Angewandte Chemie International Edition
Articles in this Issue
Interfacial Water Structure Modulation on Unconventional Phase Non‐Precious Metal Alloy Nanostructures for Efficient Nitrate Electroreduction to Ammonia in Neutral Media
Abstract Electrocatalytic nitrate reduction reaction (NO 3 RR) has been recognized as a sustainable route for nitrate rem...
High‐Security and High‐Efficiency Information Encryption/Decryption Based on 2D Hybrid Organic–Inorganic Perovskites via Delicate Organic‐Cation Engineering
Abstract Optical encryption based on stimuli‐responsive luminescence (SRL) materials has received enormous interest in the field of information security. Metal–h...
Regulated Second‐sphere Coordination in Amorphous Metal‐organic Framework for Efficient CO <sub>2</sub> Fixation
Abstract The endeavor toward photocatalytic CO 2 fixation is largely hampered by the rigid spatial configurations and ina...
Evoking Simultaneous Ferroptosis and Apoptosis by a Dual‐Locked Platinum (IV) Prodrug for Synergistic Chemo‐immunotherapy
Abstract While platinum‐based chemotherapeutics have revolutionized cancer treatment, their clinical potential is limited by off‐target toxicity and restricted antitumor mechanisms....
Cytochrome P450 Mediated Cyclohexane Ring Formation in Forazoline Biosynthesis
Abstract Forazoline A, produced by the marine actinomycete Actinomadura sp. WMMB‐499, is a unique PK/NRP hybrid macrolact...
Chloromethylation Modified Pyranonitrile‐Based Conjugated Microporous Polymers for Selective One‐Step Two‐Electron O <sub>2</sub> Reduction to H <sub>2</sub> O <sub>2</sub>
Abstract Hydrogen peroxide (H 2 O 2 ) production utilizing conjugated microporous...
Induced Chirality and Vibrational Optical Activity in an Ionic‐Liquid Anion
Abstract Here, we show that the four conformers of the regularly used ionic liquid anion bis(trifluoromethylsulfonyl)imide are true enantiomeric pairs by analyzing their calculated...
Ternary Aldehyde–Copper–Iridium Catalysis Enables Stereodivergent Allylation via α‐C‐H Functionalization of Primary Amines
Abstract α‐Chiral primary amines are recognized as one of the most valuable and versatile synthetic intermediates, widely utilized in the construction of diverse...
Defect‐Triggered Orbital Hybridization in FeMn Dual‐Atom Catalysts Toward Sabatier‐Optimized Oxygen Reduction
Abstract Dual single‐atom catalysts (DSAs), leveraging synergistic dual‐site interactions, represent a promising frontier in electrocatalysis. However, the preci...
Tri‐Coordinated Boron Species in Confined Boron Oxide Catalysts for Enhanced Low‐Temperature Oxidative Dehydrogenation of Propane
Abstract Boron‐based catalysts exhibit great potential for oxidative dehydrogenation of propane (ODHP) to produce olefins. The straightforward synthesis of confi...
Enantioselective Palladium‐Catalyzed α‐Arylation of Acyclic Esters
Abstract A Pd‐catalyzed enantioselective α‐arylation of α,α‐disubstituted esters with aryl bromides is established for the first time by employing P‐chiral monop...
Dopant and Exfoliation Induced Simultaneous Modification of Charge Density and C─C Coupling Sites for Efficient CO <sub>2</sub> Photoreduction to Ethylene
Abstract The photochemical conversion of CO 2 into C2+ products has emerged as an attractive method for synthesizing valu...
Tumor‐Specific On‐Site Activation of Cisplatin via Cascade Catalytic‐Redox Reactions for Highly Efficient Chemo‐Immunotherapy
Abstract The therapeutic efficiency of platinum drugs is always limited by low utilization, side effects, and Pt‐resistance. Herein, a double‐lock protected Pt...
Turing‐Structured Covalent Organic Framework Membranes for Fast and Precise Peptide Separations
Abstract Turing structures have emerged as promising features for separation membranes, enabling significantly enhanced water permeation due to their ultra‐perme...
Activating Surface Oxygen in Ce/Mo‐Doped Ni Oxyhydroxide for Synergistically Enhancing Furfural Oxidation and Hydrogen Evolution at Ampere‐Level Current Densities
Abstract The integration of biomass‐platform molecule oxidation with water electrolysis is a promising strategy to reduce energy consumption in hydrogen producti...
Outside Back Cover: Polyphosphorus Ligand Complexes of Coinage Metals for Multiple Capturing of Intact P4 Tetrahedra (Angew. Chem. Int. Ed. 28/2025)
Construction of Shamrock‐Shaped Giant Molecule Acceptors for Efficient Organic Solar Cells
Abstract The discovery of non‐fullerene small molecule acceptor materials has breathed new development into organic solar cells (OSCs). However, it has also intr...
Boosting Urea Electrosynthesis via Asymmetric Oxygen Vacancies in Zn‐Doped Fe <sub>2</sub> O <sub>3</sub> Catalysts
Abstract Urea electrosynthesis from CO 2 and nitrate (NO 3 −...
Manipulation of Hydrogen Transfer Behaviors by RhCu Alloying Enables an All‐in‐one Sustainable “Furfural‐Nitrate” System
Abstract Nitrate and furfural are typical wastes mainly from industrialization and agriculturalization progresses, and their clean conversions are still very cha...
Iron‐Catalyzed Radical Allylic Substitution of Unprotected Allylic Alcohols
Abstract Allylic substitution reactions are essential in organic synthesis, enabling the transformation of allylic reagents into diverse alkenes. Traditional met...
Peter A. Korevaar
The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of <i>Plasmodium</i> Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria
Abstract New compounds targeting human malaria parasites are critical for effective malaria control and elimination. Here, we pursued the imidazoquinolinone AZD0...
Unlocking One‐Step Two‐Electron Oxygen Reduction via Metalloid Boron‐Modified Zn <sub>3</sub> In <sub>2</sub> S <sub>6</sub> for Efficient H <sub>2</sub> O <sub>2</sub> Photosynthesis
Abstract The indirect two‐step two‐electron oxygen reduction reaction (2e − ORR) dominates photocatalytic H...
Dihydrophenazine Derived Pd <sub>6</sub> L <sub>12</sub> Cage: Self‐Assembly, Polyradical Cations, and Lithium Battery Cathode Application
Abstract In this study, we present the self‐assembly of a dihydrophenazine‐based Pd 6 L 12...
Site‐Specific Spin State Modulation in Spinel Oxides for Enhanced Nonradical Oxidation
Abstract Spinel oxides hold tremendous potential for driving advanced oxidation processes, yet the underlying mechanism for maximizing their activity remains unc...