Circulation
Articles in this Issue
Abstract 4368298: AI-Enhanced Automated Vascular Risk Assessment Using Multi-Territory Non-Coronary Imaging: A Systematic Review
Introduction: Standard cardiovascular testing relies primarily on medical history and coronary imaging, which may fail to detect the full extent of systemic vascular disease. Using...
Abstract 4365903: Higher Social Deprivation Index and Social Vulnerability Index Are Not Associated With Increased Peripheral Artery Disease–Related Mortality in The United States.
Background: Peripheral artery disease (PAD) continues to pose a significant public health burden in the United States (U.S.), contributing to increased morbidity, functional declin...
Abstract 4365112: Association of County-Level Labor Force Participation During Childhood and Cardiovascular Health in Young Adulthood
Background: Socioeconomic status (SES) is associated with worse cardiovascular health (CVH) and poorer health outcomes. Stable, full-time employment is one protective SES factor am...
Abstract 4368226: Global Trends in Cerebrovascular Disease-Related Mortality from 2000 to 2019: A World Health Organization Global Health Estimates Study
Background: Cerebrovascular diseases are one of the leading causes of death globally. Understanding the mortality trend is essential to design targeted intervention....
Abstract 4366384: Premature Discontinuation or Downtitration of Medical Therapy for Heart Failure After Changes in Kidney Function
Background: Despite the known benefits of guideline directed medical therapy (GDMT) for Heart Failure (HF), implementation of these therapies is often limited by concern for worsen...
Abstract 4366004: Placental Epigenetic Signatures of Prenatal Pesticide Exposure and Fetal Growth: Insights into Cardiometabolic Programming
Prenatal exposure to pesticides has been linked to disrupted fetal growth, which contributes to cardiometabolic disease risk. The placenta, as the maternal–fetal interface, undergoes extensive DNA met...
Abstract 4370821: The Impact of Septal Myectomy on Ventricular Arrhythmias in Hypertrophic Obstructive Cardiomyopathy: Insights from a High-Volume Cardiac MRI/HoCM Center
Background: Ventricular arrhythmia is an important factor in determining the risk of sudden cardiac death (SCD) in patients with hypertrophic obstructive cardiomyopathy (HoCM). Des...
Abstract 4359789: Clinical Outcomes of Optical Coherence Tomography–Guided versus Angiography-Guided PCI in Complex Coronary Lesions: A Meta-Analysis of Randomized Controlled Trials
Background: Optical coherence tomography (OCT) offers superior imaging resolution compared to conventional angiography and has been linked to improved outcomes in percutaneous coro...
Abstract 4365944: Impact of Weekend Admission on In-Hospital Outcomes of Endovascular Thrombectomy for Acute Ischemic Stroke: National Inpatient Sample Analysis
Background: Disparities in hospital staffing and resource availability during weekends may delay treatment and worsen clinical outcomes for patients with acute ischemic stroke (AIS...
Abstract 4364981: Trends and Disparities in Cerebrovascular Disease and Depression-Related Mortality in the United States (1999–2019): A Nationwide Analysis
Background: Clinical depression is associated with an increased risk of cerebrovascular accidents. Despite this risk, the mortality trends related to both depression and cerebrovas...
Abstract 4359535: Is it safe to use exercise stress testing as a single screening strategy for coronary artery disease in masters athletes?
Background: Coronary artery disease (CAD) is responsible for approximately 610,000 deaths annually. In 2022, an estimated 315 million individuals globally had prevalent CAD (95% UI...
Abstract 4362459: Serum levels of IgG4 as a preoperative indicator of IgG4-related abdominal aortic aneurysm
Background: Immunoglobulin G4-related disease (IgG4-RD) has systemic inflammatory fibrous lesions characterized by elevated serum IgG4 and infiltration of IgG4-positive plasmacytes...
Abstract 4357473: Prevalence and Recovery of Arrhythmia-Induced Cardiomyopathy in Patients with Newly Diagnosed Heart Failure Using a Wearable Defibrillator: A Real-World Cohort Study
Background: Arrhythmia-induced cardiomyopathy (AIC) is a potentially reversible cause of heart failure triggered by sustained arrhythmias. Its true real-world prevalence and clinic...
Abstract Sun1407: Inhaled Nitric Oxide Facilitates VA-ECMO Weaning in ECPELLA-Supported Patients with Precapillary Pulmonary Hypertension
Background: Combined support with a micro-axial flow pump (mAFP) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) (ECPELLA) is effective for refractory biventricular...
Abstract 4357295: High-Resolution Optical Mapping of hiPSC Cardiac Grafts in Swine Reveals Reentry and Automaticity as Potential Arrhythmia Mechanisms at the Host-Graft Interface
Introduction: Recent therapies implanting cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) have shown improved cardiac performance. The implanted tissue...
Abstract 4364115: Circulating PCSK9 as an Independent Prognostic Marker in High-Risk Coronary Multi-Vessel Disease: Evidence from a Multicenter Cohort Study
Background: Although PCSK9 inhibitors have demonstrated significant cardiovascular benefits, the prognostic role of circulating PCSK9 levels in patients with coronary multi-vessel...
Abstract 4373662: Rising Mortality from Chronic Kidney Disease with Comorbid Atrial Fibrillation in the United States: Demographic and Geographic Disparities (1999–2020)
Background: Atrial fibrillation (AF) frequently co-occurs with chronic kidney disease (CKD), contributing to worse outcomes in patients with advanced renal impairment. However, nat...
Abstract 4365950: Renal Klotho Targeting Myocardial IQGAP1 Regulation of Mitochondrial Damage and PANoptosis in Heart Failure
Background: Heart failure following myocardial infarction (post-MI HF) is a leading cause of morbidity and mortality worldwide. The presence of chronic kidney disease (CKD) often e...
Abstract 4363392: Peripheral Artery Disease and Post-Transplant Outcomes: Disease Burden Overcomes Distribution
Introduction: Peripheral artery disease (PAD) is a known risk factor for adverse cardiovascular outcomes and has historically been viewed as a relative contraindication to heart tr...
Abstract 4367521: Comparative Reperfusion Strategies in Patients with Veno-Arterial Extracorporeal Membrane Oxygenator Supported Pulmonary Embolism
Introduction: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly employed for cardiopulmonary support in cases of pulmonary embolism associated with hemody...
Abstract 4369474: Right Heart Catheterization in Patients with Cardiogenic Shock: A Worldwide Retrospective Cohort Study.
Introduction/Aims: Despite initial popularity, the usefulness of right heart catheterization (RHC) is long debated, with cardiogenic shock (CS) patients largely overlooked until re...
Abstract 4364280: Routine Use of Epicardial Atrial Pacing After Cardiac Surgery: Impact on In-Hospital Outcomes in a Community Hospital in Argentina
Introduction: Epicardial atrial pacing (EAP) is selectively used in cardiac surgery, but its routine postoperative application lacks robust supporting evidence....
Abstract 4365487: A Novel Classification of Heart Failure Derived from the Nationwide JROADHF Cohort Using Unsupervised Machine Learning
Introduction/Background: Heart failure (HF) care is still steered almost solely by left-ventricular ejection fraction (LVEF), yet outcomes remain sub-optimal, suggesting that the H...
Abstract 4369161: Use of AI in young cases of sudden cardiac arrest: Implications for treatments and neuropsychiatric pathologies.
Background: Sudden Cardiac Arrest (SCA) in young adults is a significant public health issue, with survival rates often less than 15%. In young adults, most SCA arise from patients...
Abstract 4367739: Silent Infiltration: Asymptomatic Cardiac Metastasis from Primary Lung Adenocarcinoma
Introduction: Cardiac metastases are more common than primary cardiac tumors and typically indicate poor prognosis. Lung, breast, melanoma, and lymphoma are the most frequent prima...