Angewandte Chemie International Edition
Articles in this Issue
Stable BF <sub>2</sub> Boracycles as Versatile Reagents for Selective <i>Ortho</i> C–H Functionalization
Abstract The development of new boron reagents continues to play a crucial role in advancing modern organic synthesis, particularly in C–H functionalization and...
Hydrothermal Annealing of Hierarchical ZSM‐5 Zeolites Improves Catalytic Performance
Abstract Engineering next‐generation zeolite catalysts requires state‐of‐the‐art synthesis techniques to tailor the properties of materials along with robust methods to evaluate thei...
Synthesis of Axially Chiral Phenanthryl–Aryl Phosphines via Nickel‐Catalyzed Atroposelective [4 + 2] Cycloaddition with Broad Ligand Applications
Abstract Axially chiral biaryl phosphines and their oxides are indispensable ligands in asymmetric catalysis, enabling diverse enantioselective transformations. Here, we report the d...
Surface Avidity of Anionic Polypeptide Coatings on Layer‐by‐Layer Nanoparticles Target Cancer‐Associated Amino Acid Transporters
Abstract Tumor‐targeted drug delivery enhances therapeutic efficacy while minimizing toxicity. Layer‐by‐layer nanoparticles (LbL‐NPs) coated with anionic polypeptides selectively bin...
HALOM Method: An Efficient and Accurate Neutron Diffraction‐Independent Approach for Determining Hydrogen Locations in Metal Hydride Nanoclusters
Abstract Metal hydride nanoclusters play important roles in catalytic transformations and energy conversion. However, accurate localization of hydrogen atoms in...
Dynamic Protonation on an Amino‐Containing Quinone‐Covalent Organic Framework Enables Efficient Neutral Electrosynthesis of H <sub>2</sub> O <sub>2</sub>
Abstract The electrosynthesis of hydrogen peroxide (H 2 O 2 ) in neutral media is...
Biocompatible TADF Probes for Highly Multiplexed Fluorescence Lifetime Imaging
Abstract Fluorescence lifetime imaging microscopy (FLIM) is an optical imaging modality that can provide multiplexed readouts with remarkable sensitivity to cellular microenvironment...
Stereodivergent Synthesis of Three Contiguous Stereogenic Centers by Cu/Ir‐Catalyzed Borylallylation
Abstract Polyfunctional compounds bearing multiple stereogenic centers are synthetically valuable and important for complex molecule preparation. Herein, a Cu/Ir‐catalyzed borylallyl...
Programmable DNA Nanosprings with Tunable Chirality
Abstract Helical chiral structures are prevalent in nature and play vital roles in both biological and engineering systems. However, precise control over these structures at the nano...
Pickering Emulsion Interfaces Enhance Photocatalytic Selective Oxidation of Aromatic C─H Bonds
Abstract Solar‐driven photocatalysis provides a promising route for the green synthesis of high value‐added oxygenated chemicals through oxidization of C─H bonds. However, improving...
Combining ToF‐SIMS and Multivariate Analysis to Resolve Active Sites on Ni‐Based HER Catalysts
Abstract Unambiguous identification of active sites in heterogeneous catalysis remains a major challenge, particularly for materials with ultrathin, chemically m...
Inside Front Cover: Highly Efficient Construction and in Situ Post‐Assembly Modification of Multifunctional Metal–Organic Cages in Microdroplets (Angew. Chem. Int. Ed. 8/2026)
Experimental Isolation of Single Impact, Cumulative Energy, Aging, and Liquid‐Assisted Grinding Effects in Mechanochemical Reactions
Abstract Mechanochemical reactivity arises from a complex interplay between single impact energy, cumulative energy input, and secondary effects such as aging or...
A Crystalline Mono‐Coordinate Indium(I)‐Phosphaalkenyl
Abstract The synthesis of the mono‐coordinate indium(I) compound In[C(Ad)═PTer] (Ad = 1‐adamantyl, Ter = 2,6‐Dipp 2 ‐C...
Tuning pH for the Controlled Formation of Ultrasmall Nanoparticles with Direct Cytosolic Access
Abstract Direct cytosolic delivery of nanoparticles offers advantages by circumventing the endocytic pathway, thereby reducing associated intracellular trafficki...
Localized Active H* Enrichment by Cobalt Molecular Catalysts for Enhanced Electrocatalytic Nitrate Reduction
Abstract Electrochemical nitrate reduction (NO 3 − RR) offers a sustainable route for ammonia (NH...
Modulating Transient Solvation for Ultrahigh‐Rate Sodium Metal Batteries
Abstract Cation solvation in sodium battery electrolytes has been extensively studied in the bulk solution phase; however, its dynamic behavior under strong inte...
Single‐atom Electronic Bridge Facilitates Cascade Electron Transfer From Encapsulated Polyoxometalate to Metal‐Organic Framework for Efficient Photocatalytic CO <sub>2</sub> Conversion
Abstract The POM@MOF system, integrating the exceptional properties of polyoxometalates (POM) and metal‐organic frameworks (MOF), exhibits considerable catalytic...
Regulating Built‐in Electric Fields in Methylquinoline‐Derived Vinylene‐Linked Covalent Organic Frameworks for Enhanced Photocatalytic H <sub>2</sub> O <sub>2</sub> Production
Abstract The integration of functional moieties through robust covalent linkages is crucial for enhancing the stability, structural diversity, and photocatalytic...
Multicatalytic Access to Renewable Poly(Silyl Ether)s with Tunable Properties
Abstract The global reliance on petroleum‐based polymers presents urgent sustainability challenges. Addressing this issue, we present a novel one‐pot multicatalytic strategy for synt...
Chiroπ‐Extended Helitwistacene: Resolving the Planarity–Helicity Dilemma for Broadband Circularly Polarized Light Detection
Abstract Achieving broadband and high‐sensitivity circularly polarized light (CPL) detection with intrinsic organic semiconductors remains a fundamental challeng...
Sustaining Electrooxidation of Concentrated Thermo‐Sensitive Biomass Feedstocks by Temperature‐Mediated Kinetic and Interfacial Control
Abstract The inherent thermo‐sensitivity of biomass feedstocks often leads to side reactions (e.g., condensation) during biomass upgrading. Electrooxidation of b...
Cathodic Interfacial Oxidation‐Induced Rapid Synthesis of Nickel Phosphate Electrocatalyst from Wastewater for Acidic Nitrate‐to‐Ammonia Conversion
Abstract The electrochemical nitrate reduction reaction (NO 3 − RR) presents a promising strategy for...
Metal‐Mediated Nitrogen Doping of Carbon Supports Boosts Hydrogen Production from Ammonia
Abstract Ammonia is an attractive hydrogen carrier, yet its practical use is limited by the need for efficient catalytic decomposition. We demonstrate that in‐situ N‐doping of Ru nan...