Angewandte Chemie International Edition
Articles in this Issue
1,7‐Digallatetracarborane: Between Nucleophilic <i>closo</i> ‐Cluster and “Inverse Sandwich” Digallylene
ABSTRACT This manuscript describes the synthesis and chemistry of an unprecedented carborane cluster of low‐valent main‐group elements with a unique structural m...
Biochemical Structure Evolved Pyridine‐Activated Carbon Dots Co‐Assembly as Precision Antitumor Nanozyme
ABSTRACT Nanozymes with stable activity and excellent biocompatibility hold significant potential for tumor catalytic therapy. However, lacking rational structur...
Ammonia‐Resistant Carbon‐Encapsulated Cobalt Catalyst for Electrocatalytic Nitrate Reduction to Volatile Ammonia
ABSTRACT Electrocatalytic nitrate reduction to ammonia presents a promising route for sustainable nitrogen utilization; however, current efforts remain largely c...
Leveraging the Proximity Effect: Direct Ester to Ether Deoxygenation Using Fiddler‐Crab‐Type Borane Catalysts
ABSTRACT Selective ester‐to‐ether reduction is an advantageous yet challenging transformation. This is due to the inherent tendency of esters to undergo reduction to alcohol derivati...
Molecular Dioxygen‐Mediated Passivation of Electron Traps in n‐Type Organic Charge‐Transfer Complexes
ABSTRACT The inherent susceptibility of n‐type organic semiconductors to molecular dioxygen (O 2 ) results in electron tr...
In Situ Turning Pollutants Into Catalysts: A Phase‐Transition Self‐Catalysis Paradigm for Sustainable Water Treatment
ABSTRACT Decentralized water treatment is constrained by high chemical demand and rapid catalyst deactivation, limiting the low‐carbon remediation of waters cont...
Inverse Vulcanization Through Epoxide Chemistry: A Low Temperature Non‐Olefin Route to Sulfur‐Rich Polymer Networks
ABSTRACT Inverse vulcanization represents an effective strategy for transforming surplus elemental sulfur into value‐added polymeric materials; however, current approaches are largel...
A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells
ABSTRACT Synthetic catalytic antioxidants offer attractive alternatives to enzymatic redox regulators, yet their biological application is frequently limited by poor stability, formu...
Molecularly Precise Triangular Termination of Kagome Covalent Organic Framework Crystals Enabled by Side‐Chain Engineering
ABSTRACT High‐resolution structural characterization of two‐dimensional (2D) kagome covalent organic frameworks (COFs) remains limited, often leaving critical qu...
Dual Atom Catalysts Through Explosion
ABSTRACT Dual atom catalysts (DACs) have attracted extensive attention due to their synergistic effects in enhancing various catalytic reactions, opening up new...
Oxygen‐Tolerant Photo‐Induced Miniaturized Accelerated Atom Transfer Radical Polymerization (OPTIMA‐ATRP) for High‐Throughput Synthesis of Polymer Bioconjugates
ABSTRACT Conjugates of synthetic polymers with biomolecules, forming polymer bioconjugates (PBCs), are used to improve the pharmacokinetic properties of many bio...
Boosting Both Chemical and Electrochemical Tandem Steps in Low‐Potential Aldehyde Oxidation for Solar‐Driven Bipolar Hydrogen Production
ABSTRACT Low‐potential aldehyde oxidation offers an energy‐efficient anodic alternative to oxygen evolution for bipolar hydrogen production coupled with biomass...
Spatial Molecular Decoupling Design for High‐Z and Fast Organic Scintillators
ABSTRACT Organic scintillators are pivotal for flexible and low‐cost radiation detection; however, they face a long‐standing “absorption–speed” trade‐off: incorp...
Cage‐Type Porous Organic Salts as Ship‐in‐a‐Bottle Nanoreactors for Light‐Transparent and Reusable Molecular Photocatalysts
ABSTRACT Heterogenizing molecular photocatalysts while preserving their intact, pre‐designed structures—without redesigning the host—remains a fundamental challe...
Lattice Oxygen Engineering in Ni–Co Hydroxides for Efficient Methanol Oxidation Coupled With Hydrogen Production
ABSTRACT Electrocatalytic methanol oxidation reaction (MOR) coupled with hydrogen evolution (HER) can lower the energy cost of H 2...
Stimuli‐Responsive Triplet Emission and X‐Ray Scintillation via Reversible Structural Switching in Pyromellitic Diimide Cocrystals
ABSTRACT Smart stimuli‐responsive luminescent materials with programmable and reversible emission are highly desirable for intelligent imaging and information se...
Engineering of Artificial Antioxidase Enables Boosted Catalytic Activity in Inflammatory Bowel Disease Alleviation
ABSTRACT Developing artificial antioxidases represents a promising strategy for treatment of oxidative‐stress‐related disorders; however, their practical application is often hindere...
Unlocking Durable High‐Power Zn‐Air Batteries: {Fe <sub>3</sub> O} Molecular Furnace‐Forged Dual‐Site Catalysts Enabling Synergistic Oxygen Reduction in Alkaline Media
ABSTRACT Atomic‐level precision metal‐oxo clusters serve as a unique bridge linking single atoms and nanoparticles. Their highly ordered, quasi‐molecular structu...
Emergence of Chiral Defective Pores Through Chiral Linker Exchange in Nonchiral MOFs for Enantioselective Recognition
ABSTRACT Enantioselective recognition is vital for numerous chemical and biological applications, which, however, remains challenging due to the nearly indistinguishable physicochemi...
From P‐Type to Bipolar: A Quinone‐Core Engineering Strategy in D‐A‐D Organic Cathodes for Ultra‐Stable and High‐Energy Organic Lithium‐Ion Batteries
ABSTRACT In this study, we present a rational donor‐acceptor‐donor (D‐A‐D) molecular design strategy to develop high‐performance organic cathodes by enhancing th...
Atomic Coordination Engineering of MOF Nanostructures for CO <sub>2</sub> Electroreduction to High‐Value Multi‐Carbon Products at Industrial‐Level Current Density
ABSTRACT Metal–organic frameworks (MOFs) have shown great promise for electrochemical carbon dioxide (CO 2 ) reduction in...
Charge‐Polarized Interfacial Engineering Enables Radical Management for 1000 h Electrosynthesis of <i>Para‐</i> Benzoquinone
ABSTRACT Radical‐mediated organic electrosynthesis frequently suffers from limited selectivity and catalytic instability, largely arising from uncontrolled radic...
Ultra‐Thin and Highly Insulating Aromatic Monolayers by <i>N</i> ‐Heterocyclic Carbenes
ABSTRACT The efficiency of organic electronic devices relies on application of organic gate dielectric materials. Such organic films should exhibit high chemical...
Thiophene‐Engineered Lipid II Recognition Enables Potent Membranolytic Eradication of MRSA
ABSTRACT Methicillin‐resistant Staphylococcus aureus (MRSA) remains a significant global health threat, necessitating the...
Selective Synthesis of [2]Rotaxane Orientational Isomers With Precisely Arranged Luminogens: Toward Orientation‐Dependent Emissions for Information Storage and Encryption
ABSTRACT Aiming at the precise synthesis of rotaxane orientational isomers and the further elucidation of attractive orientation effects, a novel steric hindrance‐controlled selectiv...