Circulation
Articles in this Issue
Abstract 4368291: A Rare Case of Haemophilus influenzae Endocarditis Leading to Valvular Cardiogenic Shock and Acute Respiratory Distress Syndrome
Introduction: Haemophilus influenzae is a rare cause of native valve infective endocarditis. We present a case of double valve endocarditis with initial focal n...
Abstract 4367239: Combination of High-Sensitive Troponin I and NT-proBNP for Mortality Risk Stratification in Hospitalized COVID-19 Across Pandemic Waves: Pooled Analysis from COVID-MI Registry Cohort-1 and Cohort-2
Background: Hospitalized Coronavirus disease 2019 (COVID-19) patients continue to experience high mortality, and while either high-sensitive troponin I (HsTnI) or N-terminal pro-B-...
Abstract 4363253: Peri-Procedural Complications in Transcatheter Aortic Valve Replacement with Amyloidosis: Insight from the National Inpatient Sample 2016-2019
Background: Transcatheter aortic valve replacement (TAVR) is rapidly becoming commonplace for severe symptomatic aortic stenosis (AS). As amyloidosis is becoming more frequently di...
Abstract 4343852: Pressure-adjusted Heart Rate by Echocardiography and Mortality in the Cardiac Intensive Care Unit
Introduction: Pressure-adjusted heart rate (PAHR) provides an integrated assessment of hemodynamic decompensation in critically ill patients....
Abstract 4368671: Urokinase Plasminogen Activator Receptor Expression in Failing Human Hearts and Its Interaction with Integrins
Introduction: Elevated circulating levels of solubilised urokinase plasminogen activator receptor (uPAR) predict adverse cardiovascular outcomes; however, its role in cardiac patho...
Abstract 4370457: Dilated Cardiomyopathy and Heart Failure in an Infant due to an Intronic Deletion Disrupting <i>TAZ</i> Splicing
Background: Barth syndrome (BS) is an X-linked recessive disorder caused by loss of function mutations in the TAZ gene. BS is characterized...
Abstract 4369149: National Patterns of Use of Electronic Health Record–Integrated Artificial Intelligence Predictive Models at US Hospitals and their Performance on Key Cardiovascular Outcomes
Background: While predictive models that leverage artificial intelligence (AI) have been proposed to improve clinical outcomes, it is essential to examine the current landscape of...
Abstract 4370212: Nationwide Trends and Disparities in Endocarditis-Related Mortality by Sex and Age Group Among U.S. Adults: A 25-Year Analysis, 1999–2023
Background: Endocarditis continues to be a significant contributor to cardiovascular mortality in the United States (U.S.). Although national efforts have led to improvements in ov...
Abstract 4367306: Non-invasive Diastolic Stress Testing in a Large Observational Cohort Study: Insights from the Dallas Heart Study
Introduction: Despite its increasing prevalence and significant morbidity/mortality in the aging population, heart failure with preserved ejection fraction (HFpEF) remains challeng...
Abstract 4361939: Impact of Atrial Fibrillation Ablation on Patients with Amyloidosis: A Real-World Propensity Score-Matched Study
Introduction: Patients with amyloidosis and atrial fibrillation experienced poorer outcomes. The effect of atrial ablation on patients diagnosed with amyloidosis remains unclear....
Abstract 4343575: Expedited outpatient work-up is safe for evaluation of some emergency department patients with chest pain
Background: Chest pain is a common presenting symptom in the emergency departments (EDs). Safe and timely outpatient evaluation is reasonable for some patients without acute corona...
Abstract 4371988: Cardiovascular Outcomes of Oral Incretin-Based Therapies in Type 2 Diabetes: A Systematic Review and Meta-Analysis of 62,821 Patients
Background: While injectable GLP-1 receptor agonists like semaglutide have demonstrated clear cardiovascular benefits in type 2 diabetes, the role of oral incretin-based therapies,...
Abstract 4365065: Prevalence of Latent Rheumatic Heart Disease in Brazilian Public Schools: Results 10 Years After Implementation of a Screening Program
Introduction: Echocardiographic (echo) screening has emerged as an useful tool for identifying latent Rheumatic Heart Disease (RHD), surpassing clinical exam in accuracy. Diagnosti...
Abstract 4369012: Differential changes in Atrial vs. Ventricular excitation-contraction coupling in transgenic mice expressing an autosomal dominant mutation in the human αB-crystallin gene (hR120GCryAB)
Background: Transgenic mice expressing the human R120G mutant αB-crystallin (hR120GCryAB)—an autosomal dominant mutation—develop progressive cardiomyopathy, with atrial remodeling...
Abstract 4358099: Cardiology Conferences Have a Higher Research Yield Than Other Subspecialties: A 10-Year Follow-Up Study of AHA and ACC Annual Meetings
Introduction: Leading cardiology conferences like the American Heart Association (AHA) and American College of Cardiology (ACC) Annual Meetings are vital platforms for presenting n...
Abstract 4365293: Nighttime Light Pollution Associates with Adverse Cardiovascular Events via a Mechanism Involving Heightened Stress-Related Neural Activity and Atherosclerotic Inflammation
Background: Artificial light at night (ALAN) is ubiquitous in modern cities and linked to cardiometabolic disorders, yet its independent contribution to cardiovascular disease (CVD...
Abstract 4370579: Chronic Kidney Disease is Associated With Decreased Survival In Patients with Cardiogenic Shock and Tricuspid Regurgitation
Introduction: Chronic kidney disease (CKD) often coexists with and complicates congestive heart failure (CHF). In addition, tricuspid regurgitation (TR) is both a cause and a conse...
Abstract Or112: Brain Oxygen and ICP Optimization in Severe post Cardiac Arrest (BOOSCA)
Background: Cerebral edema after resuscitation from cardiac arrest (CA) may elevate intracranial pressure (ICP) and lower brain tissue oxygen (PbtO2) levels, causing secondary brai...
Abstract 4370620: Association of Ramus Intermedius Variant with Greater Coronary Plaque and Stenosis Burden
Background: The ramus intermedius (RI) is a variant artery arising from the trifurcation of the left main (LM) coronary artery. While RI has been found to be associated with greate...
Abstract 4371064: Sex, Race, and Insurance Status Independently Predict Inhospital outcomes in Post-CABG Atrial Fibrillation:A 5 year Analysis of latest NIS Data
Background: Postoperative atrial fibrillation (AF) significantly increases cardiac arrest risk and mortality following coronary artery bypass grafting (CABG). While clinical predic...
Abstract 4370938: Predicted Prosthesis–Patient Mismatch and Mortality Following Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis
Background: Prosthesis–patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR) is most often evaluated using the measured indexed effective orifice area (EOAi) o...
Abstract 4352617: High Visceral-to-Subcutaneous Fat Ratio is Correlated with Increased Cardiovascular Events in Patients with a Low Lean Body Mass Index Suspected of Coronary Artery Disease
Introduction: Abdominal fat distribution, quantified through the ratio of visceral adipose tissue (VAT) to subcutaneous adipose tissue (SAT) area (V/S ratio), may be associated wit...
Abstract 4368742: Long-term Impact of Aficamten on Patient-Reported Outcome Measures in Obstructive Hypertrophic Cardiomyopathy: Results From FOREST-HCM
Introduction: Treatment with aficamten in patients with obstructive HCM (oHCM) led to significant improvements in patient-reported outcomes (PROs) over 24 weeks in the pivotal SEQU...
Abstract 4373099: Gender Disparities in ECMO Utilization and Outcomes in Cardiogenic Shock: Insights from the Nationwide Inpatient Sample
Background: Despite advances in extracorporeal membrane oxygenation (ECMO) for cardiogenic shock (CS), little is known about gender-based differences in its utilization and clinica...
Abstract Sat903: Assessing Content Validity of EQ-5D-5L in Out-of-Hospital Cardiac Arrest Survivors: Cognitive Interviewing and Comparative Concept Mapping with HUI3 and SF-36
Background: The HUI3, SF-36, and EQ-5D-5L are generic instruments recommended for assessing out-of-hospital cardiac arrest (OHCA) survivors’ health-related quality of life (HRQoL)....