Circulation
Articles in this Issue
Abstract 4362813: Survival Benefit of Beta-Adrenergic Suppression Following Lung Transplantation
Introduction: Long-term survival following lung transplant surgery (LT) presents an ongoing challenge, with a five-year survival rate of 55%. Furthermore, adverse LT outcomes are l...
Abstract 4367194: Sex-Specific Outcomes in Heart Failure with Mildly Reduced Ejection Fraction: A Real-World Analysis
Background: Heart failure with mildly reduced ejection fraction (HFmrEF), defined by a left ventricular ejection fraction (LVEF) of 41–49%, is a growing clinical entity. However, l...
Abstract 4348064: Meta-Analysis of Outcomes Following Lead Extraction for Cardiac Implantable Electronic Device-Related Infections in Patients with Left Ventricular Assist Devices
There is a class I recommendation for lead extraction in cardiac implantable electronic device (CIED) infections. However, in patients supported by left ventricular assist devices (LVAD) the calculus...
Abstract 4367193: Exercise Training Does Not Alter Early Diastolic Function in Patients with Heart Failure with Preserved Ejection Fraction
Introduction: Low fitness and exaggerated left ventricular (LV) filling pressures are defining features of Heart Failure with Preserved Ejection (HFpEF). The augmented LV filling p...
Abstract Sun703: Adapting Chest Compressions to Variable Chest Dynamics in Out-of-Hospital CPR
Introduction: According to resuscitation guidelines and research literature, chest compression (CC) depth, rate and impulsiveness are related to CPR quality. However, physiological...
Abstract 4368244: The effect of LCZ696 on cardiac function and structure in a novel, shortened cardio-metabolic mouse model of heart failure with preserved ejection fraction
Background: Current preclinical murine models for heart failure with preserved ejection fraction (HFpEF) require prolonged modeling periods, pose significant challenges to fast scr...
Abstract 4358989: The Effect of Produce Prescription Dose Upon Benefit Redemption, Food Security, and Produce Consumption: a Randomized Trial
Background: Produce prescription programs (PRx) have the potential to enhance diet quality and improve food security. However, key implementation questions remain....
Abstract 4368956: 2-Deoxyuridine Associates with Recurrent Coronary Events
Background: Altered metabolic pathways underlie atherosclerosis and acute coronary events. Objectives:...
Abstract 4371618: Integrated Assessment of Lipoprotein(a) and ECG Changes to Predict Paroxysmal Atrial Fibrillation Recurrence After Ablation: A Retrospective Study of 2,356 Patients
Background: Elevated lipoprotein(a) [Lp(a)] levels have been associated with cardiovascular risk, but their prognostic value in atrial fibrillation (AF) recurrence following radiof...
Abstract 4370993: A Silent Storm: Incidental Discovery of IVC and Right Atrium Thrombus in a Patient with Uterine Stromal Sarcoma
Introduction: Patients with malignancy, especially high-grade uterine sarcomas, are at elevated risk for venous thromboembolism (VTE), including deep vein thrombosis (DVT), pulmona...
Abstract 4366314: Outcomes of patients with Cardiac Sarcoidosis (CS) implanted with an implantable cardiac defibrillator (ICD).
Background: We aimed to evaluate the outcomes of patients with confirmed and possible cardiac sarcoidosis who had an ICD implant and identify predictors of ventricular arrhythmias...
Abstract 4371248: Sodium-Glucose Cotransporter 2 Inhibitors in Frail Octogenarian Population with Heart Failure- A Real-World Study
Introduction: Sodium-Glucose Cotransporter 2 (SGLT-2) inhibitors have shown mortality and morbidity benefit in patients with heart failure with reduced ejection fraction (HFrEF). H...
Abstract 4339564: Evidence shows comparable efficacy of dual therapy with ticagrelor and aspirin versus monotherapy in peripheral arterial disease: A systematic review and meta-analysis of 1,702 patients
Peripheral artery disease (PAD) increases the risk of cardiovascular events, such as stroke and myocardial infarction. Antiplatelet therapy, particularly aspirin, has been essential in the management...
Abstract 4365500: Improved Shared Decision-Making on Stroke and Bleeding Risks in Atrial Fibrillation: A Mixed-Methods Study of a Tablet-Based Risk Visualization Tool
Background: Oral anticoagulants (OACs) remain a cornerstone for preventing ischemic stroke in patients with atrial fibrillation (AF). However, patients often have limited understan...
Abstract 4367046: Impact of Area Deprivation Index on Gaps in Care for Young Adults with Congenital Heart Disease
Introduction: Neighborhood socioeconomic deprivation has been previously linked with inferior health outcomes such as mortality and hospitalizations for adults with congenital hear...
Abstract 4366475: Sex Differences in Left Ventricular Remodeling after Transcatheter Mitral Valve Repair
Introduction: Left ventricular (LV) reverse remodeling after mitral transcatheter edge-to-edge repair (MTEER) is a well-observed phenomenon. However, there is limited and variable...
Abstract 4370525: Vitamin D Deficiency Increases Mortality and Neurological Complications Following Subarachnoid Hemorrhage
Introduction/Background: Vitamin D deficiency has been associated with various cardiovascular and neurological conditions, but its impact on outcomes following subarachnoid hemorrh...
Abstract 4367167: Magnet Hospital Designation is Associated with Lower In-Hospital Mortality Among Acute Decompensated Heart Failure Patients: A Multi-center, Multi-level Analysis
Background: Magnet® designated hospitals demonstrate excellence in nursing practice. Acute decompensated heart failure (ADHF) is a critical condition characterized by the sudden wo...
Abstract 4366717: Mechanisms for the association between social determinants of health and sleep-related functional outcomes among rural adults with cardiovascular diseases
Background: Social determinants of health (SDOH)—the conditions in which people are born, grow, live, work, and age—strongly influence health. Rural adults with cardiovascular dise...
Abstract 4368481: Digital Transformation of Echocardiographic Data: Accuracy and Innovation in 3D Hemodynamic Simulation for Atrial Septal Defect Assessment
Background: Two-dimensional transthoracic echocardiography (2D TTE) remains the primary imaging modality in congenital heart disease (CHD) due to its accessibility, low cost, real-...
Abstract 4373593: Effect of Sodium-glucose cotransporter 2 inhibitors and Sacubitril/Valsartan on Mortality and Emergency Admission free Survival in 1,072 Patients with Congenital Heart Disease
Background: Heart failure is the leading cause of death in patients with congenital heart disease (CHD). We used longitudinal health insurance data and robust statistical methods t...
Abstract 4368231: Trimethylamine N-oxide Promotes Atrial Arrhythmia Susceptibility via Neuroglial IL-1β-Driven Inflammatory Activation of the Left Stellate Ganglion
Dietary choline intake has been epidemiologically linked to an increased risk of atrial fibrillation (AF); however, the mechanistic underpinnings of this association remain poorly understood. Among th...
Abstract 4353230: The prognostic accuracy of three-dimensional echocardiography in patients with pre-capillary pulmonary hypertension
Aims: To investigate the prognostic accuracy of three-dimensional echocardiographic (3DE) right ventricular (RV) data and compare it with that of risk stratification based on 2015...
Abstract Sun307: Spinal Cord Injury and Neurological Outcome in a 24-Hour Survival Rat Model of 8-Minute Ventricular Fibrillation Cardiac Arrest Resuscitated With eCPR and 12-Hour Hypothermic Temperature Control
Introduction: The impact of global ischemia and reperfusion on the brain in resuscitation animal models is well investigated whereas the spinal cord and its protection are rarely r...
Abstract 4371609: Predictors of Risk Perception Accuracy in Reproductive-Age Women: Implications for Targeted Risk Communication
Background: Accurate cardiovascular risk perception is essential for preventive behavior adoption, yet predictors of risk perception accuracy in reproductive-age women remain poorl...