Angewandte Chemie International Edition
Articles in this Issue
Hydroxylamine Cation as B‐Site with Radius and Dipole Moment Modulation for Metal‐Free Halide Perovskite to Enhance X‐ray Detection Performance
Abstract Nowadays, metal‐free halide perovskites (MFHPs) with good structural tunability, biocompatibility, and light weight have been studied in the X‐ray field...
Frontispiece: A General Strategy to Develop Intramolecular Spirocyclic Boron Dipyrromethene Fluorophores for Self‐Blinking Super‐Resolution Imaging
“Noninnate” Ring‐Opening Polymerization: Palladium‐Catalyzed Stereoselective 1,4‐Polymerization of Alkynylcyclopropanes
Abstract In ring‐opening polymerization (ROP), main‐chain connectivity is largely dictated by the inherent electronic and steric properties of the monomer. As a result, even when dif...
Dynamic Kinetic Resolution Polymerization: Synthesis of Chiral Polythioesters from Racemic Monomers
Abstract Chiral polymers are fundamentally important and interesting in nature and scientific research. For the preparation of chiral polymers, the standard kine...
Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs
Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as pro...
Enantioselective Synthesis of Mechanically Planar Chiral Rotaxanes by an Asymmetric Povarov Reaction‐Enabled Desymmetrization
Abstract Mechanically planar chiral (MPC) rotaxanes are a type of chiral mechanically interlocked molecules (MIMs) characterized by their unique chiral structures and dynamic motion...
Ionic Covalent Organic Framework Membranes for Rapid Moisture‐Driven Actuation and Sensing
Abstract The development of smart materials capable of rapid and reversible responses to ambient humidity is essential for next‐generation sensors, monitoring sy...
A Theory‐Driven Moderation Strategy for Electrolyte Design Unlocks Stable Aqueous Zinc Deposition
Abstract How theoretically screened solvation characteristics of additives affect zinc deposition behavior has emerged as a critical question of both scientific...
Harnessing Halogen Bonds in Porous Molecular Crystals for Efficient SF <sub>6</sub> /N <sub>2</sub> Separation
Abstract Halogen bonding offers a directional and tunable noncovalent interaction that remains underexplored in the design of porous molecular materials. Here, w...
Smart Adaptive Artificial Channels Triggered by Hypoxia for Highly Selective Apoptosis in Cancer Cells
Abstract In nature, hypoxia‐sensitive ion channels regulate the ion transport in response to oxygen levels, which are critical for cellular adaptation to low‐oxy...
Ni‐Bridged Biphasic Molybdenum Carbide Interfaces: A Synergistic Catalyst for High‐Performance Lithium–Selenium Batteries
Abstract Transition metal catalysts are key to developing high‐performance lithium‐selenium (Li‐Se) batteries. Herein, we report a rationally designed Ni‐bridged...
Breaking Solubility Limitation via Molecule Design to Build Localized Ultrahigh‐Concentration Electrolytes for Lithium Metal Batteries
Abstract The increase in salt concentration of electrolytes has been known as a simple but effective approach to restrain solvent activity and regulate solvation...
High Energy Density Heterostructured Sodium Layered Oxide Cathodes Enabled by Mechanical‐Chemical Coupling Effect
Abstract Designing cobalt‐free manganese‐based oxide cathode materials with high energy density and excellent stability is of great significance and a challenge....
The Weakened Super‐Exchange Interaction Realizes the Direct Regeneration of Spent Lithium‐lon Battery Cathodes
Abstract The direct regeneration of cathodes is an effective technique to address resource waste and environmental pollution caused by spent lithium‐ion batterie...
Inside Back Cover: Miniature Photoenzyme Enables Organelle‐Specific Cellular Control via Deboronative Hydroxylation (Angew. Chem. Int. Ed. 51/2025)
Azobenzene/Triptycene‐Based Cholesteric Liquid Crystal Dopants
Abstract The noncovalent interactions in cholesteric liquid crystals (CLCs) can be modulated using switchable chiral dopants resulting in the phototuning of the...
Elucidating Ligand‐Dependent Selectivities in Pd‐Catalyzed C–H Activations
Abstract Achieving regioselectivity in C–H activation remains a major challenge. Controlling or even reversing the regioisomeric outcome through the choice of ligand is even harder t...
Outside Back Cover: Artificial Decision Tree Guided Screening of Ultralong Room‐Temperature Phosphorescent Cocrystals with Locally Excited States (Angew. Chem. Int. Ed. 51/2025)
Accelerating Medicinal Chemistry: A C(sp <sup>3</sup> )‐Rich Fragment Toolbox for Redox‐Neutral Cross‐Coupling
Abstract The hit‐to‐lead phase of drug discovery is frequently bottlenecked by the time‐consuming, iterative synthesis of analogs, especially when incorporating...
A Multiply and Long‐Chain Branched Polyolefin with Low Density Polyethylene (LDPE)‐Like Properties Containing Two Types of Functional Groups
Abstract Low‐density polyethylene (LDPE) is an important material or plastic, which, unfortunately, is synthesized under very harsh conditions and challenging to recycle. We report h...
Targeting Aurora Kinases as Essential Cell‐Cycle Regulators to Deliver Multi‐Stage Antimalarials Against <i>Plasmodium Falciparum</i>
Abstract Kinases play critical roles in the development and adaptation of Plasmodium falciparum and present novel opportu...
Inside Front Cover: Harnessing Halogen Bonds in Porous Molecular Crystals for Efficient SF <sub>6</sub> /N <sub>2</sub> Separation (Angew. Chem. Int. Ed. 51/2025)
Spatially‐Directed C─C Coupling inside Three‐dimensional Metal‐organic Frameworks for CO <sub>2</sub> Electroreduction to C <sub>2</sub> Products
Abstract The CO 2 electroreduction reaction to fuels and chemicals is a promising strategy for storing intermittent energ...
Ultrawideband Emission of Bi <sup>3+</sup> Ions Spanning Visible to Near‐Infrared Spectral Regions (400 nm–1700 nm)
Abstract Although Bi 3+ ions exhibit exceptional luminescent properties and spectral tunability, their potential as activ...
Stabilizing Configurational Entropy in Spinel‐type High Entropy Oxides during Discharge–Charge by Overcoming Kinetic Sluggish Diffusion
Abstract Spinel‐type high entropy oxides (HEOs) have emerged as promising next‐generation lithium‐ion battery anodes owing to exceptional electrochemical perform...