Angewandte Chemie International Edition
Articles in this Issue
Inside Back Cover: BN/BO Doping of <i>Peri</i> ‐Acenoacenes: Modulating Excited States in Trapeziumene Congeners (Angew. Chem. Int. Ed. 44/2025)
Tailoring the Magnetic Properties of 2D Metal‐Organic Networks by Harnessing the Coordination Sphere
Abstract Achieving magnetic ordering in low‐dimensional materials remains a key objective in the field of magnetism. Herein, coordination chemistry emerges as a powerful discipline t...
Ni‐Mediated High‐Spin Iron(III) for Boosting Electrocatalytic NO to Oxime Conversion
Abstract Oximes serve as indispensable intermediates in synthetic chemistry, owing to their distinctive C═N─OH structure, conferring highly versatile reactivity. Synthesis of oxime v...
Amyloid Peptide Nanofibrils Promote Efficient Neurotransmitter Oxidation and Serve as Scaffolds for Melanin Production
Abstract We have shown that de novo designed peptides self‐assemble in the presence of copper to create supramolecular assemblies capable of carrying out the oxidation of a range of...
Single‐Molecule Dual‐Anchor Design Enables Extreme‐Condition Lithium Metal Batteries Through Solvation Reconstruction and Cathode Polymerization
Abstract Lithium metal batteries (LMBs) have emerged as the most promising candidate for next‐generation high‐energy‐density energy storage systems. However, the...
Inverting the Rhodamine Paradigm: Closed‐Form Fluorescence with 280 nm Stokes Shift Drives Plastic Circularity
Abstract Rhodamine derivatives exhibiting inverted open‐closed form fluorescence behavior redefines conventional photochemical paradigms while illuminating new s...
One‐Pot Sequential Coordination–Covalent Construction of Symmetry‐Broken MN <sub>2</sub> O <sub>2</sub> Catalytic Sites in Cobalt–Polyimide Polymers for Nitrate Electroreduction
Abstract The metal‐nitrogen chelated species, MN 4 , have shown promise as efficient electrocatalysts for nitrate reducti...
On‐Target Photoassembly of Pyronin Dyes for Super‐Resolution Microscopy
Abstract Controlled photoactivation is an auspicious and emerging approach in super‐resolution microscopy, offering virtually zero background signal from the marker prior to activati...
Wavelength Selective Single Molecule Photobase/Photoacid Generator Enabling Dynamic Control of Soft Matter Materials Functions
Abstract Photoremovable protecting groups (PRPGs) enable precise spatiotemporal control over molecular release and functional activation. Recent advances have in...
Hetero‐Hydrazone Photoswitches
Abstract The fine‐tuning of the (photo)physical properties of molecular photoswitches remains an active area of research, and recently, the incorporation of heterocycles into photosw...
Hydrogen Radical Mediated Concerted Electron−Proton Transfer in 1D Sulfone‐based Covalent Organic Framework for Boosting Photosynthesis of H <sub>2</sub> O <sub>2</sub>
Abstract Solar‐driven photocatalytic oxygen reduction reaction using covalent organic frameworks (COFs) offers a promising approach for sustainable hydrogen pero...
Ligand‐Enabled Cu‐Catalyzed Deoxyalkynylation of α‐Unfunctionalized Alcohols with Terminal Alkynes
Abstract Despite the widespread utility of transition metal‐catalyzed cross‐couplings in organic synthesis, the coupling of unactivated alkyl electrophiles remai...
MitoSiege‐Driven Catalase Collapse: A GSH‐Responsive, Mitochondria‐Targeted COF Prodrug for Amplified Chemodynamic Therapy
Abstract Chemodynamic therapy (CDT), leveraging Fenton reactions to generate hydroxyl radicals (•OH) from intracellular hydrogen peroxide (H...
Synthesis and Application of Bioactive <i>N</i> ‐Functionalized Aziridines
Abstract Aziridines—three‐membered nitrogen heterocycles that engage in strain‐accelerated ring opening chemistry—are not common functional groups in bioactive natural products. As s...
Himchan Cho
Asymmetric Electronic Distribution at Mn–Cu Dual Atomic Sites Promoting Electrochemical Conversion of N <sub>2</sub> to NH <sub>3</sub>
Abstract Electrochemical synthesis of ammonia (NH 3 ) is a promising green alternative to the conventional Haber‐Bosch pr...
Changing Self‐Assembly Through Degradation: Phenyl Vinyl Ketone Polymer Nanoparticles Under Light
Abstract Photodegradable nanoparticles with sphere, worm, and vesicle morphologies were synthesized following polymerization induced self‐assembly (PISA), incorp...
Self‐Assembled Polypseudorotaxanes Crosslinked by Dynamic Disulfide Bonds as Modular Functionalization for Thiophilic Metal Nanoparticles
Abstract As supramolecular assemblies, polypseudorotaxanes (PPR) exhibit inherent advantages in modular adaptability and structural programmability, with the potential to build tunea...
Atomic‐Scale Mechanistic Insights into the Ring‐Opening Polymerization of Elemental Sulfur
Abstract A detailed understanding of the composition and polymerization mechanism of elemental sulfur remains a decades long unresolved question for modern chemistry. However, the dy...
Dual‐Locked Polymeric STING Nano‐Agonist/Sonosensitizer Augments Spatiotemporally Controlled Cancer Sono‐Immunotherapy
Abstract The stimulator of interferon genes (STING) pathway is a central target in cancer immunotherapy, but current STING agonist therapies lack precision control, leading to subopt...
Oxygen‐Tolerant, Red Light‐Driven Controlled Synthesis of Easily Degradable and High Molecular Weight <i>α</i> ‐Lipoic Acid‐Vinyl Copolymers
Abstract α‐Lipoic acid (LA) has recently emerged as an attractive, inexpensive monomer for synthesizing degradable polymers via ring‐opening of its 1,2‐dithiolan...
Inside Front Cover: Tunable Copolymerization of Oxetane and Anhydrides via a Nonsymmetric Three‐Center Four‐Electron Iodine Activation Mode (Angew. Chem. Int. Ed. 44/2025)
Lithium‐Mediated Hydrochloric Acid Dissolution: Enabling Clean and Efficient Recovery of Palladium from Spent Catalysts by Electrodeposition
Abstract To address palladium supply–demand challenges and conventional recovery inefficiencies, this study develops a lithium‐mediated electrodeposition process...
Emphasizing <i>a</i> ‐parameter Expansion in Lattice Distortions of Disordered Rock Salt Li <sub>3</sub> V <sub>2</sub> O <sub>5</sub> : From Crystallographic Design to Feasible Large‐Scale Chemical Lithiation
Abstract Disordered rock‐salt Li 3 V 2 O 5...
Anchoring Ligand Electron Enables Robust Metal‐Oxygen Coordination Toward 4.5 V O3‐Type Sodium‐Ion Battery Cathodes
Abstract High‐voltage operation enables sodium‐sufficient O3‐type layered oxides to approach the maximum achievable energy densities for practical sodium‐ion bat...