Angewandte Chemie International Edition
Articles in this Issue
Harnessing Molecular Recognition for Small‐Molecule‐Mediated Reversible Photochemical Control Over mRNA Translation
Abstract Chemical probes that control the function of complex RNA molecules offer unique opportunities to interrogate biological systems. In this study, we demon...
Optical Probes for Cellular Imaging of G‐quadruplexes: Beyond Fluorescence Intensity Probes
Abstract The study of G‐quadruplex (G4) structures that form in DNA and RNA is a rapidly growing field, which has evolved from in vitro studies of isolated G4 sequences to genome‐wid...
Online Coupling High‐Temperature Electrolysis with Carbonylation Reactions: A Powerful Method for Continuous Carbon Dioxide Utilization
Abstract Despite being widely available, the broad utilization of CO 2 for chemical production remains in its infancy. Th...
Construction of Multistep Charge Transfer Pathways in Bi <sup>0</sup> @Bi <sup>3+</sup> ‐KNbO <sub>3</sub> for Significantly Accelerated Photoconversion of Waste Plastics
Abstract Photoconversion of waste plastics into valuable CO and CH 3 COOH represents a ground‐breaking strategy for addre...
Enantio‐ and Diastereoselective Synthesis and Spiral‐Stair‐Like Single Helix Assembly of Figure‐Eight Cyclophenylenes
Abstract Helix assemblies of chiral molecules can transfer microscopic unimolecular chirality to macroscopic supramolecular chirality, enhancing various chiral properties. In additio...
Rapid Access to Conjugated <i>Z</i> , <i>Z</i> , <i>Z</i> ‐Trienes
Abstract Intercepting reactions have recently emerged as an innovative approach in organic synthesis, allowing chemists to harness reactive intermediates to acce...
Cross‐Linking Profiling of Molecular Glue Degrader‐Induced E3 Ligase Interactome to Expand Target Space
Abstract Molecular glue (MG) degraders, small molecules with significant therapeutic potential for targeting undruggable proteins, are emerging as new modality in drug discovery. Pro...
Molecular Stiffening by Macrocycle Clustering
Abstract Allosteric stiffening of a portion of a protein surface is a strategy used in nature to regulate protein oligomerization and provide crucial functions f...
Rapid Water Permeation by Aramid Foldamer Nanochannels With Hydrophobic Interiors
Abstract Aquaporins are natural proteins that rapidly transport water across cell membranes, maintaining homeostasis, whilst strictly excluding salt. This has in...
Improving Internal Exciton Confinement for Efficient CdZnSeS‐Based Blue Quantum Dot Light‐Emitting Diodes
Abstract Quantum‐dot light‐emitting diodes (QLEDs) are thought to be the base for next‐generation display technology. However, the performance of blue‐emitting QLEDs still falls behi...
Cobaloxime‐Based Metalloradical Catalysis: A Versatile Strategy for the Synthesis of Cyclopropenes and Oxazoles
Abstract Metalloradical catalysis (MRC), predominantly exemplified by metalloporphyrin complexes, has emerged as a promising strategy for regulating radical reactions and broadening...
Constructing Mechanical–Chemical Stability via Multiphase Riveting and Interface Optimization Toward Layer‐structured Oxide Cathode Material
Abstract Manganese‐based layer‐structured oxide materials are considered as one of the most competitive cathode materials for sodium‐ion batteries due to their l...
Compacting Molecular Stacking and Inhibiting Self‐Aggregation in Fullerene Transporting Layer for Efficient and Stable Perovskite Solar Cells
Abstract The underdevelopment of electron transport layer (ETL) materials remains a critical bottleneck limiting the overall photovoltaic performance of inverted...
Charge‐Transport Divergence in Ultrastable Heterometal‐Oxo Clusters Exerting Significant Effect on Photoreactivity
Abstract The transfer path of photogenerated charges greatly affects the final photocatalytic performance, but this important fact has not been clearly demonstra...
Spiro Units Embedded in the B/N Center for Constructing Highly Efficient Multiple Resonance TADF Emitters
Abstract Departing from conventional molecular design strategies that rely on spiro units merely as peripheral components (side chains, terminal groups, or linkage units), we fully o...
Cooperative Redox Reactions Encoded by Two Gene Clusters Enable Intermolecular Cycloaddition Cascade for the Formation of Meroaspochalasins
Abstract Meroaspochalasins (mAPOs) are a group of intricate heteromers comprising two distinct subunits, dienophile aspochalasin, and diene isobenzofuran, of whi...
Li <sub>21</sub> Ge <sub>8</sub> P <sub>3</sub> S <sub>34</sub> : New Lithium Superionic Conductor with Unprecedented Structural Type
Abstract Lithium superionic conductors are pivotal for enabling all‐solid‐state batteries, which aim to replace liquid electrolytes and enhance safety. Herein, w...
B ← N Lewis Pair Fusion of <i>N</i> , <i>N</i> ‐Diaryldihydrophenazines: Effect on Structural, Electronic, and Emissive Properties
Abstract Doping of polycyclic aromatic hydrocarbons (PAHs) with boron and/or nitrogen is emerging as a powerful tool to tailor the electronic structure and photo...
Highly Efficient Acceptors with a Nonaromatic Thianthrene Central Core for Organic Photovoltaics
Abstract Despite the great role in determining molecular packings and organic photovoltaic outcomes, very rare candidates could be employed as central cores in c...
Anode Engineering with pH‐Neutral Conjugated Polyelectrolyte Enabling Over 19% Efficiency in Organic Solar Cells
Abstract The lack of effective hole‐transporting layers (HTLs) materials has become a significant bottleneck in the advancement of organic solar cells (OSCs). Particularly, to obtain...
High‐Entropy Deep Eutectic Solvent Achieves Ultra‐Low Polarization Zinc Anode Chemistry
Abstract Deep eutectic solvents (DESs), a new class of green solvents, have emerged as promising candidates for electrolytes due to their exceptional electrochemical stability. Howev...
One‐Component Ionizable Amphiphilic Janus Dendrimers for Targeted mRNA Delivery
Abstract mRNA nanomedicine represents a new generation of therapeutics. However, how to deliver mRNA to the desired organs and cells effectively remains challenging. Common mRNA deli...
Modular Synthesis of Dendritic Oligo‐Glycerol Cationic Surfactants for Enhanced Antibacterial Efficacy
Abstract Bacterial infections and antibiotic resistance present an ever‐increasing threat to human health worldwide, and medicine urgently needs new alternatives for the successful t...
Imaging Heterogeneous Patterns of Aminopeptidase N Activity in Hierarchical Tissue Structures Through High‐Resolution Whole‐Organ 3D Mapping
Abstract Enzymes play a crucial role in regulating physiological functions, and abnormal enzyme activity is associated with various pathological conditions. Prec...
Hydrophobicity‐Controlled Self‐Assembly of Supramolecular Peptide Nanotubes in Water
Abstract Polymer‐conjugated peptides are attractive building blocks for the construction of new nanomaterials. However, the ability to control the self‐assembly of these materials re...