Circulation
Articles in this Issue
Abstract 4371709: Cardiovascular Interventions and Mortality in Recurrent Infective Endocarditis and Substance Use Disorder: The Paradox of Procedure
Background: Infective endocarditis (IE) recurrence is common among patients with substance use disorder (SUD) and is often met with repeated cardiac interventions due to their youn...
Abstract 4371381: Outcomes of Ventricular Tachycardia Ablation in Cardiac Laminopathy: An Updated Systematic Review and Single-arm Meta-analysis.
Background: Ventricular tachycardia (VT) is a potentially life-threatening arrhythmia frequently observed in structural heart diseases, including cardiac laminopathy, a genetic car...
Abstract 4363332: Comparative Efficacy of Cangrelor in Patients Undergoing PCI in the setting of Cardiogenic Shock or Cardiac Arrest: Insights from Blue Cross and Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry
Background: Cangrelor has more rapid platelet inhibition compared to oral anti-platelet agents. The favorable pharmocokinetics and pharmacodynamics of cangrelor could be advantageo...
Abstract 4368526: Libman-Sacks Endocarditis as the Initial Manifestation of Systemic Lupus Erythematosus in a HIV-Positive Patient: A Rare Case of Multi-Organ Embolic Events
Backround: Libman-Sacks endocarditis (LSE), a form of nonbacterial thrombotic endocarditis (NBTE), is commonly associated with systemic lupus erythematosus (SLE), antiphospholipid...
Abstract 4347326: Catheter Ablation Versus Antiarrhythmic Drug Therapy for Ventricular Tachycardia in Structural Heart Disease: A Meta-Analysis of Randomized Controlled Trials
Background: Ventricular tachycardia (VT) is a life-threatening arrhythmia often seen in patients with structural heart disease. While antiarrhythmic drugs (AADs) have long been sta...
Abstract 4369839: Thromboembolic Events and Bleeding Risk with Antithrombotic Strategies for Peri-Device Leak After Percutaneous Left Atrial Appendage Occlusion
Background: The 2023 American Heart Association guidelines recommend left atrial appendage occlusion (LAAO) for nonvalvular atrial fibrillation patients with oral anticoagulants (O...
Abstract 4365037: Social Factors Associated with Pre-Pregnancy Care Utilization
Background: The American Heart Association recognizes the pre-pregnancy period as a window to optimize cardiovascular health and mitigate the risk of adverse pregnancy outcomes, pa...
Abstract 4348795: Elevated LDL-C and Fasting Plasma Glucose Predict Benefit from Invasive Strategy in Chronic Coronary Disease: A Causal Forest Analysis of the ISCHEMIA Trial
The ISCHEMIA trial showed no significant difference in the rate of primary outcome events between patients with chronic coronary artery disease who used invasive strategies (INV) versus conservative s...
Abstract 4366634: The Relationship between Reported Fish Oil Supplement Use and Health Outcomes in the UK Biobank
Introduction: Recent headlines citing UK Biobank (UKBB) data (Chen et al. BMJ-Med 2024;3:e000451) reported that fish oil supplement (FOS) use increased risk for atrial fibrillation...
Abstract 4362696: Temporal Trends and Machine Learning Prediction for Chronic Kidney Disease Due to Hypertension in Young Adults from 1990 to 2021: An Analysis of the Global Burden of Disease Study 2021
Background: Young adults aged 25 to 49 years, who are at the peak of their professional and familial responsibilities, face significant health and societal productivity challenges...
Abstract 4366893: Effects of Concordance and Discordance of Coronary Calcium Density and Volume on Major Adverse Cardiac Event Outcomes
Introduction: Coronary artery calcium (CAC), quantified by the Agatston score on cardiac CT, is a well-established measure of atherosclerotic burden. While the Agatston score combi...
Abstract 4370792: Impact of Photon counting CT on the Diagnostic Performance of CTA in Elderly Population
Background: Coronary computed tomography angiography (CTA) is a well-established noninvasive tool for diagnosing coronary artery disease (CAD). However, its accuracy may be limited...
Abstract 4342658: Sub-optimal guideline-concordant anticoagulation after atrial fibrillation ablation
Introduction: Catheter ablation (CA) is a treatment strategy for patients with atrial fibrillation (AF). The 2023 ACC/AHA/ACCP/HRS guidelines recommend oral anticoagulant (OAC) the...
Abstract 4356757: Double Trouble: Impact of Viral Pneumonia on Mortality and Clinical Outcomes in Patients Hospitalized with Pulmonary Embolism: A Nationwide Analysis (2016 – 2021)
Background: Pulmonary Embolism (PE) is a potentially life-threatening condition that warrants careful consideration of its risk factors and associated comorbidities. Viral pneumoni...
Abstract 4363828: Cardiologist Attitude to Lipid Control in Patients with ASCVD without Major Cardiovascular Events: Insights from the 2024 ACS EuroPath Survey
Introduction: The perception and attitudes of physicians are important factors for the implementation of cardiovascular prevention and guidelines. Here we present data on patients...
Abstract 4361420: Systemic Mitochondrial Function in Young Adults with Perinatal HIV Exposure and Infection with Cardiac Inflammatory Biomarkers and Echocardiogram Parameters
Introduction: Children with perinatally-acquired HIV (PHIV) are now reaching adulthood due to improved antiretroviral treatment (ART); however, the cardiac comorbidities associated...
Abstract 4371994: Impact of Atrial Fibrillation on 1-Year Clinical Outcomes in Hypertrophic Cardiomyopathy: A Multicenter Observational Analysis
Background: Atrial fibrillation (AF) is a common comorbidity in hypertrophic cardiomyopathy (HCM), yet its incremental impact on clinical outcomes remains incompletely defined. We...
Abstract 4363699: The Effect and Safety of Ketogenic Diets on LDL-C and other metabolic parameters compared with non-ketogenic diets among Adults with BMI Greater than 25 with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Objective: To determine the effects of a ketogenic diet on LDL-C levels and other metabolic parameters and adverse events in adults with a BMI greater than 25 and type 2 diabetes m...
Abstract 4371380: Prospective Comparison of 3D Rotational Angiography and Computed Tomographic Angiography in Carotid Artery Stenosis
Evaluation of carotid artery stenosis (CAS) is an essential step of preprocedural planning. Computed tomography angiography (CTA) is currently widely utilized, however three-dimensional rotational ang...
Abstract 4373576: Multi-Ancestry GWAS of AI-Derived Echocardiographic Traits
Genome-wide association studies (GWAS) of cardiac structure and function have historically relied on a limited set of manually derived echocardiographic measurements, and more recently deep-learning d...
Abstract 4364175: Human PAH Hepatopathy Is Characterized by Metabolic and Inflammatory Alterations That Are Distinct from Other Human Hepatopathies
Background: Right ventricular failure (RVF) is the strongest risk factor for mortality in pulmonary arterial hypertension (PAH). RVF is deadly because it leads to multi-organ dysfu...
Abstract 4373601: QTc interval monitoring with a smartphone ECG in patients with cancer
Background: Patients undergoing cancer therapies with QTc prolonging effects are required to make frequent clinic visits to obtain 12-lead ECGs for QTc monitoring. This practice is...
Abstract 4364124: Reducing Medicare 30-day heart failure readmissions and saving dollars with an aggressive “ <i>4 Weeks 4 Meds</i> ” heart failure clinic
Background: Medicare heart failure readmissions are costly. The Hospital Readmissions Reduction Program (HRRP) penalizes hospitals for high rates of Medicare 30-day heart failure (...
Abstract 4358782: Redefining Cardiotoxicity Surveillance in Targeted Immunotherapy: Cytokine Release Syndrome as a High-Yield Trigger for Detecting Cancer Therapy-Related Cardiac Dysfunction After CAR-T Therapy
Introduction: Chimeric antigen receptor T-cell (CAR-T) therapy offers durable remissions in hematologic malignancies but carries a substantial risk of cancer therapy–related cardia...
Abstract 4355053: Changes in Cardiopulmonary Exercise Performance Following Atrial Fibrillation Ablation
Background: Recent studies have shown that catheter ablation (CA) for atrial fibrillation (AF) was associated with significant hemodynamic improvements, improved exercise capacity,...