Circulation
Articles in this Issue
Abstract 4354030: Progressive Flap Thickening Mediated by Wall Shear Stress in Chronic Type B Aortic Dissection
Introduction: Type B Aortic Dissection (TBAD) is a lethal disease. The dissection flap demonstrates morphologic and biomechanical changes as the dissection transitions from the acu...
Abstract 4362365: Clinical characteristics and outcomes of infective endocarditis in patients with maintenance hemodialysis
Background: Patients undergoing maintenance hemodialysis (HD) are at increased risk of infective endocarditis (IE), but current data regarding their clinical profiles and outcomes...
Abstract 4372084: Robot-Assisted Mitral Valve Repair versus Conventional Sternotomy versus Minimally Invasive Procedure for Degenerative Mitral Regurgitation: A Systematic Review and Network Meta-Analysis of Intra-Hospital Mortality and Myocardial Infarction
Introduction: Degenerative mitral regurgitation (DMR) is a common valvular heart disease requiring surgical intervention. While conventional sternotomy (CS) has been the traditiona...
Abstract 4359561: Win Ratio Analysis of Low-Voltage Area Ablation in Persistent Atrial Fibrillation: a Sub-Analysis of the SUPPRESS-AF Study
Background: In patients with persistent atrial fibrillation (AF), low-voltage areas (LVAs) in the left atrium are considered potential arrhythmogenic substrates. While additional s...
Abstract 4370031: Targeting Asprosin For Treatment of Hypertension
Background: Hypertension is a leading risk factor for cardiovascular disease and is strongly associated with metabolic syndrome (MS), particularly obesity, through complex and mult...
Abstract Sun1401: The Perils of Standard Management of an Underrecognized Cause of Shock
Case Presentation: Case 1: An 83-year-old female without medical history developed cardiogenic shock due to anterior STEMI. Post-LAD stenting and IABP placement, her cardiac index...
Abstract 4364382: Trends and Demographical Differences in Anomalous Aortic Origin of a Coronary Artery-related Mortality in the United States, 1999-2023
Background: Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital anomaly affecting around 0.1-0.3% of the population and is a known cause of myocardial ischemi...
Abstract 4369193: Burden of Heart Failure in 4,573 Children and Adults with Fontan Physiology: Epidemiology and Outcomes from a Decade-Long Seven-State US-Based Surveillance Network
Introduction: The prevalence of heart failure (HF) among U.S. patients (pts) with Fontan physiology is poorly defined, with estimates generally derived from single centers. We leve...
Abstract 4365301: High Visceral-to-Subcutaneous Fat Ratio is Correlated with Increased Coronary Artery Disease Severity Based on Computed Tomography-derived SYNTAX Score Regardless of Physique Stratified by Lean Body Mass Index
Background: The lean body mass index (LBMI) is determined by dividing an individual’s lean body mass by the square of their height. It is closely linked to skeletal muscle mass and...
Abstract 4369612: Finerenone Reduces Loop Diuretic Requirement in Patients with Type 2 Diabetes and CKD: Participant-Level Pooled Analysis of FIDELIO-DKD and FIGARO-DKD
Background: The nsMRA finerenone, has been shown to reduce the risk of kidney disease progression and CV events in patients with T2D and CKD. Diuretics are widely used in the manag...
Abstract 4363592: Clinical and Demographic Characteristics of Critically Ill Acute Coronary Syndrome Hospitalizations With and Without Postprocedural Circulatory System Complications
Background: Postprocedural and postoperative circulatory system complications among patients with acute coronary syndrome (ACS) are associated with increased clinical severity, pro...
Abstract Sun602: Lower Survival After Out-of-Hospital Cardiac Arrest in Older Females: The Joint Effect of Age and Sex
Background: Sex-based differences in survival following out-of-hospital cardiac arrest (OHCA) have been widely studied, but the joint effect of age and sex remains unclear....
Abstract 4342599: Incidence and Predictors of Atrial Tachyarrhythmia in Fontan Patients from the Fontan Outcome Registry using CMR Examinations (FORCE)
Background: The Fontan procedure has significantly extended the lifespan of patients with single-ventricle congenital heart disease. Atrial tachyarrhythmias (AT) are known to be as...
Abstract 4366343: Persistent Focal Atrial Tachycardia In A Young Pregnant Woman: When Stability Isn’t Safe
A 23-year-old woman at 28 weeks of gestation with a childhood history of SVT managed with beta-blockers and no follow-up presented with sudden-onset palpitations, dyspnea, and fatigue....
Abstract 4371398: Glucagon Receptor Agonist Impact on Cardiac Amyloidosis. A Retrospective Propensity Matched Analysis
Introduction: Cardiac amyloidosis is a complex and progressive infiltrative cardiomyopathy associated with high morbidity and mortality. Recent studies have raised interest in the...
Abstract 4369781: Predictors of Mortality Among Elderly Patients Undergoing Redo Surgical Mitral Valve Replacement; a National Estimate in the United States
Introduction: Although redo surgical mitral valve replacement(redo-SMVR) is associated with a higher mortality risk compared to valve-in-valve transcatheter mitral valve replacemen...
Abstract 4370605: Early versus Late Initiation of Anticoagulation in Acute Ischemic Stroke With or Without Atrial Fibrillation: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis
Background: The optimal timing of anticoagulation following acute ischemic stroke remains debatable, particularly in patients with or without atrial fibrillation (AF), where balanc...
Abstract 4358402: Multifactorial Cardiogenic Shock: Integrating Percutaneous and Device-Based Strategies When Advanced Heart Replacement Therapies Are Contraindicated
Clinical Case: A 62-year-old male with a history of HTN, HLD, and AUD, presented with an inferior STEMI. Angiography revealed a 95% mid RCA cul...
Abstract 4362307: Automated Aortic Valve Motion Analysis from Echocardiography for Efficient Classification of Aortic Stenosis Severity
Background: Aortic stenosis (AS) severity assessment traditionally relies on Doppler echocardiography, which is time-consuming and may be inconclusive in a subset of patients. Effi...
Abstract Sat703: Challenging Convention Regarding Pediatric Non-Shockable Rhythms: Pulseless Electrical Activity and Asystole as Distinct Initial Rhythms
Background: Asystole and PEA occur as the initial rhythm in ~85% of pediatric IHCA yet are grouped together as “non-shockable” rhythms in resuscitation research and practice....
Abstract 4361027: Bempedoic acid monotherapy, LDL cholesterol and cardiovascular events: a secondary analysis of the CLEAR Outcomes trial
Background: Bempedoic acid lowers LDL-cholesterol (LDL-C) and reduces major adverse cardiovascular events (MACE) in statin-intolerant patients at high risk for, or with, establishe...
Abstract 4363024: Longitudinal Trends and Disparities in Hypertension and Hyperlipidemia Related Mortality in the United States from 2000 to 2020
Background: Hypertension (HTN) and Hyperlipidemia (HLD) are two modifiable, prevalent risk factors that synergistically contribute to cardiovascular and stroke morbidity and mortal...
Abstract 4356257: Neighborhood Level Social Disadvantage Indices and Cardiovascular Disease Prevalence in California
Introduction: Cardiovascular disease is the leading cause of death in California (CA) and social determinants of health accounts for some of the geographic variations in cardiovasc...
Abstract 4363052: In Vivo and Clinical Evidence of HDL Electronegativity in Atherogenicity
Background: High-density lipoprotein (HDL) is classically recognized for its atheroprotective functions, including facilitating reverse cholesterol transport and reducing vascular...
Abstract 4366909: Transcriptomic signature network discovery of type 2 diabetes-increased cardiovascular risk through single-cell transcriptomic analysis
Background/Objective: Type 2 diabetes (T2DM) remains a major risk factor for atherosclerotic cardiovascular disease (ASCVD) despite modern lipid, glycemic and hypertension control...