Circulation
Articles in this Issue
Abstract Sun1203: Prehospital Transcutaneous Pacing: A Multicenter Retrospective Cohort Study of Sustained Electrical Capture Prevalence, Predictors, and Associated Outcomes
Introduction: Transcutaneous pacing (TCP) is used to treat bradycardia with hemodynamic compromise. A single-center study found that sustained electrical capture (SEC) was uncommon...
Abstract 4370639: Association between circulating ceramides and cardiac function among women receiving adjuvant chemotherapy for breast cancer.
Background: Cancer treatment is increasingly recognized as a contributor to elevated cardiovascular disease risk. Ceramides, small bioactive lipids, play a critical role in various...
Abstract 4368921: Artificial Intelligence Prediction of Atrial Fibrillation Using Pre-Cannulation Electrocardiograms in Patients Undergoing Veno-Venous Extracorporeal Membrane Oxygenation
Backround: Atrial fibrillation (AF) is a common complication following veno-venous extracorporeal membrane oxygenation (VV-ECMO), leading to further complications from anticoagulat...
Abstract 4342688: Comparison of Clinical Outcomes of DOACs versus Warfarin in patients with nonischemic HFrEF and HFpEF: A Retrospective Cohort Study
Background: The incidence, management, and outcomes of left ventricular (LV) thrombus in nonischemic cardiomyopathy (NICM) remain poorly defined....
Abstract 4367742: AAV-mediated Gene Delivery of PERM1 Prevents the Development of Heart Failure with Reduced Ejection Fraction in a Mouse Model of Pressure Overload
Introduction: Heart failure with reduced ejection fraction (HFrEF) affects over 3 million adults in the United States with high mortality. HFrEF is marked by impaired cardiomyocyte...
Abstract Sat102: Heterogeneous Treatment Effects of Laryngeal Tube Insertion versus Endotracheal Intubation on Return of Spontaneous Circulation following Out-of-Hospital Cardiac Arrest
Introduction: Previous work suggested a benefit of laryngeal tube (LT) insertion over endotracheal intubation (ETI) in adults with out-of-hospital cardiac arrest (OHCA). But, it re...
Abstract 4370190: Geographic and Demographic Disparities in NAFLD and Cardiovascular Mortality in the United States: Insights from the CDC WONDER Database
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition globally. Cardiovascular disease (CVD) is the leading cause of death in this popula...
Abstract 4368927: Fat Mass and Systolic Blood Pressure are Modifiable CV Risk Factors Associated with Adverse Myocardial Changes in Patients with Duchenne Muscular Dystrophy
Introduction/Background: Patients with Duchenne muscular dystrophy (DMD) typically develop pathologic changes in body composition (increased fat mass and decreased lean mass) as we...
Abstract 4347475: Dostarlimab-Induced Diabetic Ketoacidosis in a Non-Diabetic Patient with Acute Myocardial Infarction: A Case Report
Background: Diabetic ketoacidosis (DKA) is a life-threatening complication commonly associated with type 1 diabetes. However, it can also develop in patients without a known histor...
Abstract 4373422: Prediction of Pulmonary Arteriosclerosis and Elevated Pulmonary Arterial Systolic Pressure Using Effective Atomic Numbers and Electron Density of Focal Peri-Pulmonary Arterial Adipose Tissue on Spectral CT in Patients without Coronary Arterial, Myocardial, and Valvular Diseases
Introduction: Inflammation in pericoronary adipose tissue may occur focally at adjacent plaque sites in the coronary arterial system. Similarly, inflammation in peri-pulmonary arte...
Abstract 4366760: Sex-Based Differences in Short- and Long-Term Outcomes Following Aortic Dissection in Patients with Connective Tissue Disease
Background: Connective tissue disorders (CTDs), including Ehlers-Danlos syndrome (EDS) and Marfan syndrome (MS), are known risk factors for aortic dissection (AD). Sex-based dispar...
Abstract 4339966: Trends in Mortality of Hypertension and Cerebrovascular Diseases in the Adult Population: CDC Data Analysis (1999–2020)
Background: Hypertension causes about 70% of strokes worldwide and raises the risk of cerebral small vessel disease by 1.5 times, the major cause of stroke and vascular dementia. T...
Abstract 4364669: Systematic Review and Meta-Analysis on CardioMEMS for Enhanced Heart Failure Management: Examining Randomized Controlled Trials and Observational Studies
Introduction: Patients with severe or advanced heart failure symptoms are often hospitalized for acute decompensated heart failure despite being on guideline-directed medical thera...
Abstract 4358419: Lower Estimated Glucose Disposal Rate Predicts Higher Cardiovascular Risk and Mortality in Type 1 Diabetes: A Systematic Review and Meta-Analysis
Background: Cardiovascular disease remains the leading cause of morbidity and mortality among individuals with type 1 diabetes mellitus (T1DM). Insulin resistance, increasingly rec...
Abstract 4371686: Impact of Artificial Intelligence on Cardiovascular Disease Diagnosis, Risk Assessment, and Treatment: A Meta-Analysis of 45 Studies
Background: AI holds great potential in improving cardiovascular disease diagnosis, risk assessment, and treatment. However, its clinical utility requires thorough validation throu...
Abstract 4367916: Pioneering Pericarditis Management in Pregnancy
Background: Pericarditis is a rare obstetric complication. Severe pericardial disease may lead to tamponade physiology, jeopardizing both the mother and fetus. We report a case of...
Abstract 4366598: Comparative Performance of PCE, PREVENT, and CAC for MACE Prediction in Asymptomatic Patients
Introduction/Background: Current prediction models including the Pooled Cohort Equations (PCE) and the novel PREVENT score are used for assessing atherosclerotic cardiovascular dis...
Abstract 4366830: Symptoms of Bladder Incontinence Are Associated with Worse Functional Status and Quality of Life in Heart Failure with Preserved Ejection Fraction
Introduction: Heart failure with preserved ejection fraction (HFpEF) is a geriatric syndrome characterized by a high burden of frailty, sarcopenia, and physical dysfunction. Given...
Abstract 4367467: Fatal Bilateral Septic Embolic Stroke from Left Atrial Roof Endocarditis Following Atrial Fibrillation and Flutter Ablation
A 67-year-old male with prior CABG (2022), atrial fibrillation, and dual-chamber pacemaker (implanted November 2024) underwent radiofrequency ablation for atrial fibrillation with additional cavotricu...
Abstract 4357563: Genetic Testing Yield and Associations with Disease Phenotype for Thoracic, Coronary, Abdominal, and Cervical Aneurysms and Dissections
Background: Clinical genetic testing is an increasingly important component of cardiovascular care and has direct impacts on the medical and surgical management of patients and rel...
Abstract 4358448: R-propranolol Attenuates Interleukin-18 Mediated Sickle Cell Cardiomyopathy: A Novel Adrenergic-independent Mechanism Involving Lipid Synthesis.
Background/Hypothesis: We previously reported that interleukin-18 (IL-18) mediates sickle cell cardiomyopathy (SCC), characterized by diastolic dysfunction, heart failure, and vent...
Abstract Sun1102: Can Post Resuscitation Clinical Debriefing impact patient outcomes
Background: Cardiac arrest (CA) remains a leading cause of in-hospital mortality, with survival-to-discharge rates ranging from 10% to 32%. Although timely, high-quality cardiopulm...
Abstract 4342979: Early vs Delayed Ablation for New-Onset Atrial Fibrillation
Background: Recent updated guidelines recognize catheter ablation as a first-line therapy for symptomatic atrial fibrillation (AF). The optimal timing of catheter ablation followin...
Abstract 4353481: Worsening diet quality and low behavioral health scores among US adults with Preclinical Heart Failure: National Health and Nutrition Examination Survey 2007-2018
Background: With heart failure (HF) prevalence rising, targeting its preclinical stages is key to prevention and reduction of morbidity and mortality. The American Heart Associatio...
Abstract 4367089: Decade of disparity: Racial Representation in Clinical Trials in Cardiovascular Disease in the United States and United Kingdom (2015–2025)
Background: Awareness of health disparity have grown, however certain demographic groups particularly racial minorities, continue to be underrepresented. This limits the generaliza...