Angewandte Chemie International Edition
Articles in this Issue
Regulating Solvating Configuration to Achieve Long‐Cycle‐Life in Sodium‐SPAN Batteries
ABSTRACT Room‐temperature sodium–sulfur polyacrylonitrile (SPAN) batteries are regarded as promising energy storage technology due to their high energy density, low cost, and high sa...
Backbone‐Constrained Tripeptides Enable Sequence Control of Solid‐State Dynamics
ABSTRACT Understanding how peptide sequence relates to supramolecular dynamics and consequent solid‐state material properties remains a central challenge for rat...
Breaking Activity‐Stability Trade‐Off by Switching Reaction Pathway for Efficient Electrosynthesis of Glycerate at Industrial‐Scale Current Density
ABSTRACT The selective electrooxidation of biomass represents a sustainable solution for the synthesis of high‐valued chemicals, yet it remains challenging to ba...
Reticular Design of Hydrogen‐Bonded Organic Frameworks (HOFs): From Structure Tuning to Function Customization
ABSTRACT Hydrogen‐bonded organic frameworks (HOFs) have emerged as a distinctive class of porous crystalline materials assembled through directional yet reversible H‐bonds. Their mil...
Mechanically Planar Chiral Molecules by a SuFEx‐Auxiliary Approach
ABSTRACT Mechanical chirality, an emerging paradigm in stereochemistry, arises uniquely from the formation of a mechanical bond between achiral and oriented molecular subcomponents,...
N‐Rich Tris(triazole)‐Based 2D Conjugated Metal‐Organic Framework for High Performance Aqueous Dual‐Ion Batteries
ABSTRACT Two‐dimensional conjugated metal‐organic frameworks (2D c ‐MOFs) have emerged as promising host materials of iod...
Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α
ABSTRACT Protein kinases represent major pharmaceutical targets, but the development of selective modulators remains challenging. In search of allosteric sites in the serine/threonin...
Harnessing Methyltransferase‐Guided Targeting for Sequence‐Specific Proximity Labeling of DNA
ABSTRACT Methyltransferase (MTase)‐based DNA labeling has become a powerful strategy for genomic and epigenetic analysis because of its unique ability to recogni...
Self‐Sustaining Dynamic Alkaline Microenvironment‐Mediated Efficient Nitrate Electroreduction to Ammonia on MnFeO <sub>x</sub> in Neutral Electrolyte
ABSTRACT Electrocatalytic nitrate reduction (NO 3 RR) that utilizing renewable electricity to convert nitrate pollutants...
Single‐Atom La Promoter Breaks the Activity–Stability Trade‐Off on Al <sub>2</sub> O <sub>3</sub> ‐Supported Pt Catalysts for Propane Dehydrogenation
ABSTRACT Achieving acceptable propane conversion in the endothermic propane dehydrogenation (PDH) reaction demands high temperatures, which exacerbate the activi...
High‐Performance Ultra‐Narrowband Blue Electroluminescence via Intramolecular Noncovalent Interaction‐Enhanced Multiple Resonance Emitters
ABSTRACT The development of high‐performance blue organic light‐emitting diodes (OLEDs) is impeded by the scarcity of molecular scaffolds for ultranarrow multipl...
Built‐In Electric Field Modulates Phase Transition and Suppresses Voltage Hysteresis in Mn‐Based Phosphates Cathode for Sodium–Ion Batteries
ABSTRACT The voltage hysteresis and sluggish kinetics of Mn‐based mixed phosphate cathode significantly hinder their development and application. Herein, this wo...
Component‐Programmed Self‐Assembly for Topological Transformation: From a 2D Network to a Discrete Star of David
ABSTRACT Controllable modifications on dimensionalities and topologies of supramolecules are crucial for tuning their properties. Here, we report a robust compon...
<i>S</i> ‐Methyl Thioester Formation Uncovers Early Biosynthetic Steps of Yatakemycin
ABSTRACT Sulfur‐containing natural products are widely distributed in nature. Yatakemycin (YTM) is a complex antitumor and antifungal antibiotic featuring a typi...
Viologen Covalent Organic Frameworks Integrating Synergistic Singlet and Triplet Excitation for Efficient Photosynthesis of Benzazole Pharmaceuticals
ABSTRACT Viologen and its derivatives serve as an ideal platform for constructing radical‐type photocatalysts, but their reductive nature often causes stacking‐i...
De Novo Synthesis of Covalent Organic Frameworks: A Principle for Topology Selection and Profound <i>π</i> Electronic Effects
ABSTRACT Covalent organic frameworks are a class of crystalline porous polymers with well‐defined skeletons and ordered pores, making them attractive for structural design and synthe...
A Dual‐Key Gated Nuclear‐DNA‐Targeted Photogenerator for Amplified Photodynamic Immunotherapy of Breast Cancer
ABSTRACT Developing therapeutic agents that are capable of directly damaging nuclear DNA is critical for curing metastatic breast cancer. Herein, an enzyme‐media...
Photomediated Controlled Radical Homopolymerization of Sulfonated α‐Olefins and Vinyl Ethers with Propagating Sulfonyl Radicals
ABSTRACT Herein, we present the photomediated controlled radical homopolymerization of sulfonyl‐functionalized α‐olefin and vinyl ether monomers, yielding sequence‐controlled polysul...
Flower‐Shaped Supramolecular Polymer Enabling Biofilm Eradication, Improved Foliar Affinity, and Bacterial Disease Management
ABSTRACT The management of bacterial plant diseases is impeded by biofilm fortifications and the poor foliar affinity of conventional antimicrobials. Supramolecu...
Constructing High‐Power N‐Type Thermocells via Fluoride‐Mediated Imidazole–Iodine Coordination
ABSTRACT I − /I 3 − ‐based thermocells show great potential f...
Chiral Supramolecular Hydrogen Bonding Networks for Enantio‐Selective Catalysis Against Neuroinflammation
ABSTRACT Non‐covalent interactions are critical for regulating protein stability, reshaping catalytic active sites, and facilitating enzymatic reactions. Introducing these interactio...
T‐Shaped Stannyliumylidene Ion: Synthesis, Reactivity, and Redox Catalysis
ABSTRACT We report the synthesis and characterization of a T‐shaped, 8‐electron stannyliumylidene ion bearing a rigid acridane‐based pincer ligand. This cationic...
Reconfiguring Band‐Edge States in 2D Metal Halide Perovskites via Electron‐Donating and ‐Withdrawing Organic Cations
ABSTRACT Hybrid metal halide perovskites consist of the organic cation (A‐site) and inorganic skeleton (B‐site metal cation and X‐site halide anion). Traditionally, the electronic st...
Microbial Electrosynthetic Biohybrid System to Synergistically Supply Electrons and CO <sub>2</sub> to <i>Rhodopseudomonas palustris</i> for Lycopene Production
ABSTRACT Microbial electrosynthesis (MES) systems aim to use electroactive microorganisms (EAMs) to achieve electricity‐driven CO 2...
Kinetically Stereocontrolled <i>Gem</i> ‐Fluoro(chloro)‐Olefination of Carbonyls by an Unprecedented Sulfoximine: Programmable Construction of Challenging Persubstituted Alkenyl Fluorides
ABSTRACT Persubstituted alkenyl fluorides represent pivotal motifs in drug discovery, agrochemical development, and biological science. The (...