Circulation
Articles in this Issue
A Crossroads in Cardiovascular Medicine: Progress and Barriers to Impact
During the past 75 years, advances in cardiovascular science and technology have significantly reduced morbidity and mortality. In 2012, Drs Nabel and Braunwald reviewed this progress in A...
Ivabradine in Patients Undergoing Noncardiac Surgery: A Randomized Controlled Trial
BACKGROUND: Perioperative beta blockade lowers heart rate and decreases the risk of myocardial infarction but increases the risk of hypotension, death, and stroke. Ivabradine, a se...
Response by Windfeld-Mathiasen et al to Letter Regarding Article, “Cardiovascular Disease in Anabolic Androgenic Steroid Users”
Clear as Mud: Determining the Stage of Prevention in Cardiovascular Disease
Response by Marcus to Letter Regarding Article, “Left Ventricular Entry to Reduce Brain Lesions During Catheter Ablation: A Randomized Trial”
PYGM Protects Against Myocardial Infarction by Enhancing Glycogenolysis and Facilitating Autophagic Flux
BACKGROUND: PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism. However, the role of PYG...
Sacubitril/Valsartan and Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy: The PRADA II Randomized Clinical Trial
BACKGROUND: Anthracycline- and trastuzumab-associated cardiotoxicity may lead to cardiac dysfunction and dose reduction or halt of potentially life-saving adjuvant cancer therapy. Whether...
Highlights From the <i>Circulation</i> Family of Journals
Letter by Liu and Huang Regarding Article, “Left Ventricular Entry to Reduce Brain Lesions During Catheter Ablation: A Randomized Trial”
Post–Myocardial Infarction Psychological Distress: A Scientific Statement From the American Heart Association
The importance of psychological distress in patients with cardiovascular disease is increasingly recognized as both a contributing factor to the development and progression of cardiovascular disease a...