Angewandte Chemie International Edition
Articles in this Issue
Late‐Stage Functionalization of Peptides on the Solid Phase
ABSTRACT Chemical modification is a means of tailoring the structure and function of peptides. This is of particular interest in the field of peptide drug development. Methods that e...
A Reversible 900 nm Near‐Infrared Photoswitch for Invisibly Writable 2D and 3D Displays
ABSTRACT Molecular photoswitches interchange between different states in response to light irradiation and represent prominent tools to deliberately control chan...
Inside Front Cover: Organic Intercalation Enables Controllable Single‐Atom Coordination for Efficient H <sub>2</sub> O <sub>2</sub> Electrosynthesis (Angew. Chem. Int. Ed. 31/2026)
Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
ABSTRACT Addressing small‐molecule chromophores with bioactive properties has been established as an effective means of controlling biological systems for several decades. However, t...
Engineering NIR Probes to Enhance Affinity and Clinical Workflow Compatibility for Prostate Cancer Imaging
Abstract Positive surgical margins following radical prostatectomy increase the risk of biochemical recurrence and subsequent disease progression. Fluorescence‐guided surgery (FGS) u...
Frontispiece: Artificial Transmembrane Channels for Selective Ascorbic Acid Transport and Bioorthogonal Signal Transduction
Correction to “Poly(2‐Oxazoline)‐Based Functional Peptide Mimics: Eradicating MRSA Infections and Persisters While Alleviating Antimicrobial Resistance”
Prasenjit Mondal
Artificial Transmembrane Channels for Selective Ascorbic Acid Transport and Bioorthogonal Signal Transduction
ABSTRACT Ascorbic acid (AA), an essential bioactive molecule, plays a pivotal part in maintaining physiological functions in cells and organisms, and its intracellular homeostasis is...
Quasi‐Closed‐Loop Crystal–Amorphous Solid–Wet Gel Transformation in Copper MOFs for Exceptional Cycling Stability in Cascade Reactions
Abstract Quasi‐closed‐loop transformations between crystals, amorphous solids, and wet gels are rarely explored in metal–organic frameworks (MOFs). We report a stimuli‐responsive Cu(...
Enantioselective Vinyl Radical Addition to Aldehydes via Dual Chromium Catalysis
ABSTRACT Achieving stereocontrol in radical‐mediated transformations remains a fundamental challenge, with the enantioselective manipulation of highly reactive vinyl radicals being p...
In Situ Amplified Mutational mRNA Imaging Using a Spatially Confined CRISPR Nanoplatform
ABSTRACT Highly sensitive spatial analysis of RNA mutations is essential for understanding cellular heterogeneity and disease mechanisms. Herein, we developed an...
Ordered Ionic‐Liquid Channels Enable Fast Anhydrous Proton Conduction at up to 240°C for Fuel Cells
ABSTRACT Intermediate‐temperature electrochemical technologies offer a range of important advantages but require high‐performance and robust anhydrous proton exc...
Modeling CO <sub>2</sub> Hydrogenation to Methanol on an Ensemble of Inverse ZrO <sub>2</sub> on Cu Catalytic Sites: Mechanism, Reactivity, and Deactivation
ABSTRACT Inverse ZrO 2 /Cu catalysts, where Zr oxide is deposited on Cu particles, show a high catalytic performance conv...