Circulation
Articles in this Issue
Abstract WE476: Distribution of Heart Failure Phenotypes by Age and Risk Factors
Background: Heart failure (HF) consists of two subtypes: heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) with hetero...
Abstract WE413: Predictive Performance of High-Sensitive C-Reactive Protein for Congestive Heart Failure: Post-Pandemic Analysis from NHANES 2021-2023
Introduction: High sensitivity C-reactive protein (hsCRP) has been widely used as a biomarker for cardiovascular risk stratification, including congestive heart failure (CHF). Howe...
Abstract TU163: Self-Measured Blood Pressure Monitoring Programs: Who are they good for?
Background: Self-Measured Blood Pressure (SMBP) Monitoring programs, which focus on teaching participants how to lower their BP through medication adherence and lifestyle changes,...
Abstract TU143: Indoor Radon Concentrations Are Associated With Incident Heart Failure Among Postmenopausal Women in the United States
Introduction: Emerging evidence links radon to prevalent risk factors for heart failure (HF), but little is known about the radon-HF association, itself....
Abstract WE549: Elemental Determinants of Cardiovascular Health: A Comprehensive Systematic Reviews and Meta-analyses of Observational Studies
Introduction: The biological balance of essential and harmful elements may represent a unifying pathway connecting environmental exposures, nutritional status, and cardiovascular d...
Abstract WE578: Early Bystander Resuscitation in the Workplace: Insights and Implications
Introduction: Out-of-hospital cardiac arrest (OCHA) remains a major burden, with an estimated incidence rate of around 50/100,000 person-year in Europe. Survival is still low and e...
Abstract TU266: Impact of Sleep Health on Mortality with Blood Pressure Variability and Race as Modifiers
Introduction: Multidimensional sleep health (MDSH) is an important but understudied determinant of mortality. We evaluated whether blood pressure variability (BPV) and race/ethnici...
Abstract TH948: Neighborhood problems, Identity Vitality Pathology, and Hypertension: A Race-Stratified Analysis
Introduction: Perceived neighborhood problems (PNP), including concerns about dilapidation and safety, have been linked to elevated hypertension risk through chronic stress pathway...
Abstract MPTU05: Explainable Stroke Risk Prediction Using Machine Learning and Large Language Models: Toward a Mobile-Enabled Clinical Decision Support Application
Background: Stroke is the second leading cause of death worldwide, accounting for approximately eleven percent of all deaths. Effective prevention depends on early identification o...
Abstract TH804: Understanding Cardiovascular Health Relevance Among Black Breast Cancer Survivors: Insights from the Exploring Cardiovascular Health Outcomes (ECHO) Project
Background: Black breast cancer survivors experience disproportionate cardiovascular disease (CVD)-related mortality compared to White survivors. Healthy lifestyle behaviors (e.g.,...
Abstract WE494: Sex-Based Disparities in Access and Psychosocial Health Among Adults with Premature Atherosclerotic Cardiovascular Disease
Introduction: Premature atherosclerotic cardiovascular disease (ASCVD) is a growing public health concern, particularly among women and socioeconomically vulnerable adults. Data on...
Abstract TU264: Smartphone-based Digital Phenotyping as a Scalable Approach to Measure Sleep Health in Emerging Adults
Background. Sleep is a key lifestyle factor for cardiometabolic health, but most epidemiologic studies rely on self-reported measures of sleep that are limited by recall bias and l...
Abstract TH889: Equol or equol producer - which is more important for cognition?
Background: Evidence from observational studies and short-duration randomized controlled trials (RCTs) suggests that equol, a gut-derived metabolite of soy isoflavone daidzein, may...
Abstract WE441: Progression and Risk of Type 2 Diabetes Mellitus According to Glycemic Phenotypes
Background: Heterogeneity in prediabetes (preDM) etiology may influence progression to type 2 diabetes mellitus (T2DM). Despite its clinical importance, longitudinal data on progre...
Abstract WE440: Non-Hispanic Black Adolescents Show Highest Prediabetes Prevalence Among Normal Weight Adolescents: Evidence from NHANES 2011–2020
Background: Prediabetes is often associated with obesity, yet prevalence among normal-weight adolescents remains underexplored. We hypothesized that racial disparities in prediabet...
Abstract WE565: Association of Stroke Subtypes With Sociodemographic, Modifiable, and Nonmodifiable Risk Factors in an Adult Asian Population: A Cross-Sectional Study
Introduction: Stroke incidence in Asia has nearly doubled over the past three decades, driven by demographic aging and lifestyle transitions. Yet, few studies have simultaneously e...
Abstract WE564: Identifying Sex Differences in Proteins Associated with Incident Ischemic Stroke in the UK Biobank
Background: Stroke remains one of the leading causes of death and morbidity worldwide, with a disproportionately higher burden among women. Recent advancements in omics, including...
Abstract WE421: Stable BMI From Young Adulthood to Midlife and Long-Term CKM Risk: The Coronary Artery Risk Development in Young Adults (CARDIA)
Background: Weight gain from young adulthood to midlife increases risk for metabolic syndrome and cardiovascular-kidney-metabolic (CKM) syndrome. We aimed to examine the longitudin...
Abstract TU216: Average Time to Hypertension Resolution Extends Beyond Two Weeks Postpartum After Hypertensive Disorders of Pregnancy
Introduction: Postpartum hypertension is a leading cause of severe maternal morbidity, yet most patients receive a single blood pressure (BP) check before the 6-week visit. Remote...
Abstract TU232: Psoriasis and Metabolic Syndrome in Men vs. Women: Insights from the National Health and Nutrition Examination Survey
Introduction and Objective: Psoriasis and metabolic syndrome (MetS) share complex inflammatory pathways, with unclear sex differences. We aimed to determine whether psoriasis is as...
Abstract 34: Quantifying Pulse Arrival Time Changes Across Sleep-Disordered Breathing Events: Insights from the MESA Sleep Study
Introduction: Pulse arrival time (PAT), the interval between cardiac electrical activity and peripheral pulse detection, reflects beat-to-beat vascular reactivity and autonomic ton...
Abstract TU255: Spatiotemporal Restructuring of United States Atherosclerosis Mortality and the Emerging Distribution of Cardiometabolic Risk
Background: Geographic disparities in atherosclerotic cardiovascular disease (ASCVD) mortality are longstanding, yet the pandemic disrupted cardiometabolic care and population risk...
Abstract TH958: Cardiovascular Risk Stratification Among United States Adults with Metabolic Dysfunction–Associated Steatotic Liver Disease
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) affects nearly one in three adults in the United States (US), and independently increases the risk of c...
Abstract TU118: Longitudinal Trajectories of Kidney Function in Heart Failure: A community study
Introduction: Chronic kidney disease affects nearly half of heart failure (HF) patients, underscoring the importance of regular kidney function monitoring. However, longitudinal tr...
Abstract WE415: Endothelial Dysfunction and Risk of Severe COVID-19 in a Biracial U.S. Cohort
Background: As of mid-2025, over 100 million people have had COVID-19 and in the United States, 1.2 million have died. Black Americans continue to experience higher rates of severe...