Circulation
Articles in this Issue
Abstract 4370091: Dynamic Intraoperative Changes in Left Ventricular Global Longitudinal Strain are associated with Post Operative Atrial Fibrillation in Cardiothoracic Surgery
Background: Left ventricular (LV) global longitudinal strain (GLS) in an outpatient setting is an established marker of atrial fibrillation and adverse outcomes. However, the impli...
Abstract Sat1306: A 60-fold increase in SCA risk in the last kilometer of endurance races : Final sprint, fatal outcome.
Background: Sudden cardiac arrests (SCA) during endurance events remain rare but tragic. We hypothesized that an acceleration in the final kilometer of a race may lead to a higher...
Abstract 4361611: Prevalence of Masked Hypertension Assessed by Home Blood Pressure Monitoring According to AHA PREVENT Risk Estimation Among Japanese Outpatients
Background: Masked hypertension (MHT) is defined as high out-of-office blood pressure (BP) despite non-high office BP and is associated with incident cardiovascular disease (CVD)....
Abstract 4344198: Diagnostic efficacy of CT-FFR in coronary artery stenosis of varying severity
Background: Although fractional flow reserve (FFR) remains the gold standard for evaluating myocardial ischemia, its invasive nature limits widespread clinical adoption. CT-derived...
Abstract 4360462: Impact of lipoprotein(a) levels on subsequent cardiovascular events after endovascular therapy for femoropopliteal lesion
Background: Patients with peripheral arterial disease (PAD) have a poor prognosis due to the presence of multiple comorbidities. PAD is associated with a greater systemic atheroscl...
Abstract 4335927: Gene positive vs. gene negative clinical and structural outcomes in hypertrophic cardiomyopathy patients: a meta-analysis and systematic review
Background: Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease associated with increased risks of heart failure, sudden cardiac death (SCD), and stroke....
Abstract 4360036: Estrogen Deficiency by Ovariectomy Triggers Phenotypic Switching in Female Aortic Smooth Muscle Cells in Atherosclerosis
Background: The postmenopausal state increases atherosclerosis in women, yet the molecular and cellular mechanisms remain largely elusive. Smooth muscle cells (SMC) and their pheno...
Abstract 4366466: Clot or Not? Witnessing the Power of Multimodality Imaging
Background: Most left ventricular (LV) apical defects noted on transthoracic echocardiography (TTE) are presumed to be thrombi especially when an apical wall motion abnormality is...
Abstract 4368688: PERM1 Enhances Cardiac Contractility via Sarcomeric Metabolic Integration and Downregulation of MYBPC3
Background: Heart failure with reduced ejection fraction (HFrEF) affects over 3 million adults in the United States and is associated with high morbidity and mortality, with five-y...
Abstract 4364390: Development of an <i>In Vitro</i> Model of Functionally Innervated Human Myocardium
Introduction: Cardiac sympathetic innervation plays important roles in regulation of heart rate, contractility, and conduction, as well as postnatal maturation and injury response....
Abstract 4369749: Electronegative Lipoprotein Subfractions Modulate Inflammation and Viability in Monocytes and Endothelial cells
Background: Emerging evidence indicates that lipoprotein quality, more than quantity, drives atherogenesis. Lipoproteins can be classified into five subfractions by electronegativi...
Abstract 4371392: Primary Prevention ICD in Transthyretin Cardiac Amyloidosis and Reduced Ejection Fraction: A Propensity Score Matched Analysis
Background: Reduced ejection fraction in the setting of transthyretin cardiac amyloidosis (ATTR-CA) is associated with a poor prognosis. Based on current left ventricular ejection...
Abstract 4344683: Continuing versus Discontinuing Home Beta-blockers at Admission for Possible Sepsis: A Target Trial Emulation
Background: Beta-blockers (BB) are commonly prescribed to patients with chronic cardiovascular disease. Despite potential benefits in septic shock, BBs are often withheld at admiss...
Abstract 4361627: Circulating Long Non-Coding RNAs have Diagnostic and Risk Stratification Value with Mechanistic Roles in Heart Failure: a Meta-Analysis
Background: Long non-coding RNAs (lncRNAs) are emerging as a promising RNA class with clinical relevance in heart failure (HF). These RNA transcripts are over 200 nucleotides long...
Abstract 4365784: Computed Tomographic Images just after Successful Primary PCI Can Evaluate Symptomatic Transient ST Re-elevation Showed Transmural Myocardial Hemorrhag
Background: Reperfusion therapy such as percutaneous coronary intervention (PCI) is widely used in patients with acute myocardial infarction (AMI). While hemorrhagic transformation...
Abstract 4351129: Life’s Essential 8 Attenuates Premature Mortality Risk in Early-Onset Adult Type 2 Diabetes: Findings from Two Population-Based Studies in the U.S.
Background: Early-onset adult type 2 diabetes (T2D) is a more severe phenotype than later-onset T2D. We evaluated the extent to which Life’s Essential 8 (LE8) attenuates the risk o...
Abstract 4366778: Dyadic support promotes self-care and relationship quality in persons with hypertension
Introduction: Adequate self-care is associated with better health outcomes in those with hypertension (HTN). Interventions including care partners positively affect the health of t...
Abstract 4365278: Exploring Stress-Related Myocardial Injury in Diabetic Ketoacidosis: Risk, Prevalence, and Outcomes.
Background: Diabetic ketoacidosis (DKA) is a critical metabolic disorder that can trigger stress-related myocardial injury (SRMI), but national estimates of SRMI in DKA hospitaliza...
Abstract 4358240: Pulmonary Hypertension Associated with Rheumatic Heart Disease Presents a Major Unmet Disease Burden in Sub-Saharan Africa
Background: In rheumatic heart disease (RHD), post-streptococcal rheumatic fever causes valvular heart destruction leading to pulmonary hypertension (PH), a prognostic and potentia...
Abstract 4366460: Atrial Fibrillation Risk Estimated Using Electrocardiogram-based Artificial Intelligence Stratifies Incidence of Atrial Fibrillation-Related Stroke and Heart Failure
Background: Risk of future atrial fibrillation (AF) can be estimated using artificial intelligence (AI)-enabled electrocardiogram (ECG) analysis. However, it remains unknown whethe...
Abstract 4360598: A Retrospective Analysis of Chronic Kidney Disease and Arrhythmias-Related Mortality Among Adults in the United States (1999-2020): Insights into Disparities by Gender, Race/Ethnicity, and Geography
Introduction: Chronic kidney disease (CKD) is strongly linked to fatal cardiac arrhythmias and continues to be a significant health concern in the United States. CKD presents a com...
Abstract 4365018: Novel Use of KardiaMobile Device to Assess For Vector Suitability for Subcutaneous Implantable Cardioverter Defibrillator Implantation
Background: The subcutaneous implantable defibrillator (S-ICD) was developed to avoid lead related complications and systemic infections. Screening prior to implantation is critica...
Abstract 4359092: Characteristics and Long-Term Outcomes of Asymptomatic Patients with Hypertrophic Cardiomyopathy Undergoing Treadmill Stress Echocardiography
Background: In asymptomatic patients with hypertrophic cardiomyopathy (HCM), treadmill stress echocardiography (TSE) is performed to assess for functional capacity, ischemia, arrhy...
Abstract 4367008: Pulmonary Artery Pulsatility Index as Predictor of Right Heart Failure During Left Ventricular Unloading With Microaxial Flow Pump
Research Questions: Whether baseline pulmonary artery pulsatility index (PAPi) predicts right heart failure (RHF) in patients treated for cardiogenic shock with temporary left vent...
Abstract 4341180: Describing Burden For Transthyretin Amyloid Cardiomyopathy Patients And Their Caregivers In The United States: A Real-World Survey
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a rare form of heart failure. Symptoms can be burdensome and management often involves caregiver support. However, rea...