Circulation

Subclinical Primary Aldosteronism and Major Adverse Cardiovascular Events: A Longitudinal Population-Based Cohort Study

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (M...

Subclinical Primary Aldosteronism: A Potential New Target in Cardiovascular Prevention?

Response by Bhatia and Tsimikas to Letter Regarding Article, “Independence of Lipoprotein(a) and Low-Density Lipoprotein Cholesterol–Medicated Cardiovascular Risk: A Participant-Level Meta-Analysis”

Letter by Sechi et al Regarding Article, “Independence of Lipoprotein(a) and Low-Density Lipoprotein Cholesterol–Medicated Cardiovascular Risk: A Participant-Level Meta-Analysis”

Targeting Calcium Regulation for Heart Failure and Arrhythmia Therapeutics: A Critical Review

Despite advances in pharmacologic and procedural therapies, heart failure (HF) and cardiac arrhythmias remain significant global health burdens, highlighting the urgent need for novel therapeutic stra...

Letter by White et al Regarding Article, “Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in the Management of Intermediate-Risk Pulmonary Embolism: Primary Results of the PEERLESS Randomized Controlled Trial”

Sudden Cardiac Arrest and Death Secondary to Congenital Coronary Artery Abnormalities in Young Competitive Athletes

Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry

BACKGROUND: Comprehensive knowledge of the clinical presentation, contemporary management, and outcomes on “all-comer” patients referred for mitral valve surgery (MVS) are critical to eval...

Response by Jaber et al to Letter Regarding Article, “Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in the Management of Intermediate-Risk Pulmonary Embolism: Primary Results of the PEERLESS Randomized Controlled Trial”

An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart Failure

BACKGROUND: Endogenous retroviruses (ERVs) occupy >8% of the human genome. Aberrant resurgence of ERVs has been implicated recently in several critical pathologies. However, the possibl...

Percutaneous Solutions for Tricuspid Regurgitation: Current Approved Options and Identifying Ideal Candidates