction (CO 2...
Mitochondria‐Targeted Photodynamic Agents Drive Robust Pyroptosis by Caspase‐3/GSDME Activation and Cardiolipin Externalization
ABSTRACT Photodynamic therapy (PDT)‐induced pyroptosis has attracted considerable interest as a strategy for cancer therapy, yet rational design of photosensitiz...
Asymmetric Reductive Three‐Component Annulation Reaction for Constructing Fused N‐Heterocycles With Contiguous Stereogenic Centers
ABSTRACT The development of efficient methods for the diverse synthesis of optically active fused N‐heterocycles is vital for advancing medicinal chemistry. Hydr...
Transient Polarized Cavities Mediate an Ultrafast and Stable Graphite Anode for Potassium‐Ion Batteries
ABSTRACT Conventional ester‐based electrolytes exhibit intrinsic limitations for potassium‐ion batteries (PIBs): ethylene carbonate is solid at room temperature,...
Reactivity of a d <sup>2</sup> Mo(IV) Alkylidyne Fragment Bearing a PNCNP Pincer Ligand Toward Alkynes: Coordination and Catalytic Alkyne Metathesis
ABSTRACT Currently, almost all alkyne metathesis catalysts are based on high valent d 0 Schrock‐type alkylidyne complexes...
Multivalent Antibody‐Recruiting Molecules for Targeted Immune‐Killing of Carbonic Anhydrase IX‐Expressing Cancer Cells
ABSTRACT Antibody clustering on the surface of cells enables recognition by Fc receptors on innate immune cells and activation of the complement cascade, resulting in elimination. Th...
Perylene Diimide‐Derived Bis(Macrocyclic) Ligand Affords Chiral Multinuclear Pd(II) Complexes via Direct Bay‐Region Palladation
ABSTRACT Macrocyclic ligands provide powerful access to structurally defined multi‐metallic architectures, yet direct π‐core metalation of imide‐functionalized p...
Semi‐Ionic C‐F Bonds Modulate Hydrogen Dynamics for Selective CO <sub>2</sub> ‐to‐CH <sub>4</sub> Electroreduction on Carbon Quantum Dots
ABSTRACT Electrochemical CO 2 reduction to CH 4 represents an attractive route fo...