Angewandte Chemie International Edition
Articles in this Issue
Iron Catalyzed Aryl–Aryl Kumada Cross‐Coupling: A Mechanistic and Computational Investigation
ABSTRACT The widespread use of precious metal catalysts in C–C bond‐forming reactions is increasingly challenged by concerns over toxicity, cost, and limited ava...
Visualizing and Quantifying microRNA‐Induced DNA Origami Separation at the Nanoscale
ABSTRACT Circulating microRNAs (miRNAs) are promising biomarkers for disease diagnosis, but their small size and instability hinder direct detection. The detection of miRNA using sol...
Decoding of Carbohydrates With Monosaccharide‐Level Resolution Using Tip‐Enhanced Raman Scattering
ABSTRACT We report a tip‐enhanced Raman spectroscopy (TERS) platform integrated with nanopillar‐assisted glycan trapping for high‐sensitivity, label‐free analysis of oligosaccharides...
Variation in the Singlet‐Triplet Energy Gap (Δ <i>E</i> <sub>ST</sub> ) Governs Multistep Thermal Responsive Photoluminescence in a Coordination Polymer Exhibiting Thermally Activated Delayed Fluorescence
ABSTRACT Negative thermal quenching (NTQ) materials remain scarce yet show promise for advanced applications, particularly in high‐power LEDs. Thermally activate...
Beyond the Sum of Its Parts: Alkyl‐Chain Engineering Unlocks Dopant‐Free Pyrene‐Based Antenna Molecules for Efficient Perovskite Solar Cells
ABSTRACT The pursuit of high‐performance, dopant‐free hole‐transporting materials (HTMs) is central to advancing the efficiency and stability of perovskite solar...
Dielectric‐Mediated Solvation Chemistry Unlock Ah‐Level Nail‐Penetration‐Resistant TiNb <sub>2</sub> O <sub>7</sub> Pouch Cells Operating at −60°C
ABSTRACT Ultra‐low‐temperature lithium‐ion batteries face challenges such as sluggish ion transport and uncontrolled dendrite growth. Herein, we propose in situ...
Machine‐Learning‐Assisted Screening of Electrolyte Additives for Aqueous Zinc‐Ion Batteries via a Molecular Descriptor Framework
ABSTRACT Additive engineering in aqueous zinc‐ion batteries is recognized as a key strategy for improving zinc anode stability. Nevertheless, the conventional tr...
Dissipatively Fueled Unidirectionally Communicating DNA Circuits That Control Biocatalysis
ABSTRACT Unlike most synthetic systems, life constantly reorganizes itself through the irreversible consumption of energy‐rich molecules and exhibits dynamic functionalities governed...
Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation
ABSTRACT We report the total synthesis of (−)‐owerreine, a bis‐indole alkaloid biosynthetically assembled from two deoxoapodine units. This a...
Direct Selection of Functional De Novo Macrocycles for Activation of <i>On‐Cellulo</i> Insulin Receptor
ABSTRACT The integration of mRNA display with genetic reprogramming, known as RaPID (Random non‐standard Peptides Integrated Discovery) system, has emerged as a...
A Single Alkyne‐Induced Core Isomerism in AuCu Clusters and Its Impact on Electronic Structure and Photothermal Response
ABSTRACT Ligands play a critical role in determining the geometric/electronic structures, and functional properties of metal clusters. While ligand exchange has...
Spin Channels Enable •H‐Triggered Ozone Activation for Self‐Accelerating Degradation of Reduced‐Sulfur Pollutant
ABSTRACT The practical application of catalytic ozonation for sulfurous volatile organic compounds (S‐VOCs) is limited by two key challenges: sluggish electron t...
Fluorine‐Mediated Engineering of Stable High‐Valence Single‐Atom Catalysts
ABSTRACT High‐valence single‐atom catalysts (HVSACs) generally exhibit superior catalytic activity owing to the fast electron transfer efficiency between HVSACs...
Positron Emission Tomography Imaging of Bacterial Infections With an Enterobactin Analog to Monitor Treatment Efficacy With a Catechol Antibiotic
ABSTRACT Positron emission tomography (PET) is an emerging tool under clinical investigation for the detection of bacterial infections. The ability to identify t...
In‐Situ Exsolving Silver Nano‐islands on High‐Entropy Perovskites for Energy‐Efficient Coupled Nitrate Reduction and Sulfide Oxidation
ABSTRACT Electrochemical nitrate reduction to ammonia (NO 3 RR) is a promising pathway for nitrogen recycling but remains...
Interfacial Hydration Engineering Synchronizes Hydrogen Evolution and Brucite Mineralization in Seawater Electrolysis
ABSTRACT Seawater electrolysis for production of brucite minerals and green H 2 encounters critical interfacial challenge...
Asymmetric Total Synthesis of (–)‐Verrucarol
ABSTRACT We disclose a concise, asymmetric synthesis of (−)‐verrucarol, the natural product precursor of bioactive trichothecene macrocycles including verrucarin...
All‐Cyclic‐Solvent Electrolyte Design Enables Ultra‐Low‐Temperature and Fast‐Charging Sodium‐Ion Batteries
ABSTRACT Conventional sodium‐ion battery (SIB) electrolytes are typically composed of mixed cyclic and linear carbonates, which face critical challenges at low t...
Ammonia‐Induced Metal–Organic Framework Membrane Pore Tuning for Hydrogen Separation
ABSTRACT Ammonia has attracted great attention as a key material for clean hydrogen production, such as the ammonia cracking process. Remaining trace ammonia in...
Nanoscale Plasmon–Exciton Strong Coupling‐Enhanced Photocatalysis: Role of Optical Dark States
ABSTRACT The interaction between plasmon and molecular transitions has emerged as a cornerstone in nanophotonics, offering fundamental insights and enabling plet...
Mitigating Lattice Distortion of Iron‐Sulfate Cathode via Quasi‐Perfect Ordered Motif for High‐Temperature Sodium‐Ion Batteries
ABSTRACT Alluaudite‐type Na 2+2x Fe 2−x (SO 4...
Counterion‐Engineered Water‐Stable Intravenously Administered Nanoparticles Enable In Vivo Reversal of Ticagrelor
ABSTRACT cis ‐Diols play critical roles in biological systems and form key structural motifs in many pharmaceuticals and vaccines. Specific i...
Nickel‐Catalyzed Enantioselective Direct Addition of 1,3‐Dienes to Aldehydes Enabled by Chiral Monodentate Diamidophosphite Ligands
ABSTRACT Enantioenriched dienols are important structural motifs in numerous bioactive compounds and serve as valuable intermediates in organic synthesis. Although several synthetic...
Charge‐Asymmetric Dual‐Cu Sites in a Metal‐Organic Framework Direct CO <sub>2</sub> Electroreduction to Ethanol
ABSTRACT The selective electrochemical CO 2 reduction reaction (CO 2 RR) to ethan...
Slowing Down Zinc Electrodeposition Kinetics Can Maximize and Compromise Anode Stability: How Slow Is Too Slow?
ABSTRACT Aqueous zinc metal batteries (AZMBs) are promising for next‐generation grid storage due to their low cost and intrinsic safety. However, their deploymen...