Circulation
Articles in this Issue
Abstract 4354619: Impact of delayed diagnosis and suboptimal therapy on mortality in peripartum cardiomyopathy: findings from a multicenter prospective Tanzanian cohort.
Background: Sub-Saharan Africa bears the highest burden of peripartum cardiomyopathy (PPCM), where the condition is often underdiagnosed, misdiagnosed, undertreated, or inappropria...
Abstract 4365954: Outcomes Following Left Atrial Appendage Closure in Older Adults with Different Levels of Frailty
Background: Patients who are older and those that are frail are routinely referred for LAAC but may be at increased risk of adverse events following device implant. It is unclear h...
Abstract 4347629: Associations of Predicted CVD risk by the PREVENT Equation with AI-analyzed Coronary Atherosclerotic Plaque Characteristics
Background: The PREVENT equations estimates 10-year total CVD risk using clinical and laboratory data. Its association with coronary plaque morphology using coronary CT angiography...
Abstract 4365394: Impact of Temperature on the Incidence of Pulmonary Embolism: A Nationwide 10-Year Registry Study in Japan.
Background: Previous studies from Western countries have reported associations between environmental temperature and pulmonary embolism (PE), with increased risk in colder seasons....
Abstract 4357267: Systemic Inflammation Response Index Predicts 30-Day Mortality in Vietnamese Acute Heart Failure Patients
Introduction: Inflammation plays a important role in determining the prognosis of heart failure. Recent studies have demonstrated that both established and novel inflammatory bioma...
Abstract 4360835: A Retrospective Analysis of Papillary Muscle PVC Ablations and Postprocedural Outcomes
Background: Papillary Muscle (PM) related ventricular arrhythmia ablation is associated with lower acute success and suboptimal long-term outcomes due to complex anatomy, variable...
Abstract 4364857: Retrospective Analysis of the Accuracy and Clinical Utility of Predictive Artificial Intelligence in Cardiovascular Event Risk Assessment : PACE Study
Introduction: Predictive analytics powered by artificial intelligence (AI) and machine learning (ML) are revolutionizing cardiovascular risk assessment. Accurate prediction of low-...
Abstract 4365910: Depression and anxiety increase risk of chronic kidney disease via gain of CVD risk factors with an accentuated effect among women and non-white individuals
Background: Anxiety and depression accelerate the development of both cardiovascular risk factors and renal disease. It has been previously shown that CVD, its risk factors, and me...
Abstract 4343011: Echocardiographic AMYLI Score in Systemic Light-Chain Amyloidosis: Clinical Relevance and Risk Stratification
Background: While the AMYLoidosis Index (AMYLI) has been extensively utilized for screening cardiac amyloidosis (CA). However, the relationship between this parameter and amyloid b...
Abstract 4370247: Increased Left Ventricular Chamber Stiffness is Dissociated from Duration Dependent Increases in Interstitial Fibrosis Arising from Transient Hypertension in Swine
Objective: Swine subjected to 2-hour episodes of transient repetitive pressure overload (RPO) develop increased LV chamber stiffness and fibrosis after 2-weeks. These changes persi...
Abstract 4369896: Association Between Elevated Lipoprotein(a) and New-Onset Atrial Fibrillation: A Retrospective Analysis Using the TriNetX Research Network
Background: Atrial fibrillation (AF) is the most prevalent clinically encountered cardiac arrhythmia and is associated with an increased risk of heart failure, stroke, and all-caus...
Abstract 4373242: A Shocking Development After Peripheral Arterial Intervention
Background: Severely calcified lesions of the common femoral artery (CFA) and proximal superficial femoral artery (SFA) pose technical challenges for endovascular revascularization...
Abstract 4355972: Simulation Guided Aortic Valve Tracking and Strain Analysis in 4D Echocardiography
Background: Accurate tracking of the aortic valve in 4D transesophageal echocardiography (TEE) and subsequent leaflet strain measurement remain a challenge due to limited imaging t...
Abstract 4337225: Iron Deficiency And Quality Of Life In Patients With Chronic Heart Failure Treated With Liposomal Bivalent Stabilized Iron Sulfate
Introduction: Iron deficiency (ID), affecting up to 50% of Chronic Heart Failure (CHF) patients, is associated with higher mortality, worse symptoms, poorer quality of life and imp...
Abstract 4367780: Three-Year Outcomes after Deceased Cardiac Donor Heart Transplantation
Background: Deceased cardiac donor (DCD) heart transplantation has recently emerged as a safe and effective alternative to deceased brain donor (DBD) heart transplantation, with th...
Abstract 4360308: Clotting Catastrophe: Nonbacterial Thrombotic Endocarditis and Ischemic Fallout
We describe a 42-year-old female with a past medical history significant for antiphospholipid syndrome (APS) who presented as a transfer to our facility for evaluation of stroke-like symptoms. She exp...
Abstract 4368587: Obicetrapib in combination with ezetimibe on top of atorvastatin regresses atherosclerotic plaque lesions in APOE*3-Leiden.CETP mice
Background and aims: Regression of pre-existing atherosclerotic vascular disease has only been observed with aggressive lipid lowering therapy. Therefore, the aim of the present st...
Abstract 4358860: Comparative Efficacy and Safety of P2Y12 Inhibitors versus Aspirin Monotherapy Following Dual Antiplatelet Therapy in Patients undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis
Background: After percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) is typically followed by long-term aspirin monotherapy, but emerging evidence suggests...
Abstract 4366396: Adjusted Odds of In-Hospital Mortality by Surgical Timing and Procedure Type in Cardiac Transplant Recipients With Intestinal Ischemia: An NIS 2017–2022 Analysis
Background: Intestinal ischemia is an uncommon but life-threatening complication in heart transplant recipients. We evaluated the association between surgical intervention and in-h...
Abstract 4358377: Emerging Trends and Disparities in Heart Failure and Amyloidosis–Related Mortality Among U.S. Adults: A Nationwide Analysis from 1999 to 2023
Background: Heart failure (HF) remains a major contributor to morbidity and mortality in the United States (U.S.). Cardiac amyloidosis, a condition marked by the deposition of misf...
Abstract 4339093: UCHealth Healthy Hearts and Minds Family Program: Educating a family together to improve health outcomes
Introduction: For over 32 years, UCHealth Healthy Hearts and Minds (HHM) has provided heart health education and free cardiovascular risk screenings for students in Colorado. In th...
Abstract 4368878: Main Results of the Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure (COPILOT-HF) Program – A Pragmatic Randomized Study
Background: Despite strong guideline recommendations, GDMT adoption for heart failure remains low. We proposed that a remote pharmacist-led program using a non-licensed navigators...
Abstract 4354157: Increasing Risk of Fournier’s Gangrene and Other Rare Genital Infections in Heart Failure Patients with and without Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i): A Multicenter Cohort Study
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated significant improvements in heart failure (HF) outcomes; however, the Food and Drug Administratio...
Abstract 4340069: A National Analysis Of Heart Donation After Circulatory Death In The United States
Background: Heart transplantation (HTx) is the gold-standard therapy for refractory heart failure; however, this life-saving procedure remains greatly limited in the setting of an...
Abstract 4364627: Temporal Changes in High-Sensitivity C-Reactive Protein and Atherosclerotic Cardiovascular Disease in African Americans: The Jackson Heart Study
Background: African Americans (AAs) face higher mortality from atherosclerotic cardiovascular disease (ASCVD) than Whites. Inflammation plays a central role in atherosclerosis, yet...