Angewandte Chemie International Edition
Articles in this Issue
Improving Mass Transport and Charge Transfer in COF‐Based Photocatalysts With Three‐Dimensional Ordered Macropores for Benzylamine Oxidation and Hydrogen Evolution
Abstract Covalent organic frameworks (COFs) have shown promise as photocatalysts for chemical transformations. However, their dense micropores and poor pore conn...
Inside Front Cover: AM‐DMF‐ddRPA: an All‐in‐One Digital Microfluidic Platform for Rapid and Automatic Digital Nucleic Acid Analysis (Angew. Chem. Int. Ed. 34/2025)
Wide‐Temperature, High‐Voltage, Flame‐Retardant Electrolyte for 4.8 V Li||NCM94 Batteries
Abstract All‐climate lithium metal batteries attract great interest, but their poor safety and cycling performance hinder their applications, especially with hig...
Rational Design Strategies in DNA‐Encoded Libraries for Drug Discovery
Abstract DNA‐encoded libraries (DELs) have emerged as a powerful and cost‐effective platform for high‐throughput screening, enabling the rapid identification of small‐molecule ligand...
A Dual‐Atom La <sub>2</sub> Catalyst for the Oxygen Reduction Reaction
Abstract Rare earth lanthanum element has a large atomic radius, multi‐shell orbital electrons, and Fenton‐like reaction inertia, on which a localized high‐coord...
Switching Photocatalytic Methane Oxidation Toward Ethanol by Tuning Spin States
Abstract The selective oxidation of methane (CH 4 ) has attractive potentials for mitigating global warming and producing...
Efficient Electro‐Oxidation of Ethylene to 2‐Chloroethanol on SnO <sub>2</sub> Through Dual‐Adsorbate Pathway
Abstract Electrified 2‐chloroethanol synthesis serves as a promising alternative to conventional ethylene oxidation with corrosive hypochlorous acid (HClO) and o...
Embracing Complexity: Peptides as Tunable Scaffolds in the Construction of Discrete Supramolecular Systems
Abstract Supramolecular chemistry has advanced rapidly, with scientists using fundamental understanding to generate function from simple building blocks. However, synthetic systems a...
Anisotropy of Single‐Crystal Semiconductors in Photo(electro)Catalysis
Abstract Anisotropy in single‐crystal semiconductors has emerged as a key design principle for understanding and advancing photo(electro)catalytic systems. The exposure of well‐defin...
Engineering Graphene Nanoribbons via Periodically Embedding Oxygen Atoms
Abstract Heteroatom doping is an important method for engineering graphene nanoribbons (GNRs) because of its ability to modify electronic properties by introduci...
Tunable <i>Endo</i> / <i>Exo</i> Selectivity in Direct Catalytic Asymmetric 1,3‐Dipolar Cycloadditions with Polyfunctional Lewis Acid / Azolium–Aryloxide Catalysts
Abstract Catalytic asymmetric 1,3‐dipolar cycloadditions (1,3‐DCA) using iminoesters as ylide precursors offer a powerful approach to accessing stereochemically...
Branched‐Selective Functionalization of 2‐Alkyl Aziridines Through Ni‐Catalyzed Dynamic Kinetic Activation
Abstract Overriding the inherent substrate‐controlled regioselectivity in aziridine activation holds significant potential. It could enable previously inaccessible disconnections fro...
Orchestrating Penta‐Element Interplay in Gradient‐Porous Carbons for Advanced Sodium‐Ion Hybrid Capacitors
Abstract Sodium‐ion hybrid capacitors (SIHCs) offer a cutting‐edge synergy between battery‐level energy density and supercapacitor‐like power density, yet face c...
Quantitative Tracking of Apoptotic Caspase‐3 In Vivo for Early Evaluation of Radiation Therapy Efficacy
Abstract Traditional responsive fluorescent probes are predominantly restricted to qualitative biomarker detection, incapable of delivering real‐time quantitativ...
Overcoming Challenges in Small‐Ring Transfer: Direct Decarboxylative Hydroalkylation of Alkenes via Iron‐Thiol Catalysis
Abstract Cyclopropanes, especially those substituted with trifluoromethyl (CF 3 ) groups, are valuable scaffolds in medic...
Spring‐Like Behavior in [8]Helicene Diimides: How Helical Pitch Governs Optical Anisotropy and Electronic Conjugation
Abstract Helicenes, with their corkscrew‐shaped geometry, have emerged as prototypical molecular springs for engineering chiral functional materials through prec...
Electron‐Delocalized Cu <sup>2+</sup> Activates Spin Channels in Spinel Oxides to Selectively Produce <sup>1</sup> O <sub>2</sub> for Wastewater Treatment
Abstract Blocked electron transfer in the catalyst during advanced oxidation processes causes sluggish singlet oxygen ( 1...
A Butterfly‐Like Fluorescent Tracker for Dynamic Polymers
Abstract Optically tracking constitutional dynamics provides a time‐resolved, non‐invasive, and visually interpretable approach to unraveling microscopic complexity in system chemist...
Correction to “Cell‐Active, Arginine‐Targeting Irreversible Covalent Inhibitors for Nonkinases and Kinases”
Integrated Chemoenzymatic Synthesis of the mRNA Vaccine Building Block <i>N</i> <sup>1</sup> ‐Methylpseudouridine Triphosphate
Abstract Pseudouridine‐5′‐triphosphate (ΨTP) and its N 1 ‐methylated derivative (m...
Regioselective C─H Functionalization by the Combination of Enzymatic and Chemocatalytic Reactions in Water
Abstract The combination of bio‐ and chemo‐catalytic processes has tremendous potential for the sustainable production of important synthetic building blocks. Su...
Inside Back Cover: A Butterfly‐Like Fluorescent Tracker for Dynamic Polymers (Angew. Chem. Int. Ed. 34/2025)
Stepwise Acetylene Insertion and Ammonia Activation at a Digallene and Diindene
Abstract Sequential [2 + 2] cycloaddition reactions between acetylene and the digallene and diindene compounds (ETer) 2 (...
Origin of Anion‐Rich Solvation Structures in Siloxane Electrolytes
Abstract High‐voltage lithium (Li) metal batteries (LMBs) are promising next‐generation high‐energy‐density rechargeable batteries. Siloxane electrolytes exhibit...