Circulation
Articles in this Issue
Abstract 4367226: Mortality Trends in Takotsubo Patients in Rural and Urban Communities
Background: Recent studies have demonstrated increased mortality rates in Takotsubo syndrome (TTS) based on the social determinants of health including racial disparities and media...
Abstract 4369312: NOX2 Knockdown Attenuates Atrial Fibrillation-Induced Senescence Marker Upregulation and Atrial Fibrillation Burden in Canine Atria
Background: Atrial fibrillation (AF) is associated with aging and increased expression of senescence-associated secretory phenotype (SASP) markers. It remains unclear whether AF di...
Abstract 4364311: Forecasting Mortality from Congenital Heart Disease Across the Lifespan: Trend Analysis from 1999 to 2020 and Projections to 2030 Using SARIMA Modeling.
Introduction: Congenital Heart Disease (CHD) is the most common birth defect and is significantly associated with mortality in children. This study explores trends in CHD-related m...
Abstract 4369439: Concurrent Quadruple Valve Replacement and Patent Foramen Ovale Closure for Carcinoid Heart Disease
Introduction: Carcinoid cancer is a rare neuroendocrine tumor (NET) secreting vasoactive substances. Case Presentation:...
Abstract 4367189: Clinical Efficacy of Telemedicine vs Standard Outpatient Management for Heart Failure: A Systematic Review and Meta-Analysis
Background: Telemedicine (TM) modalities—home tele-monitoring and structured telephone support—are proposed to improve outcomes in heart failure (HF), yet pooled effects remain inc...
Abstract 4364557: Fibroblast Progenitor Cells Contribute to Vasculogenesis During Regenerative Wound Healing
Background: The goal of tissue regeneration is to restore structure and function. In adult regenerative wound healing, dermal fibroblasts exhibit multipotency and can be reprogramm...
Abstract Sun103: Capnoraphy and Thoracic Impedance Ventilation Quality During Cardiac Resuscitation
Background: End-Tidal Capnography (EtCO 2 ) is the primary ventilation bio-signal in out-of-hospital cardiac arrest (OHCA). Transthoracic Im...
Abstract 4359485: Impact of Social Determinants of Health on Emergency Department Use Following Congenital Heart Surgery
Background: Emergency department utilization is common for patients with congenital heart disease (CHD) after congenital heart surgery. Children with CHD who present to the ED are...
Abstract 4357726: Targeted Therapy, Collateral Damage: Navigating Acute Coronary Syndrome in the Era of Ponatinib
A 58-year-old male with history of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) on ponatinib, and hypertension was admitted to the Oncology service with three days of fever...
Abstract 4339719: Impact of Tricuspid Regurgitation Severity on Clinical Outcomes Following Mitral Valve Interventions: A Meta-Analysis
Bachground: Functional tricuspid regurgitation (TR) frequently develops secondary to mitral valve disease, but its impact on clinical outcomes after mitral valve interventions are...
Abstract 4370627: Impacts of Parental Protein Malnutrition on Cardiac and Renal Development
Background: Poor maternal nutrition during pregnancy raises the risk of various adult-onset diseases in offspring, including cardiovascular, kidney dysfunction, and hypertension. H...
Abstract 4364906: Intravascular Lithotripsy Versus Rotational Atherectomy in Calcified Coronary Artery Disease: A Systematic Review and Meta-Analysis
Background: Traditional plaque-modification strategies such as rotational atherectomy (RA) have long served as a cornerstone in managing these lesions, despite limitations includin...
Abstract 4364987: Cardiovascular Adverse Events in BTKi-Treated Patients: A Propensity-Matched Study of Ibrutinib and Acalabrutinib
Introduction: Bruton’s tyrosine kinase inhibitors (BTKis) have transformed the management of B-cell malignancies but have varying cardiovascular toxicity profiles. We evaluated and...
Abstract 4365686: Outcomes of Supraclavicular Access in Temporary Pacemaker Implantation
Background: Temporary pacemakers (TPM) are often placed using femoral, jugular, or subclavian veins, but these approaches have risks like pneumothorax or lead dislodgement. The sup...
Abstract 4369583: Is It Safe to Discontinue Oral Anticoagulation After Catheter Ablation for Atrial Fibrillation? A Systematic Review and Meta-Analysis
Introduction: Catheter ablation is a well-established rhythm control strategy for atrial fibrillation (AF), demonstrating superior efficacy compared to antiarrhythmic drug therapy....
Abstract 4366553: Temporal response to treatment of CL-HFS diet in respect to MASH liver development
Introduction: Liver dysfunction contributes to cardiovascular disease (CVD) and metabolic dysfunction-associated steatohepatitis (MASH), characterized by fat accumulation, inflamma...
Abstract 4368923: Impact of GLP-1 Receptor Agonist and SGLT2 Inhibitor Combination Therapy on Cardiovascular Events in Hospitalized Diabetic Patients: A National Inpatient Sample Analysis
Background: GLP-1 receptor agonists (GLP-1 RAs) and sodium-glucose co-transporter-2 inhibitors (SGLT2is) have both shown cardiovascular benefits in type 2 diabetes mellitus (T2DM)....
Abstract 4369318: Left Ventricular Chamber Stiffness Progressively Increases Despite the Normalization of Blood Pressure After Brief Repetitive Left Ventricular Pressure Overload
Background: Sustained systolic hypertension can produce LV hypertrophy and interstitial fibrosis that leads to increased LV stiffness and the development of HFpEF. Nevertheless, th...
Abstract 4364338: Protein Tyrosine Phosphatase 1B Inhibition Rescues From Metabolic Dysfunction-Induced Cardiomyopathy And HFpEF
Background: Metabolic cardiomyopathy and heart failure with preserved ejection fraction (HFpEF) are major contributors to cardiac-related hospitalization and mortality. Despite adv...
Abstract 4369470: Safety and Efficacy of PCSK9 Inhibitors in Ischemic Heart Disease: An Updated Systemic Review and Meta-Analysis
Introduction: Ischemic heart disease (IHD) remains a leading global cause of morbidity and mortality despite advances in therapies. Lowering low-density lipoprotein cholesterol (LD...
Abstract 4362326: Impact of Early Reimplantation after Transvenous Lead Extraction of Infected Cardiac Implantable Electronic Device
Background: Transvenous lead extraction (TLE) is the standard of care for cardiac implantable electronic device (CIED) infections. Data regarding the optimal timing of CIED reimpla...
Abstract 4364550: Increase in Acute Myocardial Infarction Hospitalization and In-Hospital Mortality Rates During the COVID-19 Pandemic in California from 2016 to 2022
Background: The COVID-19 pandemic has significantly impacted healthcare systems and patient behaviors, potentially affecting cardiovascular disease prevalence and outcomes. This st...
Abstract 4369027: Isolated Right-Sided Heart Failure as the First Manifestation of a Pelvic Neuroendocrine Tumor: A Rare Case of Carcinoid Heart Disease in a female with no prior diagnosis of carcinoid syndrome
Introduction: Carcinoid heart disease (CHD), a rare cardiac manifestation of neuroendocrine tumors (NETs), predominantly affects right-sided valves due to fibrotic plaque depositio...
Abstract 4371152: Individual Social Determinants of Health, Area-Level Social Vulnerability and Incidence of Major Adverse Cardiovascular Events in a Primary Prevention Population: Real-World Evidence from The Houston Methodist CV Learning Health System (HM-CV-LHS) Registry
Introduction: Social determinants of health (SDOH) are key drivers of individual and population cardiovascular health. However, the relative effects of individual-level social dete...
Abstract 4367172: Efficacy of eHealth-Enabled versus Traditional Cardiac Rehabilitation: A Systematic Review and Meta-Analysis of 26 Randomized Controlled Trials
Background: Cardiac rehabilitation (CR) is a key component of secondary prevention in cardiovascular disease, improving quality of life and reducing events. However, participation...