Circulation

Letter by Fu et al Regarding Article, “Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction”

Microvascular Endothelial Cells License APS Vasculopathy Through YAP1- and CCN2-Mediated Signaling

BACKGROUND: Whereas antiphospholipid syndrome (APS) is best known for increasing the risk of macrovascular thrombosis, APS vasculopathy is characterized by the abnormal proliferati...

Correction to: Junctophilin-2 Regulates Store-Operated Calcium Entry to Drive Cardiac Fibroblast Activation, Fibrotic Repair, and Angiogenesis After Myocardial Infarction

Guidance for Incorporating FDA Processes into the ACC/AHA Clinical Practice Guideline Methodology: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Letter by Wang et al Regarding Article, “Impact of Heart Transplant Allocation Changes on Waitlist Mortality and Clinical Practice in Pediatric and Adult Patients With Congenital Heart Disease and Cardiomyopathy”

Response by Wooster et al to Letter Regarding Article, “Impact of Heart Transplant Allocation Changes on Waitlist Mortality and Clinical Practice in Pediatric and Adult Patients With Congenital Heart Disease and Cardiomyopathy”

Risks of Hyperkalemia With Potassium-Enriched Salt Substitute Among Patients Using Concomitant Blockade of the Renin-Angiotensin-Aldosterone System in the Salt Substitute and Stroke Study

Mind Over Matter: Cerebral Embolic Protection and Cognitive Function After TAVR

2025 ACC/AHA Clinical Practice Guidelines Core Principles and Development Process: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Global Rounds: United States

Impact of Cerebral Embolic Protection on Cognitive Function After Transcatheter Aortic Valve Implantation: Data From the BHF PROTECT-TAVI Randomized Trial

BACKGROUND: In addition to the risk of stroke, patients undergoing transcatheter aortic valve implantation (TAVI) are susceptible to a decline of neurocognitive function. This may...

The Transparent Reporting and Evaluation of Artificial Intelligence Models (TRUE-AIM) Report Card: A Quality Assurance Initiative of the American Heart Association Journals to Promote High-Quality, Reproducible Artificial Intelligence Research

Response by Yamada et al to Letter Regarding Article, “Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction”

Phenotypic Selectivity of Artificial Intelligence–Enhanced Electrocardiography in Cardiovascular Diagnosis and Risk Prediction

BACKGROUND: Artificial intelligence (AI)–enhanced ECG (AI-ECG) models are often designed to detect specific anatomical and functional cardiac abnormalities. Understanding the selec...

2025 AHA/ACC Statement on Cost/Value Methodology in Clinical Practice Guidelines (Update From 2014 Statement): A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

AIM The “2025 AHA/ACC Statement on Cost/Value Methodology in Clinical Practice Guidelines (Update From 2014 Statement)” describes a systematic approach for consistent implementatio...