Circulation
Articles in this Issue
Abstract 4368736: Long-Term Clinical Outcomes in Patients with Heart Failure with Reduced Ejection Fraction and Mitral Regurgitation Undergoing MitraClip Therapy with Comorbid Malnutrition: A U.S. Population Based Cohort Study
Introduction: Growing evidence has highlighted the detrimental impact of malnutrition on outcomes among patients undergoing structural heart interventions. However, there is still...
Abstract Sun302: VASOPLEGIA IN PATIENTS TREATED WITH ECPR: RISK FACTORS, OUTCOMES AND TREATMENT STRATEGIES
Background: Vasoplegia is persistent hypotension or sustained vasopressor requirement despite adequate fluid resuscitation, typically in the setting of elevated cardiac output. Ext...
Abstract 4364476: Enhancing Sudden Arrhythmic Event Prediction in Patients with Coronary Artery Disease Using Cardiac MRI
Background: Sudden cardiac death (SCD) accounts for over 400,000 annual deaths in the United States with coronary artery disease (CAD) as the leading cause. Implantable cardioverte...
Abstract 4366768: National Outcomes of Concomitant Left Atrial Appendage Management and TAVR in Patients with Atrial Fibrillation
Introduction: Guideline recommendations for patients with atrial fibrillation undergoing cardiac surgery have considered atrial appendage management for the past decade. Recently,...
Abstract 4366444: Cardiovascular Risk Profile Across Age Groups: A Study of Asian, African, and Hispanic Communities in Philadelphia, PA
Background: Cardiovascular (CV) risk increases with age, yet data on age-related trends in underserved U.S. minority populations remain limited. This study evaluates differences in...
Abstract 4358585: Hemodynamic Subtypes of Pulmonary Hypertension Based on Right Heart Catheterization Data Predict Outcomes in ICI-Associated Myocarditis
Background: Pulmonary hypertension (PH) is a known complication in patients with cancer, arising from both therapies and malignancies. Immune checkpoint inhibitor (ICI)-associated...
Abstract 4364811: Single-Cell Transcriptomics Identified the pro-Pulmonary Arterial Hypertension Macrophages (PAH-M) Controlling smooth muscle proliferation and vascular remodeling via the IGF1 signaling
Rationale: Previously we identified a mouse model Tie2Cre -mediated disruption of Egln1 of Pulmonary...
Abstract 4370926: Systemic Inflammation In Overweight And Obese People: Does The Intensity Of Exercise Matter?
Introduction: Overweight and obesity are associated with chronic low-grade inflammation, and exercise has been shown to lower levels of inflammatory markers. In this study, we exam...
Abstract 4357659: A "non-muscle" alpha-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling
Background: The cellular unit of each heartbeat is the c ardiac...
Abstract 4368328: Oral anticoagulation for post-operative atrial fibrillation after valvular heart surgery: a population based study
Background: New onset post-operative atrial fibrillation is common after valvular heart surgery yet optimal oral anticoagulation (OAC) management in these patients is not known. He...
Abstract 4368976: Palliative Care in End-Stage Heart Failure: Impact on Readmissions, Mortality, and Healthcare Resources – A Propensity Score-Matched Analysis
Background: Palliative care is increasingly recognized for its role in advanced heart failure management, yet its real-world impact on healthcare utilization and clinical outcomes...
Abstract 4367080: Timeseries Foundation Model for Ventricular Tachycardia Detection in the Intensive Care Unit
Introduction: Ventricular tachycardia (VT) is a life-threatening clinical condition and common cause of cardiac arrest in the intensive care unit (ICU) setting. The current ICU-VT...
Abstract 4342198: Real-world Surveillance and Follow up for Incidentally Detected Ascending Thoracic Aortic Aneurysms on LDCT for Lung Cancer Screening
Background: Ascending thoracic aortic aneurysms (aTAAs) carry a risk of dissection and rupture, which increases with aTAA diameter. While the 2022 AHA/ACC guidelines recommend foll...
Abstract 4361551: Long term survival of older patients who receive cardiac resynchronization therapy devices with or without defibrillation therapy
Background: Cardiac resynchronization therapy (CRT) is an established treatment for heart failure (HF) patients that can be delivered either through a pacemaker (CRT-P) or a defibr...
Abstract 4369499: WAVE-AI: Wearable and Portable Vision-enabled ECG interpretation using AI
Background: Clinical 12-lead ECGs are used to diagnose a range of conditions, but the diagnostic utility of wearable and portable devices is limited to a limited number of rhythm d...
Abstract 4369930: Disparities in Editorial Leadership of Highly Cited Cardiology Journals by Gender and Country Income Classification
Background: Journal editors influence the visibility and direction of scientific research and should have adequate gender and geographic representation....
Abstract 4362958: RNS-Related Myocardial Injury: Sympathetic Activation-Induced Proinflammatory Bone Marrow Remodeling and Trained Immunity
An RNS mouse model was established using a “24-hour sleep deprivation and 48-hour recovery cycle” repeated for 5 cycles. RNS mice exhibited elevated peripheral inflammation and myocardial injury. Sing...
Abstract Or103: Automated cardiac arrest detection incorporated into a wristband: validation in patients with induced ventricular fibrillation
Background: Survival from unwitnessed out-of-hospital cardiac arrest is poor, often due to delayed activation of the emergency medical chain. Wearable technology capable of automat...
Abstract Sat107: Survival in Intubated Traumatic Brain Injury Patients Receiving Manual Versus Mechanical Ventilation in the Field: Does the Vent Help in EMS?
Background: The EMS TBI Guidelines support carefully controlling ventilation in the EMS management of intubated TBI patients [preventing hyperventilation (to enhance cerebral blood...
Abstract 4367533: The Impact of Prior Thoracic Irradiation on Outcomes of Patients Hospitalized for Acute Myocardial Infarction
Introduction: Thoracic radiotherapy plays a fundamental role in the treatment of various malignancies, including breast cancer, lung cancer, and lymphoma. However, thoracic irradia...
Abstract 4362112: Outcomes of Cardiac Implantable Electronic Device-Related Infective Endocarditis (CIED-IE) in Dialysis Patients
Introduction: End-stage kidney disease (ESKD) patients on dialysis are particularly vulnerable to developing cardiac implantable electronic device-related infective endocarditis (C...
Abstract 4366406: Etomidate Is Associated with Lower Odds of Early-Onset Hypotension and Hypoxemia but Not Cardiac Arrest Compared to Ketamine in Endotracheal Intubation: A Meta-Analysis of Their Comparative Hemodynamic Outcomes
Introduction: Etomidate and ketamine are both widely used in endotracheal intubation (ETI), a critical procedure in emergency and intensive care settings often associated with hemo...
Abstract 4357266: Anomalous Origins: Hereditary Transthyretin Cardiac Amyloidosis Mimicking Ischemia in a Patient with Congenital Coronary Anomalies
Background: The management of coronary artery anomalies (CAA) remains a clinical dilemma as the prognostic implications are poorly understood. The presence of ischemia and CAA does...
Abstract 4367903: Prognostic Value of Carbohydrate Antigen 125 in Chronic Heart Failure: A Systematic Review and Meta-Analysis
Background: Chronic heart failure (CHF) is a complex clinical syndrome associated with high morbidity and mortality. Recent studies have explored a potential novel biomarker, carbo...
Abstract 4341577: Brugada or STEMI? -Brugada-like ECG caused by ischemia of large conus branch veiled the ST-elevation of inferior myocardial infarction-
Introduction: Conus branch ischemia is rare; however, when present, it typically induces Brugada-like ST-elevation in the precordial leads of 12-lead electrocardiography (ECG), mim...