Angewandte Chemie International Edition
Articles in this Issue
On the Viability of Carbonyl Hydroboration Catalysed by Aluminium Hydrides
Abstract The hydroboration of aldehydes and ketones by pinacolborane (HBpin) catalysed by (Nacnac) Dipp Al(OTf)H ((Nacnac...
Atroposelective Synthesis of Enamine‐Based Axially Chiral Styrenes via CuH‐Catalyzed Hydroamination of Internal Alkynes
Abstract Despite the significant potential of axially chiral enamines, their efficient synthesis remains a challenge. Herein, we report a new approach for the di...
Enhanced Emission in Core@Shell Heterostructure of 3D Halide Double Perovskites
Abstract Inorganic metal halide double perovskites (HDPs) have successfully addressed the toxicity and instability concerns of lead‐based perovskites. However, t...
Single‐Cell Antimicrobial Susceptibility Testing via Stimulus‐Responsive Resonance Raman Scattering Imaging
Abstract Antimicrobial resistance (AMR) has emerged as a formidable worldwide public health crisis. Antimicrobial susceptibility testing (AST), the current gold...
Structural Transformation and Photochromism of Chiral Hybrid Metal Halides for Stimulus‐Responsive Phosphorescence and Circularly Polarized Luminescence
Abstract Chiral organic–inorganic hybrid metal halides (OIMHs) have emerged as promising systems for stimuli‐responsive circularly polarized luminescence (CPL)....
Imidazolium‐Derived Porous Organic Polymer as Robust Platform for Rhodium‐Catalyzed N <sub>2</sub> O Hydrogenation and Alcohol Oxygenation
Abstract The catalytic conversion of nitrous oxide, a potent greenhouse gas and ozone‐depleting substance, offers a promising strategy for mitigating emissions but requires efficient...
Constructing Sari‐Topology Covalent Organic Frameworks from Pseudo‐C <sub>5</sub> ‐Symmetric Core for Enhanced Oxygen Reduction Reaction
Abstract Developing new topologies for two‐dimensional covalent organic frameworks (2D COFs) remains challenging due to the scarcity of geometrically comparable...
Concurrent Ferroptosis and Pyroptosis Induced by a Dual‐Organelle‐Targeted Type I/II AIE Photosensitizer for Bladder Cancer Immunotherapy
Abstract The therapeutic efficacy and cell death modalities of photodynamic therapy (PDT) highly depend on reactive oxygen species (ROS) generation mediated by photosensitizers (PSs)...
Nanocellular Organelle Engineering for Optimizing Reaction Microenvironments in Nitrate‐to‐Ammonia Electrocatalysis
Abstract Certain natural catalysts, biological enzymes, tend to be confined within cellular organelles to achieve high catalytic efficiency in small molecule con...
Wide‐Temperature Operation of High‐Capacity Aqueous Chlorine Batteries Enabled by Complexation Chemistry
Abstract Rechargeable aqueous batteries based on the chloride/chlorine (Cl − /Cl 2...
Transition‐Metal‐Free Carbonyl Redox: A Ketene in Three Oxidation States
Abstract Ketenes are among the most versatile compounds in organic chemistry, participating in a wide range of transformations, including cycloadditions, nucleophilic and electrophil...
Difluoro Carbenes: From Genuine Gold Complexes to Unprecedented Metallacyclic Reactivity
Abstract Difluorocarbene is a very powerful synthon in organic chemistry, but its reactivity is very challenging to tame. While a few recent studies have pinpointed the potential of...
Triangular Nanotoroids Self‐Assembled from Polypeptide Homopolymers: The Formation Route and Mechanisms
Abstract Polymer nanotoroids have attracted increasing attentions recently. The topology of the nanotoroids is mainly limited to circular form, while noncircular forms are rarely obs...
Covalent Organic Frameworks Anchoring Single‐Atom Pt for Three‐Phase Interface‐Assisted Photocatalytic Overall Water Splitting
Abstract Covalent organic frameworks (COFs) are promising photocatalysts for overall water splitting (OWS) due to their high crystallinity, porosity and tunable...
Ion‐Dipole Interaction Induced Rigid‐Flexible Coupling SEI for Ultrastable Sodium Storage of Microsized Sn Anode
Abstract Tin (Sn) anode has been considered as a promising candidate for sodium‐ion batteries due to its high theoretical capacity and suitable operating potenti...
Broadly Tunable Liquid‐State Lasers and Solid‐State Single‐Longitudinal‐Mode Near‐Infrared Lasers Utilizing Halogen‐Doped Graphene Quantum Dots
Abstract Understanding the lasing mechanism of graphene quantum dots (GQDs) is crucial for enhancing their gain characteristics and developing high‐performance l...
Formation of Monolithic Magnesium–Calcium Carbonates Through Aggregation of Carbonate‐Cluster Nanodroplets
Abstract Mineral nucleation is a fundamental process of paramount importance to various fields, including geology, biomineralization, and industrial manufacturin...
The First Ferrocene‐Based Molecular Ferroelectric Accompanied by Spatial Symmetry Operation Breaking
Abstract Ferroelectric materials with switchable spontaneous polarization have attracted significant interest over the past decades. Molecular ferroelectrics par...
Enhancing Ionic Transport at Primary Interparticle Boundaries of Polycrystalline Lithium‐Rich Oxide in All‐Solid‐State Batteries
Abstract Polycrystalline lithium‐rich oxide (PLRO) is a promising high‐capacity cathode for next‐generation all‐solid‐state batteries (ASSBs). However, its full...
Rapaprotin, an Endopeptidase‐Activated Proteasome Inhibitor that Induces 26S Disassembly
Abstract The 19S regulatory particle (RP) associates with the 20S core particle (CP) to form the 26S proteasome, an evolutionarily conserved holoenzyme that plays key roles in both p...
Dual Regulation of Reduction and Oxidation Center in Metal–Organic Frameworks to Boost CO <sub>2</sub> Photoreduction
Abstract The efficiency of photocatalytic CO 2 reduction is governed by multiple critical factors, including visible‐ligh...
Rapid Construction of a Tyr C6–Trp C5′ Linkage: Application in the Total Synthesis of Micitide 982, a Noncanonical Cyclic Peptide
Abstract In this study, a facile synthesis method for a highly strained Tyr C6‐to‐Trp C5′ linkage was developed. This method enables the convergent introduction of arbitrary biaryls...
Topologically Tunable α‐Helix Mimetics for Targeting Protein–Protein Interactions
Abstract A novel strategy to replicate diverse α‐helical conformations found at the interfaces of protein–protein interactions is developed with a topologically tunable biphenyl scaf...
Thiazole‐2‐Carbaldehyde‐Based Covalent Organic Frameworks
Abstract We first synthesize a novel aldehyde‐substituted benzo[1,2‐d:4,5‐d']bis(thiazole) monomer (BBTC) via a facile method with a high yield, and the BBTC is...