Circulation
Articles in this Issue
Abstract 4345893: Serratia Marcescens Aortic Valve Endocarditis in Drug Use Disorder: A Case of Catastrophic Embolic Stroke and Hemorrhagic Transformation
Background: Nearly four centuries after Lazare Rivière’s first description of infective endocarditis—and over two centuries since septic embolization was recognized—a new epidemic...
Abstract 4373221: Clinical Implications of Elevated Lipoprotein(a) in the Absence of Significant Coronary Artery Stenosis
Background: Lipoprotein(a) [Lp(a)] has recently re-emerged as a biomarker of growing interest in the prognostic assessment of cardiovascular disease. However, prognostic evidence r...
Abstract 4368916: Dynamic Artificial Intelligence-enhanced Electrocardiographic Trajectories Outperform Single-Time-Point Screening for New-onset Heart Failure
Background: Predicting heart failure (HF) risk currently requires evaluating serum biomarkers or complex scores. AI-ECG model to define preclinical SHD on photos of ECGs represents...
Abstract 4371745: Association Between Gestational Weight Gain and Cardiac Biomarkers During Pregnancy
Background: Hypertensive disorders of pregnancy (HDP) are on the rise and are major contributors to adverse maternal and neonatal outcomes in the US. Cardiac and angiogenic biomark...
Abstract Sun1003: A recombinant protein oxygen carrier with reduced nitric oxide scavenging as a blood substitute for resuscitation
Background: Hemorrhagic shock remains a leading cause of preventable death. No artificial oxygen carrier based on hemoglobin or hemoproteins has been approved in the US as an alter...
Abstract 4360314: Association of Epicardial Adipose Tissue with Lipomatous Metaplasia and Ventricular Tachycardia Recurrence Following Ablation in Patients with Non-Ischemic Cardiomyopathy
Introduction: Patients with non-ischemic cardiomyopathy (NICM), present with complex intramural ventricular tachycardia (VT) circuitry and relatively high post-ablation recurrences...
Abstract 4346538: Safety and Effectiveness of Metabolic and Bariatric Procedures in Heart Failure: A Single-Center Cohort Study
Background: Metabolic and bariatric procedures are associated with reduced heart failure (HF) incidence among individuals with obesity, but studies evaluating their safety and effe...
Abstract 4348305: Pulmonary Hypertension is associated with higher In-Hospital Complications After WATCHMAN <sup>TM</sup> Implantation - A Nationwide Analysis of 198,000 Patients
Introduction: Left atrial appendage occlusion (WATCHMAN TM ) device has gained popularity in atrial fibrillation(AF) patients not suitable f...
Abstract 4368012: Regaining Ambulation as the Primary Goal in the Treatment of Chronic Limb-Threatening Ischemia
Background: The treatment goals for chronic limb-threatening ischemia (CLTI) include limb salvage, pain control, preservation of limb function, and wound healing. Patients with CLT...
Abstract 4366494: Navigating the Management of a Saphenous Vein Graft Aneurysm: A Case Report on Conservative Medical Management and Discussion of Treatment Options
Introduction: Saphenous vein graft (SVG) aneurysm is a rare but potentially serious late complication following coronary artery bypass grafting (CABG). The natural history is varia...
Abstract 4354457: Environmental Toxic Metal Exposure and Change in the Cardiac Biomarkers among US adults from 2015-2023: A Trend and Mixture Approach
Background: Toxic metal exposure is a growing public health concern due to its potential long-term effects on cardiovascular health. However, limited studies have evaluated the cum...
Abstract 4367135: Navigating the Anticoagulation Dilemma: The Impact of Anticoagulation Use on Outcomes and Healthcare Burden in Patients with Liver Cirrhosis and Co-Existing Atrial Fibrillation
Background: AF is a common comorbidity in patients with liver cirrhosis and may negatively impact both quality of life and prognosis. The management of AF in this population is com...
Abstract 4363014: Protein-Coding and Long Non-coding RNA Expression Signatures of Glycemic Traits
Introduction: Several glycemic traits indicate risk for type 2 diabetes (T2D). Although previous studies have identified many genes associated with glycemic traits, the underlying...
Abstract 4360153: Adverse Events and Outcomes Among Patients with Temporary Mechanical Circulatory Support Devices Placed at Referring Versus Hub Cardiogenic Shock Centers
Introduction: Temporary mechanical support (tMCS) devices (intra-aortic balloon pump [IABP], Impella CP, Impella 5.5) are commonly used in cardiogenic shock (CS) and are often plac...
Abstract 4360608: Ten-Year Trends in Complication Rates for Catheter Ablation of Atrial Fibrillation at an Academic Medical Center
Introduction: Catheter ablation is a commonly performed invasive procedure for management of atrial fibrillation (AF), and offers favorable cardiovascular outcomes and improved qua...
Abstract 4367183: Comparative Efficacy of High-Intensity Interval Training and Moderate-Intensity Continuous Training on Cardiovascular Outcomes in Adults: A Systematic Review and Meta-Analysis
Background: Exercise interventions are foundational in cardiovascular disease prevention and management. High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous T...
Abstract 4366607: Trends and patterns of concurrent contraceptive use with antihypertensive treatment in women using real-word data: Veteran Affairs Corporate Data Warehouse
Background: Due to teratogenic risks of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB), the current guideline recommends prescribing ACEI a...
Abstract 4346313: Unprocessed Red and Processed Meat and Alternative Protein Sources in Relation to Risk of Coronary Heart Disease: A Pooled Analysis of 1.7 million Participants
Background: The association between unprocessed red and processed meat intake and risk of coronary heart disease (CHD) remains controversial, particularly for unprocessed red meat....
Abstract 4366977: High Catastrophic Spending Among Younger Patients with CVD or Related Risk Factors
Introduction/Background: Since 2010, there has been an increase in cardiovascular disease (CVD) mortality among younger adults aged 25-64 years. There is growing concern that finan...
Abstract 4364556: Limited English Proficiency Is Linked to Gaps in Cardiovascular Follow-Up and Cardiac Comorbidity Capture
Introduction: Cardiovascular disease (CVD) disproportionately affects South Asians, with Nepali-speaking limited English proficiency (N-LEP) community at particularly high risk. In...
Abstract 4366533: York Trinity Score: An Anticipatory Risk Tool For Predicting Pathogenic Genotypes in Dilated Cardiomyopathy Phenotypes
Background: Genetic testing enables early identification, and risk stratification for both probands and at-risk family members with dilated cardiomyopathy (DCM). Although clinical...
Abstract 4369095: Baseline Left Atrial Strain as a Predictor of MACE, Heart Failure, Cardiotoxicity, and All-Cause Mortality in Lymphoma Patients Prior to Anthracycline Therapy
Background: Left atrial (LA) strain, measured by two-dimensional speckle tracking (2D-STE), has not been explored in lymphoma patients before anthracycline treatment as a prognosti...
Abstract 4368731: Episodic Periods of Growth Occur During Surveillance of Ascending Aortic Dilation
Background: There is limited data on how growth unfolds during surveillance of ascending aortic (AsAo) dilation. Most prior research has treated AsAo growth as a linear process, ca...
Abstract 4365055: Chronotype and Cardiovascular Disease Risk Factors among Middle-aged and Older Adults: A Mendelian Randomization Study
Introduction: Circadian misalignment is an emerging risk factor for poor cardiovascular health, and chronotype may reflect underlying circadian processes. While previous studies ha...
Abstract 4361329: Right Ventricular Remodeling Following 2 Years of High-Intensity Exercise Training in Sedentary Middle-Aged Adults
Background: During exercise, the right ventricle (RV) is subjected to proportionally greater increases in wall stress given its larger size, lower resting pressure and thinner wall...