Circulation

Chordin-Like 1 mRNA Therapy for Acute Myocardial Infarction

The Diagnostic Challenge of Irregular Tachycardia Accompanied by Alternating Bundle Branch Block

The Role of the Collateral Circulation in Stable Angina: An Invasive Placebo-Controlled Study

BACKGROUND: Little correlation exists between the burden of ischemia and severity of angina in patients with stable coronary artery disease. This placebo-controlled, n-of-1 study i...

Response by Patel and Giugliano to Letter Regarding Article, “Efficacy and Safety of Non–Vitamin K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual Patient Data Meta-Analysis of 4 Randomized Clinical Trials of Patients With Atrial Fibrillation”

Transcatheter Aortic Valve Replacement With Local Anesthesia: When Less Is Less?

Characterizing the Immune Response in Pig-to-Human Heart Xenografts Using a Multimodal Diagnostic System

BACKGROUND: Porcine genome editing has revolutionized xenotransplantation, recently enabling the first pig-to-human heart xenotransplants. However, the xenoimmune response in heart...

Peri-Interventional Anesthesia Strategies for Transcatheter Aortic Valve Implantation: A Multicenter, Randomized, Controlled, Noninferiority Trial

BACKGROUND: Minimalist treatment strategies for transcatheter aortic valve implantation have been widely adopted because of continued procedural evolution, but large randomized tri...

When Diagnostic Criteria Redefine Disease: Lessons From the Padua and European Task Force Criteria

<i>IRF5</i> siRNA Nanoimmunotherapy: Restoring Macrophage Efferocytosis in Atherosclerosis

BACKGROUND: Impaired efferocytosis of macrophages within advanced atherosclerotic plaques leads to plaque deposition and rupture, ultimately resulting in atherothrombotic events. E...

Letter by Wu et al Regarding Article, “Bleeding and New Malignancy Diagnoses After Anticoagulation for Atrial Fibrillation: A Population-Based Cohort Study”

Response by Abdel-Qadir et al to Letter Regarding Article, “Bleeding and New Malignancy Diagnoses After Anticoagulation for Atrial Fibrillation: A Population-Based Cohort Study”

Letter by Hu et al Regarding Article, “Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual Patient Data Meta-Analysis of 4 Randomized Clinical Trials of Patients With Atrial Fibrillation”