Circulation
Articles in this Issue
Abstract 4370390: Diet-Induced AMPK Activation Protects Against Cardiac Electrophysiological Dysfunction and Arrhythmias in Early Metabolic Stress
Background: Sudden cardiac death (SCD) is a major complication of diet-induced obesity. Whether early metabolic stress from nutrient overload per se, prior to overt obesity or rela...
Abstract 4341437: Anti-Arrhythmic drugs versus Catheter Ablation Prognostic value in the patients with Diastolic Heart Failure and Atrial Fibrillation: a Systematic Review and Meta-analysis of 38,237 Patients
Background: There is no definite consensus on the best treatment option for atrial fibrillation (AF) in heart failure (HF) with preserved ejection fraction (HFpEF) population....
Abstract 4362373: Strain and Deep Learning-Derived Mitral Regurgitation Features Are Independently Associated With Rheumatic Heart Disease - an analysis from the GOAL Trial
Background: Rheumatic heart disease (RHD) affects over 50 million people globally. Identifying latent RHD in asymptomatic children by echocardiography (echo) enables early secondar...
Abstract 4372296: A Site-by-Site Comparison of CT Attenuation, Effective Atomic Numbers, and Electron Densities of Focal Pericoronary Adipose Tissue and Its Relationship to Adjacent Coronary Plaques on Contrast Enhanced Spectral CT
Introduction: Inflammation in pericoronary adipose tissues (PCATs) may occur focally at adjacent plaque sites in the coronary arterial system as suggested by abnormal late-phase en...
Abstract 4371400: Disparities in Healthcare Access and Treatment Outcomes for Patients with Chronic Limb-Threatening Ischemia
Background: Chronic limb-threatening ischemia (CLTI) is clinically identified by the presence of a severe form of peripheral arterial disease that significantly affects the patient...
Abstract 4368589: Impact of Single-Pill Combination Therapy on Nocturnal Blood Pressure Dipping in Indian Patients: A Subanalysis from the TOPSPIN Trial
Background: Non-dipping and reverse-dipping of nocturnal blood pressure (BP) are associated with increased cardiovascular risk. Data on dipping status and its modulation by Single-...
Abstract 4363591: Geographic and Demographic Trends in Aortic Aneurysm and Dissection Mortality Among U.S. Adults Aged 65–75, 1999–2020
Background: Aortic aneurysm and dissection (AAD) are highly fatal in older adults. While AAD mortality has declined since 1999, reductions have been uneven across U.S. regions, sex...
Abstract 4369611: The Long Pause: What Gaps in Care Reveal about Congenital Heart Disease Outcomes
Introduction/Background: Lifelong continuity of care is essential for individuals with congenital heart disease (CHD). Despite guidelines recommending uninterrupted follow-up, gaps...
Abstract 4362335: Accelerated Pacing Reverses Ventricular Stiffening in a Rodent Model of Diastolic Dysfunction
Heart failure with preserved ejection fraction (HFpEF) has long been managed with pharmacologic heart rate reduction, in part to increase ventricular filling time. However, this approach overlooks the...
Abstract 4360862: Impact of Push Notifications on Physical Activity and Sodium Intake Amongst Patients with Hypertension: A Micro-Randomized Trial of a Just-In-Time Adaptive Intervention
Background: Achieving adequate blood pressure (BP) control is challenging for patients and clinicians given the episodic nature of clinical encounters, high patient volumes, and si...
Abstract 4358817: Circulating Metabolomic Signatures of Ambient Air pollution and Riks of Atrial Fibrillation Incidence: a Prospective Cohort Study
Background: Ambient air pollution has been linked to atrial fibrillation (AF), yet the underlying metabolic mechanisms remain poorly understood....
Abstract 4337531: Telehealth Experiences and Preferences Among Patients with Cardiovascular Disease Risk Factors
Introduction: The American Heart Association (AHA) Center for Telehealth aims to address gaps in the telehealth landscape by guiding telehealth integration into outpatient settings...
Abstract 4366948: Multi-View Deep Learning for Automated Quantification of Mitral Stenosis
Background: Accurate assessment of mitral stenosis (MS) severity is critical to guide timely clinical management. Current evaluation relies on expert interpretation of B-mode and D...
Abstract 4355008: Socioeconomic, Lifestyle, and Psychosocial Correlates of Racial and Ethnic Disparities in Hypertension Prevalence, Control and Incidence: The Multi-Ethnic Study of Atherosclerosis
Background: Hypertension (HTN) is a key driver of cardiovascular disease (CVD). Racial and ethnic disparities in HTN have been noted, yet the contributions of socioeconomic, lifest...
Abstract 4343216: Guideline-Directed Medical Therapy and Clinical Outcomes in African American Women with Congestive Heart Failure from Low- to Medium-Income Backgrounds at a Safety Net Hospital
Background: Heart failure among African American women represents a significant public health challenge. The high prevalence of comorbidities often necessitates selective implement...
Abstract 4370795: Demographic and Regional Trends in Cardiovascular Disease Mortality Among Individuals with AIDS in the United States: A Retrospective 22-Year Analysis
Background: Cardiovascular disease (CVD) is a significant risk factor among individuals with acquired immunodeficiency syndrome (AIDS), influenced by factors such as HIV-related in...
Abstract 4369351: Factors Associated with Poor Patient Outcomes in the First 24 Hours after Out of Hospital Cardiac Arrest
Introduction: Patients with return of circulation after an out of hospital cardiac arrest (OHCA) remain at high risk for in-hospital morbidity and mortality from multiorgan dysfunc...
Abstract 4363280: Comparison of One-Year Survival between Norwood and Hybrid Pathways for Hypoplastic Left Heart Syndrome Infants- A Multicenter Registry Data Analysis
Introduction: The choice of Stage 1 palliation (S1P) in patients with hypoplastic left heart syndrome/complex (HLHS/C) between Norwood Stage 1 (NS1) or Hybrid Stage 1(HS1) palliati...
Abstract Sat1304: A Predictive Score for In-Transit Cardiac Arrest in Trauma Patients: Development and Validation Using a National Registry
Introduction: In-Transit cardiac arrest in trauma patients, although infrequent, is a critical event with high mortality. Accurate prediction of this event at emergency medical ser...
Abstract 4351394: Severe Aortic Stenosis Due to Libman-Sacks Endocarditis as the First Manifestation of SLE in a Young Male
Background: Libman-Sacks endocarditis (LSE) is a rare, non-infective form of endocarditis, often associated with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (A...
Abstract 4367359: Understanding the association between patient empowerment level and patient-prioritized education topics in adult congenital patient population: A descriptive cross-sectional study
Background: Adults with congenital heart disease (CHD) face ongoing physical, emotional, and psychosocial challenges that impact long-term outcomes. Research is limited on how thei...
Abstract 4370897: Sydenham Chorea as the Presenting sign of Rheumatic Heart Disease in a 12 Year old
Introduction: Sydenham chorea (SC) is a form of acquired chorea of childhood and is linked to Acute Rheumatic Fever (ARF), which is an autoimmune response to infection with Group A...
Abstract 4364999: Clinical Features And Hemodynamic Response of Microaxial Flow Pump Treatment in Cardiogenic Shock With or Without Myocardial Infarction
Background: Recent DanGer-Shock trial demonstrated potential mortality benefit of microaxial flow pumps (mAFP) in select patients with acute myocardial infarction cardiogenic shock...
Abstract 4367017: Handgrip Strength, Obesity, and Outcomes in Heart Failure with Preserved Ejection Fraction
Background: Obesity is paradoxically associated with better outcomes in adults with heart failure with preserved ejection fraction (HFpEF). Handgrip strength is a simple validated...
Abstract Sat405: Do Neuroprognostic Studies in Comatose Cardiac Arrest Survivors Report Factors Contributing to Self-Fulfilling Prophecy Bias in Their Methodology? A Systematic Review
Background: Self-fulfilling prophecy bias (SFPB) occurs when a perceived prognosis guides treatment decisions, thereby modulating outcomes and potentially inflating the prediction...