Angewandte Chemie International Edition
Articles in this Issue
Phototriggered Morphological and Compositional Change of UGGAA Repeat RNA Foci by Photoswitchable RNA‐Binding Ligand
ABSTRACT The expansion of specific repeat sequences causes dozens of heritable neuromuscular diseases, where expanded repeat RNAs play key roles in the pathogeni...
Control Strategies in Guanine Biocrystallization
ABSTRACT Highly reflective assemblies of guanine crystals generate a diverse array of optical phenomena in animals, from camouflage reflectors to image‐forming m...
Electron‐Efficient Formate Electrosynthesis from CO <sub>2</sub> and Biomass‐Derived Carbohydrates in a Zero‐Gap Electrolyzer
ABSTRACT Paired electrolysis is being actively developed for co‐producing valuable chemicals by leveraging electron transfer at bipolar electrodes. In electroche...
Radical‐Induced Hour‐Level Afterglow and Efficient Circularly Polarized Luminescence From Metal Halide Hybrid Glasses
ABSTRACT Molecular hybrid glasses have emerged as a fourth category in glass chemistry and materials, offering new possibilities beyond the synthesis limits and...
Pillar[6]arene Assemblies With Continuous Hydrophobic Grooves for Capture of π‐Conjugated Molecules
ABSTRACT Preorganization is a central principle in supramolecular chemistry, enabling selective molecular recognition through confined macrocyclic cavities. Extending this concept fr...
Engineering Bulk Compression and Surface Tension Strains Toward Anaerobic 5‐Hydroxymethylfurfural Photoconversion
ABSTRACT Achieving 2,5‐diformylfuran (DFF), a key green biomass plastic monomer, from conventional oxidation of 5‐hydroxymethylfurfural (HMF) often involves hars...
Trisoxazole Macrolides Potentiate the Microtubule Assembly and Antimitotic Activities of Taxanes
ABSTRACT Mycalolides are marine‐derived trisoxazole macrolides that exhibit potent actin‐depolymerizing activity and inhibit the proliferation, migration, and invasion of various can...
Redox‐Neutral Electrochemical <i>Cis</i> ‐Cyclopropanation of Alkenes With Sulfoxonium Ylides
ABSTRACT Herein, we report an efficient metal‐free and redox‐neutral electrochemical strategy for the cis ‐selective cycl...
A General Chemical Prepotassiation Strategy for Boosting the Zn‐Storage Performance of Polymorphic MnO <sub>2</sub> Cathodes
ABSTRACT Ion pre‐intercalation engineering, particularly using large‐radius K + cations, is pivotal to overcome the slugg...
pH‐Mediated Strong Metal‐Support Interaction Construction Through Dynamic Fermi Level Tuning
ABSTRACT The metal–support interface is central to governing catalytic transformations. While strong metal–support interaction (SMSI) is an established strategy to tailor the morphol...
Guest‐Enhanced Charge Separation in Porphyrin‐Based Double‐Cavity Metallacages for Visible‐Light‐Driven H <sub>2</sub> O <sub>2</sub> Production
ABSTRACT Hydrogen peroxide (H 2 O 2 ) is a versatile and green oxidant with wide...
Stabilizing Silver Single‐Atom Site via A Pore‐Confined Triphenylphosphine for CO <sub>2</sub> Conversion With High Substrate‐Specificity
ABSTRACT Ensuring the dispersion and anti‐aggregation of single‐atom sites under catalytic conditions remains a critical challenge in heterogeneous catalysis. He...
Trace Capture Hexafluoropropylene From Octafluoropropane via Complete Molecular Sieving Mechanism in a Highly Robust Metal−Organic Framework
ABSTRACT Deep removal of trace hexafluoropropylene (C 3 F 6 ) impurity from octaf...
Light‐Driven Competitive Selection in a Protein‐Catalyzed Dissipative Peptide Replication
ABSTRACT Theoretical models of prebiotic evolution propose that catalytic modulation can influence autocatalytic replication cycles. We hypothesized that a protein catalyst could cre...
Titanium Dinitrogen Complex Catalyzed Hydrophosphination Leveraging the N <sub>2</sub> ‐Unit Electron Reservoir
ABSTRACT Metal dinitrogen complexes, a prominent class of compounds in the mimic of Haber–Bosch NH 3 manufacture, have be...
Cyclic Photothermal‐Actuated Organic Crystals for Reconfigurable Optical Waveguides
ABSTRACT Photomechanically responsive crystals are emerging as intelligent materials for micro/nano manipulation, biomimetic machines, and adaptive systems. Howe...
In Situ Polymerization‐Driven Exfoliation of COFs: A Universal Strategy Toward High‐Performance Polymer Organic Cathodes
ABSTRACT Although covalent organic frameworks (COFs) are promising organic cathodes for lithium‐ion batteries, their compact layered bulk structure limits ion/el...
Self‐Immolative Nanotheranostics with Albumin‐Guided Tumor Targeting for Oxidative Stress‐Amplified Photodynamic Therapy
ABSTRACT Conventional photosensitizers suffer from intrinsic limitations in photodynamic therapy (PDT), including poor tumor selectivity, rapid systemic clearance, and inefficient re...
Tuning Terminal Groups of Hole‐Selective Materials to Suppress Nonradiative Recombination in Inverted Perovskite Solar Cells
ABSTRACT The performance of perovskite solar cells (PSCs) is critically constrained by nonradiative recombination at the perovskite/charge‐extraction interfaces,...
From Microscale to Nanoscale Shadow Electrochemiluminescence Microscopy
ABSTRACT Electrochemiluminescence (ECL) has emerged as a promising chemistry‐based imaging technique, yet its potential in optical nano‐imaging is still in the e...
Programmable Coacervate–Membrane Interactions Direct Internal and Collective Organization in Membranized Protocells
ABSTRACT In eukaryotic cells, membraneless organelles reorganize through regulated interactions with the plasma membrane and its underlying cortex, where cytoskeletal coupling and in...
Designing an Intergrowth‐Structure Li Ion‐Sieve Membrane for Long‐Term Stable Lithium Extraction
ABSTRACT Extracting lithium from seawater offers an additional Li source but is hindered by corrosion of Li 1.5 Al...
DNA Flap‐Mediated Control of Transcription for Programmable RNA Synthesis
ABSTRACT The growing success of RNA‐based therapeutics has emphasized the need for precise and programmable RNA synthesis platforms. T7 RNA polymerase (T7RP) is widely utilized for i...
Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry
ABSTRACT Myelin is the lipid‐rich membrane that surrounds neuronal axons and is essential for neurological function in vertebrates. The development of therapeutics that stimulate mye...
Chiral Nonlinear Optical Response in Achiral Quasi‐2D Perovskite Ferroelectric Featuring Unusually Large A‐Site Cation
ABSTRACT The exploration of 2D perovskites and chiral nonlinear optical materials has drawn significant interest due to their structural tunability and strong op...