Circulation

Collateral Damage From Congenital Heart Surgery: Can Thymic Reimplantation Restore Immune Competence?

Clinical Practice of Surgical Treatment for Left-Sided Infective Endocarditis: Nationwide Data from the NIDUS Registry

BACKGROUND: Surgery is an essential treatment for selected patients with infective endocarditis (IE). Despite indications for surgery, not all patients undergo surgery. Most previo...

Surgery for Periprocedural Failure of Transcatheter Aortic Valve Replacement in the United States

Remote Ischemic Preconditioning in Noncardiac Surgery: Time to Reconsider or Refocus?

Long-Term Outcomes of Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation: A Propensity Analysis

BACKGROUND: The timing of surgery in asymptomatic severe mitral regurgitation remains controversial. This observational study sought to compare long-term outcomes of early surgery...

Introduction to the 2025 Cardiovascular Surgery–Themed Issue of <i>Circulation</i>

Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial

BACKGROUND: Wearable accelerometer devices measure free-living physical activity and sleep without relying on self-reports. Their utility to measure and compare recovery of physica...

Neurodevelopmental Outcomes in Early Adolescence: The Pediatric Heart Network’s Single Ventricle Reconstruction Trial

BACKGROUND: Neurodevelopmental and functional impairments are among the most consequential morbidities for survivors of hypoplastic left heart syndrome after staged single ventricl...

Expert Hands, Favorable Curves: Parsing the Evidence for Early Mitral Valve Repair

Effect of Remote Ischemic Preconditioning on Myocardial Injury in Noncardiac Surgery: The PRINCE Randomized Clinical Trial

BACKGROUND: Major noncardiac surgery is associated with high rates of postoperative myocardial injury and other complications. Remote ischemic preconditioning (RIPC) was reported t...

Current Status of Donation After Circulatory Determination of Death Heart Transplantation