Circulation
Articles in this Issue
Time for Precision Medicine in Atrial Fibrillation Management? Not So Fast.
Letter by Chen Regarding Article, “Dose Response of Incidental Physical Activity Against Cardiovascular Events and Mortality”
Role of Circadian Health in Cardiometabolic Health and Disease Risk: A Scientific Statement From the American Heart Association
Cardiovascular and metabolic health are influenced by the circadian system, which regulates 24-hour rhythms across numerous physiologic processes. Disruptions to circadian rhythmicity can adversely af...
Biomarker-Based ABC-AF Risk Scores for Personalized Treatment to Reduce Stroke or Death in Atrial Fibrillation: A Registry-Based, Multicenter, Randomized, Controlled Study
BACKGROUND: The clinical use of risk scores to guide treatment decisions and improve clinical outcomes has rarely been prospectively evaluated. This study aimed to evaluate whether...
Single-Cell Splicing Isoform Atlas of the Adult Human Heart and Heart Failure
BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular netw...
Measure Twice, Cut Once!
Proteomic Signatures Involved in Cardiac Recovery After Mechanical Unloading
Clinical and Prognostic Significance of Anomalous Origin of a Coronary Artery in Adults
BACKGROUND: The clinical significance and outcome predictors of anomalous aortic origin of a coronary artery (AAOCA) in adults remains unclear. Therefore, the aim of this study was...
Combined Adaptive Immune Mechanisms Mediate Cardiac Injury After COVID-19 Vaccination
BACKGROUND: The COVID-19 pandemic, caused by SARS-CoV-2, has led to the first approval of mRNA vaccines in humans. By producing the full-length SARS-CoV-2 Spike protein, they induc...