Circulation
Articles in this Issue
Cardiac Intensive Care Unit Appropriate Patient Selection and Triage: A Scientific Statement From the American Heart Association
Cardiac intensive care units are specialized, high-acuity, and resource-intensive environments for the care of critically ill patients with cardiovascular disease. Over the past 60 years, medical and...
Letter by Badano et al Regarding Article, “Prognostic Value of Exercise Right Ventricular–Pulmonary Arterial Coupling in Primary Mitral Regurgitation”
Prevalence and Burden of Cardiac Amyloidosis in a Population-Based Autopsy Cohort
<i>Mir147</i> Limits the Contribution of Non-Foamy Macrophages to Atherosclerosis
BACKGROUND: Hypercholesterolemia and a high-fat diet promote 2 macrophage subtypes involved in atherosclerosis by inducing lipid droplet accumulation in foamy macrophages (FMs) and...
A Missed Signal and a Closed Pathway
Implications of Cranial Arterial Stenosis and Dolichoectasia for Cerebral Small-Vessel Disease Etiopathogenesis: Findings From a Prospective Mild Stroke Cohort
BACKGROUND: Stenosis and dolichoectasia of cranial arteries likely reflect distinct mechanisms. Their contributions to lacunar stroke and cerebral small-vessel disease (cSVD) remai...
The Heart’s Cipher, the Muscle’s Prophecy
Rethinking the Valsalva Maneuver During Resistance Exercise: Why Transmural Pressure Matters
Total Event Analysis in Cardiovascular Outcome Trials: Approaches and Interpretation
Olfactory Receptor Activation Reduces Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Remodeling
BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity. We aimed to target an o...
Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study
BACKGROUND: In stable coronary artery disease, the primary goal of percutaneous coronary intervention (PCI) is symptom relief. Fractional flow reserve (FFR)...