Circulation
Articles in this Issue
Occupational Radiation Safety in Electrophysiology During Pregnancy: Evaluating Uterine Radiation Doses During Catheter Ablations and Device Implantations
Response by Rogers et al to Letter Regarding, “Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation”
Clinical Cardiology at the Crossroads: Perspectives on the Next Era at <i>Circulation</i>
Letter by Li et al Regarding Article, “Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation”
Cell Type–Specific Targeting of Different Smooth Muscle Cell Populations by Intersectional Genetics
BACKGROUND: The Cre/loxP recombination system is the main tool for cell type–specific lineage tracing and gene targeting. Currently available smooth muscle cell (SMC)–specific Cre...
Mechanical CPR Device Use and Cardiac Arrest Survival in EMS Agencies
BACKGROUND: Cardiopulmonary resuscitation (CPR) by health care responders is often suboptimal during out-of-hospital cardiac arrest (OHCA). Mechanical CPR devices have been promote...
The Postcardiac Arrest Inflammatory Response: Mechanisms and Therapeutic Targets
Postcardiac arrest syndrome is a complex multisystem disorder that evolves after return of spontaneous circulation and remains a major determinant of morbidity and mortality following out-of-hospital...
Subcutaneous Defibrillator Implantation With or Without Defibrillation Test: The Primary Results of the Randomized PRAETORIAN-DFT Trial
BACKGROUND: To improve survival of patients at risk of sudden cardiac death, subcutaneous implantable cardioverter defibrillators (S-ICDs) require optimal implant positioning for e...
Letter by Hu et al Regarding Article, “Cell-Specific Inducible Human APOL1 Risk Variant Expression in Mice Causes Hypertension and Renal Damage”
Perioperative Anemia and Patient Blood Management in Cardiac Surgery: A Scientific Statement From the American Heart Association
Perioperative anemia and red blood cell transfusions are important risk factors for morbidity and mortality in cardiac surgery. Preoperative anemia is common, with up to 50% of patients presenting for...
Response by Poudel and Susztak to Letter Regarding Article, “Cell-Specific Inducible Human APOL1 Risk Variant Expression in Mice Causes Hypertension and Renal Damage”
Heart Failure Occurring in the Perinatal Period: A Scientific Statement From the American Heart Association
Heart failure in the perinatal period remains ambiguous in definition and management despite its recognition as a unique disease state. The true incidence and prevalence of heart failure or left ventr...
HFpEF at the Splice Junction: A Thin Filament Mechanism of Diastolic Dysfunction
Alternative Splicing of TPM1 Mediated by SRPK3 Drives Cardiac Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, a condition characterized by impaired diastolic function and...