Angewandte Chemie International Edition
Articles in this Issue
Iridium‐Catalyzed Enantioselective Formal <i>meta</i> ‐Allenylation of Pyridines
Abstract Site‐selective functionalization of pyridines is an important yet challenging transformation. Temporary dearomatization of pyridines through redox‐neutr...
Spillover Hydrogen Boosts Nitroarene Hydrogenation to Industrial Activity with Ppm‐Level Platinum Single Atoms
Abstract The application of noble single‐atom catalysts (SACs) at trace loadings is constrained by a low space‐time yield, presenting a formidable challenge in e...
Correction to “Gas‐Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy”
Fe−O−Mo Site‐Activated Nanozymes for Bienzymatic/Upconversion Synergistic Catalytic Anticancer Therapy
Abstract Single‐atom nanozymes (SAzymes) hold promise for cancer therapy but suffer from low active site density and restricted intermediate adsorption/desorptio...
Total Synthesis of Calyciphylline F
Abstract Calyciphylline F represents the final challenge in the total synthesis of the caged polycyclic‐type of Daphniphyllum...
Hot Electron Photocatalysis Using Nontoxic Self‐Doped Quantum Dots
Abstract Colloidal semiconductor quantum dots (QDs) have emerged as versatile photocatalysts for organic transformations. However, a significant drawback is thei...
3D Gas Diffusion Layer with Dual‐Metal Sites for Enhanced CO <sub>2</sub> Electrolysis to C <sub>2+</sub> Products
Abstract Achieving satisfactory C 2+ products selectivity and current density in the electrochemical CO...
Evolution of Circularly Polarized Luminescence in Atomically Precise Silver Nanoclusters with Intrinsic Chirality
Abstract Circularly polarized luminescence (CPL) is a powerful tool to probe the chiroptical properties of molecular systems in the excited state. Here, we demon...
One‐Step Silver Leaching from Manganese–Silver Ore Enabled by Hydrogen‐Bonded Network Formation
Abstract Silver is an increasingly scarce resource, necessitating green leaching methods for low‐grade ores. Conventional cyanidation, however, suffers from extr...
A Heterodimetallic Monomeric Complex with a Uranium–Cobalt Triple Bond
Abstract The crystal structure of heterodimetallic monomeric complexes featuring a U–M triple bond has been rarely reported. Here, we present an example of a het...
Cupin‐Type Dimethylsulfoniopropionate Lyase from <i>Pelagibacter ubique</i> (DddK <i> <sub>Pu</sub> </i> ) Catalyzes Aza‐Michael Addition of Primary and Secondary Amines to Acrylic Acid
Abstract The formation of carbon─nitrogen (C─N) bonds is a cornerstone of organic synthesis, underpinning the production of amines, imines, and nitriles found in...
Stereodivergent Assembling Tsuji–Trost Reaction via Photoinduced Pd and Pd/Ir Relay Catalysis
Abstract Tsuji–Trost reaction typically relies on the use of alkenes containing an α‐leaving group as the substrates. In comparison, an in situ assembling model...
A Self‐Homing Liposomal Nanobot for Active Therapy of Glioblastoma
Abstract Glioblastoma (GBM) remains a substantial obstacle in therapy since the blood–brain barrier (BBB) and tumor microenvironment (TME) severely prevent the access of most exogeno...
Inside Back Cover: Two‐Dimensional Heterovalent Alloying Hybrid Double Perovskite Solid Solution for Elevating Ferroelastic Photoelectric Response (Angew. Chem. Int. Ed. 45/2025)
Atomic Structure Design for Enhancing Metal‐Support Frontier Orbital Interaction to Achieve Efficient Photocatalytic H <sub>2</sub> O <sub>2</sub> Generation
Abstract Modified g‐C 3 N 4 has been widely applied in various photocatalytic rea...
A Photothermal Nano‐Switch for Tumor‐Selective Wnt Hyperactivation in Vivo
Abstract Wnt signaling plays a paradoxical role in cancer, functioning as both a promoter and suppressor depending on its activation level. This duality underscores the critical need...
K <sup>+</sup> Vacancies and Fluorine Substitution Synergistically Regulate KTiOPO <sub>4</sub> Anode for All‐Climate and Long‐Life Potassium‐Ion Batteries
Abstract Although Ti‐based polyanion anode materials with robust structures exhibit advantages such as high reversibility and high Coulombic efficiency for alkal...
Regioselective Zr <sub>5</sub> Nanocluster Photocatalyst for Precise Protein Editing Under Mild Conditions
Abstract Understanding the impact of oxidative modifications on protein structure and function is of central importance in protein chemistry, necessitating preci...
Frontispiece: Radical Ring‐Opening Reaction of Non‐Activated Oximes Catalyzed by Aldoxime Dehydratases
Unlocking High‐Performance Four‐Electron Zinc‐Iodine Batteries through Halogen Bonding Inversion and Non‐Identical‐Frequency Molecular Vibrations
Abstract The activation of four‐electron transfer behavior through I − /I 0 /I...
Electronic Structure‐Engineered Proton Depletion Interfaces on Ternary RuO <sub>2</sub> for Ultra‐Stable Kilowatt Electrocatalysis
Abstract Advancing high‐current PEM water electrolysis (PEMWE) is crucial for terawatt‐scale green hydrogen economies, but anode catalyst stability under industr...
Acid‐Responsive Two‐photon Absorption Switch via Cocrystal‐to‐Salt‐to‐Cocrystal Conversion
Abstract Stimuli‐responsive organic cocrystals are typically governed by single‐crystal to single‐crystal (SCSC) transformation, remaining a long‐standing challe...
Frontispiece: Circumventing Radical Generation on Fe–V Atomic Pair Catalyst for Robust Oxygen Reduction and Zinc–Air Batteries
Reduction of Rare‐Earth Stannole Sandwich Complexes to Tin‐Based Radical Ligands and Tin–Tin Bonds
Abstract f‐Element organometallic chemistry is dominated by cyclopentadienyl ligands. In contrast, isoelectronic metallole ligands with the general formula [EC...
Formal C─H Functionalization of Quinolines at the C7 Position Through a Traceless Directing Strategy
Abstract The precise C─H functionalization of quinolines is of high interest in organic synthesis and drug discovery. However, although many strategies have been...