Circulation
Articles in this Issue
Abstract Sat1303: Factors Associated With Police Officers’ Willingness to Be Dispatched for CPR and AED Use: A Cross-Sectional Study in New Taipei City
Background: Out-of-hospital cardiac arrests (OHCAs) are a major public health concern worldwide. Early cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED...
Abstract 4371488: Impact of Iron Supplementation on Functional Capacity in Adults with Pulmonary Hypertension: A Systematic Review and Meta-Analysis
Background: Iron deficiency is a common comorbidity in patients with pulmonary hypertension (PH), affecting approximately 43–60% of this population. Iron plays a crucial role in ox...
Abstract 4363268: Scar formation and recovery from myocardial infarction can be modulated by targeting ADAM17 in fibroblasts vs. myofibroblasts
Background: Myocardial infarction (MI) triggers a complex remodeling process. Disintegrin and metalloproteinase-17 (ADAM17) is a membrane-bound proteinase with a broad range of sub...
Abstract 4357021: One-Year Outcomes of Mavacamten Versus Septal Myectomy in Hypertrophic Cardiomyopathy: A Propensity-Matched Retrospective Cohort Analysis
Background: Septal myectomy is the traditional standard for obstructive hypertrophic cardiomyopathy (HCM), yet mavacamten, a selective cardiac myosin inhibitor, has emerged as a no...
Abstract 4365022: Identification of a Novel Genetic Mutation in Hypertrophic Cardiomyopathy
Background: Mutations in various genes encoding sarcomeric proteins account for 50–60% of familial hypertrophic cardiomyopathy (HCM) cases. However, the molecular pathogenesis unde...
Abstract 4368683: Investigating the Peculiar Trends in Mortality due to Heart Failure and Pulmonary Edema; A Retrospective Study During 1999-2023
Background: Heart failure (HF) is a rapidly growing public health issue. Although the incidence of HF has stabilized globally, its prevalence continues to increase due to the agein...
Abstract 4368991: Prognostic Implications of Abnormal Right Ventricular-Pulmonary Artery Coupling Assessed by Three-dimensional Echocardiography in Heart Failure with Preserved Ejection Fraction
Background: In advanced stages of heart failure with preserved ejection fraction (HFpEF), right ventricular (RV) function declines, leading to abnormal RV-pulmonary artery (PA) cou...
Abstract 4365646: Paradoxical Stroke Via Persistent Levoatriocardinal Vein: A Case Report.
An 80-year-old male with a history of Parkinson's disease, dementia, and prostate cancer presented to the hospital with new onset right-sided weakness and aphasia. Emergency CT angiogram of the head a...
Abstract 4367939: Performance of General Adult Congenital Heart Disease (ACHD) Risk Calculators for Predicting Arrhythmic Substrate and Clinical Arrhythmias in Repaired Tetralogy of Fallot (rTOF)
Introduction: Patients with rTOF are at elevated risk of ventricular tachycardia (VT) and sudden cardiac death (SCD), primarily due to slowly conducting anatomic isthmuses (SCAI) f...
Abstract 4368740: Recurrent Purulent Pericardial Effusion and Cardiogenic Shock from Hypervirulent Klebsiella pneumoniae: A Case of Hepatopericardial Fistula
Case Presentation: A 55-year-old previously healthy woman presented to hospital with abdominal pain, fever, and dyspnea. She was hypotensive (SBP 70mmHg), acidotic (lactate >16...
Abstract 4369227: Outcomes of Myocardial Recovery in Pediatric Patients Supported with Ventricular Assist Devices: A Multi-Center Analysis of the UNOS Registry
Background: Myocardial recovery on durable left ventricular assist device (LVAD) support is a rare but important and understudied outcome. The incidence and outcomes of LVAD explan...
Abstract 4366656: An Ensemble AI-ECG Model for Detecting a Composite of Structural Heart Disease Had Higher Test-Retest Reliability than Disease-specific Tools Across Diverse Clinical Settings
Background: The scientific literature on artificial intelligence-enabled electrocardiography (AI-ECG) has defined a robust performance of AI models in detecting and predicting seve...
Abstract 4373090: COMPARISON OF CARDIOTOXIC EFFECTS BETWEEN AIs AEROMATASE INHIBITORS) AND SERMs (SELECTIVE ESTROGEN RECEPTOR INHIBITORS): A PHARMACOVIGILANCE ANALYSIS
Introduction: Cardiovascular (CV) diseases are a major cause of morbidity and mortality in breast cancer survivors. Side effects of antineoplastic agents used in treating breast ca...
Abstract 4366976: Permethrin, a common pyrethroid pesticide, promotes atherosclerotic plaque formation in ApoE null mice
Synthetic pyrethroids, such as permethrin, are commonly used insecticides in crop agriculture, clothing items such as camping and military uniforms, and for treating insect infestations in people and...
Abstract 4371237: Imaging Sympathetic Stress in Peripheral Artery Disease: Insights from Preclinical Models
Background: Peripheral artery disease (PAD) portends significant morbidity (immobility, limb amputation, life-threatening infections, etc) and an up to 10-fold greater mortality, y...
Abstract 4370991: ANCA-Negative Eosinophilic Myocarditis Masquerading as STEMI: A Case of Fulminant Cardiogenic Shock
Description of case: A 79-year-old man with hypertension, diabetes, and mild asthma presented after three days of weakness, abdominal discomfort, and dyspnea without chest pain. In...
Abstract 4366751: Long-Term Risk of Major Adverse Cardiovascular Events in Hematologic Malignancy Patients Treated with CAR-T Therapy: A TriNetX Propensity-Matched Cohort Analysis
Background: Chimeric antigen receptor T-cell (CAR-T) therapy is an innovative treatment for hematologic malignancies. However, its long-term cardiovascular safety profile remains u...
Abstract 4371452: Viscous Soluble Fiber Supplement Improves Glycemic Control but not Novel Cardiometabolic Markers in Type 2 Diabetes; A Randomized Control Trial
Introduction: Diabetes affected 529 million people globally by 2021, largely due to rising obesity contributing to Type 2 diabetes (DM2). In the U.S., it is the seventh leading cau...
Abstract Sat1208: Decoding Code Blue: An Analysis of Early Warning Scores, Diurnal Variation, and Potassium Prior to In-Hospital Cardiac Arrest
Background: Identifying patients at high risk for in-hospital cardiac arrest (IHCA) is critical for improving survival. While early warning scores (MEWS), metabolic derangements li...
Abstract 4364262: Independent Associations of Mitral Valve Prolapse Volume and LV Remodeling with Ventricular Ectopic Burden: A CMR Study
Background: Qualitative phenotypic features of arrhythmogenic mitral valve prolapse (MVP) have been described. We sought to determine the association of prolapse volume (PV) and le...
Abstract 4373057: Tethered Patient-Clinician Education to Improve Awareness and Treatment of Hypertrophic Cardiomyopathy (HCM): A Social Media–Driven Approach
Background: Despite advances in the diagnosis and treatment of hypertrophic cardiomyopathy (HCM), many patients feel disconnected from their clinicians and dissatisfied with their...
Abstract 4372695: HNRNPA1 Preserves PPP1R1B-lncRNA Binding with Polycomb Repressive Complex 2 during myogenic differentiation
Background: hnRNPA1 is an important member of the heterogeneous nuclear ribonucleoproteins (hnRNP) family, serves multiple functions. PPP1R1B-lncRNA...
Abstract 4358258: Physical Activity Preserves Exercise Capacity Over Two Years Of Breast Cancer Treatment (WF-97415)
Introduction: Women treated for breast cancer (BC) often experience declines in exercise capacity and cardiac function which increases their heart failure risk. Physical activity (...
Abstract 4373279: Multimodality Imaging–Based Phenotyping and Risk Stratification in Apical Hypertrophic Cardiomyopathy: Prognostic Implications of Right Ventricular Involvement
Background: Apical hypertrophic cardiomyopathy (HCM) exhibits substantial heterogeneity in morphology and function. Purpos...
Abstract 4371178: Exploring the Obesity Paradox: Impact of Obesity on Mortality and Inflammatory Markers in Acute Pulmonary Embolism
Background: Pulmonary embolism (PE) is a leading cause of cardiovascular morbidity and mortality. Obesity is a well-established risk factor for PE, yet the relationship between obe...