Circulation
Articles in this Issue
Abstract 4364214: Aspirin Use in Men is Independently Associated with Slower Growth Rate of Ascending Thoracic Aortic Aneurysms
Introduction: Aspirin has been associated with slower progression and rupture prevention of abdominal aortic aneurysms. However, its effect on ascending thoracic aortic aneurysms (...
Abstract 4367343: Transgender Male and Gender Non-Binary/Genderqueer Patients are Less Likely to Receive Guideline-Indicated Cardiovascular Care than Cisgender Patients: A Nationwide Study
Introduction: People identifying as transgender, non-binary, or genderqueer are at higher risk for cardiovascular disease. Additionally, bias and overt discrimination limit care ac...
Abstract 4367503: Left ventricular remodeling index to predict ventricular tachyarrhythmia in dilated cardiomyopathy with ejection fraction <35%
Background: Myocardial fibrosis assessed by cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) imaging has emerged as a powerful predictor for sudden cardiac d...
Abstract 4368624: Genetic Testing Outcomes in Hypertrophic and Dilated Cardiomyopathy: A Five-Year Retrospective Review
Cardiomyopathies (CM) are rare, inherited heart diseases. Major types include dilated, hypertrophic, restrictive, and arrhythmogenic right ventricular cardiomyopathy. Hypertrophic cardiomyopathy is th...
Abstract 4369359: Updated Cost-Effectiveness of ICD Implantation for Primary Prevention of Arrhythmic Death with Contemporary Guideline-Directed Medical Therapy
Introduction: Advances in guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) over the past two decades have substantially reduced th...
Abstract 4366419: GLP-1 Receptor Agonist Semaglutide Improves Hepatic Metabolism and Reverses Hepatic Steatosis Independent of Weight Loss in Cardiometabolic HFpEF
Background: The GLP-1 receptor agonist, semaglutide, was shown to be beneficial in obese (STEP HFpEF) and diabetic (STEP HFpEF DM) patients suffering from heart failure with preser...
Abstract 4339496: Human induced pluripotent stem cell derived nanovesicles for the treatment of ischemic limb diseases
Background: Critical limb ischemia is a severe stage of peripheral artery disease. It causes claudication, ischemic pain, and ulceration. It is a serious condition that increases r...
Abstract 4339302: Symptomatic Recurrence of Subaortic Membrane- An Obstructive Challenge
Description of Case: A 42-year-old female with a history of sub-aortic membrane resection 10 years ago presented to the cardiology clinic with complaints of exertional dyspnea and...
Abstract 4364895: Automated External White Adipose Tissue Segmentation Using Routine Magnetic Resonance Imaging and Artificial Intelligence
Introduction: Quantifying adiposity, a key biomarker of metabolic health, typically requires imaging that involves radiation, high costs, and manual effort. We developed an AI fram...
Abstract 4363188: Impact of Atrial Fibrillation in Patients with Severe Mitral Regurgitation Undergoing Transcatheter Edge-To-Edge Repair
Background: Atrial fibrillation (AF) and mitral regurgitation (MR) are closely linked, and one may worsen the other. Objec...
Abstract 4366491: Machine Learning Analysis of EMS Data leads to Accurate and Timely Stroke and Severe Stroke Detection
Background: Stroke is a leading cause of long-term disability and death, where time to treatment drastically affects outcomes. Rapid detection and transport to appropriate stroke c...
Abstract 4371057: Preoperative Anion Gap to Bicarbonate Ratio is Associated with Elevated Risk of Delirium After Cardiac Surgery
Background: Delirium, a common and multifactorial complication after cardiac surgery, is influenced by several factors including inflammation, metabolic disturbances, and cerebral...
Abstract 4359856: Heart and Lung Transplantation by Citizenship Status: Achieving Equitable Outcomes Despite Inequitable Access
Introduction: Non-U.S. citizens, including undocumented immigrants and international patients, face substantial barriers to heart and lung transplantation in the U.S., including la...
Abstract 4363318: Characteristics of Blue Zones and Their Association with Longevity: Analysis in the Women’s Health Initiative
Background: Nine lifestyle characteristics have been identified across Blue Zones - 5 regions of the world noted for their longevity - but these factors have yet to be empirically...
Abstract 4357018: Evaluation of genetic testing and its clinical indications in early-onset atrial fibrillation
Background: The genetic basis of atrial fibrillation (AF) remains incompletely understood. While next-generation sequencing (NGS) can detect various rare variants, the identificati...
Abstract 4343027: Comparison study of Minimally invasive surgical thoracoscopic ablation and hybrid ablation vs Catheter Ablation in treatment of AF patients : Systematic review and meta-analysis
Background: Atrial fibrillation is the most common cardiac arrhythmia, affecting about 33.5 million patients. Its incidence varies extensively across countries, and was observed mo...
Abstract 4357187: Multi-system Thromboembolism: A Case of Concurrent Pulmonary, Myocardial, and Abdominal Embolism.
Introduction: Multisystem thromboembolism is a rare, life-threatening condition that requires rapid identification and intervention. In the presence of a right-to-left shunt, parad...
Abstract 4365653: Variation in Use of Pulmonary Hypertension Therapies among Acute Care Cardiology Units – a Pediatric Acute Care Cardiology Collaborative Registry Evaluation
Introduction/Background: Pulmonary hypertension (PH) is a frequent complication of congenital heart disease (CHD) that is estimated to account for 30-50% of pediatric group 1 PH pa...
Abstract 4357666: Definitive Therapeutic Efficacy of Colchicine for Cardiovascular Disease A Systematic Review and Meta-Analysis in 37,812 Patients
Background and Aims: Cardiovascular disease is a global health concern requiring effective prevention. Colchicine has gained interest for reducing cardiovascular events in high-ris...
Abstract 4344008: Overcoming cardiovascular nonresponse to exercise in healthy, older adults.
Introduction: Routine physical activity reduces the risk of death and cardiometabolic diseases and increases cardiovascular fitness measured as peak oxygen uptake (VO...
Abstract 4357087: Brown Adipose Tissue-Heart Crosstalk Attenuates Adverse Cardiac Remodeling
Abstract: BACKGROUND: While brown adipose tissue (BAT) is recognized to attenuate the incidence of cardiovascular disease, its specific role in adverse cardiac remodeling and relat...
Abstract 4359985: Uncovering True Severity: The Role of Dobutamine Stress Echocardiogram in Paradoxical Low Gradient Aortic Stenosis
Background: In patients with paradoxical low-gradient severe aortic stenosis (AS) based on aortic valve area (AVA) at rest (<1cm2) and normal left ventricular ejection fraction...
Abstract 4343703: A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb
Background: Cardiovascular-Kidney-metabolic (CKM) syndrome is a public health problem in the US and results in premature CVD at a relatively pr...
Abstract 4365520: Effects of Gender on Outcomes in Acute Type A Aortic Dissection
Objective: Although gender-related disparities in cardiovascular surgery have been investigated extensively in the past decades, knowledge about the impact of gender on outcomes af...
Abstract 4369181: Extracellular Volume and T1 Mapping by Cardiac MRI Predict Outcomes in HFpEF: A Systematic Review and Meta-Analysis
Background: Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all cases of heart failure (HF) and carries a similar burden as heart failure with re...