Circulation
Articles in this Issue
Abstract 4373293: Immune Checkpoint Inhibitor Thyroid Dysfunction is Associated with Increased Incidence of Coronary Artery Disease and Arrhythmia
Introduction: Immune checkpoint inhibitor (ICI) induced hypothyroidism is a common immune related adverse event during cancer immunotherapy, but the association with cardiovascular...
Abstract 4360240: Test-Retest Reliability of Resting-State Pulse Rate Variability in Young Adults
Background: Pulse rate variability (PRV), measured through photoplethysmography (PPG), can serve as an approximate measure of cardiac autonomic regulation. Despite its increasing a...
Abstract 4364855: Linking <i>In Vivo</i> Flap Motion to <i>Ex Vivo</i> Flap Thickness in Type B Aortic Dissection: Acute vs Chronic Insights
Introduction: Type B aortic dissection (TBAD) is a serious condition that may benefit from early endovascular repair. In the acute phase (aTBAD; <14 days onset), the high compli...
Abstract 4369002: Blood Pressure Variability and Implications for Trial Screening
Background: Blood pressure (BP) is a dynamic measure influenced by contextual and behavioral factors, with well-established evidence showing notable differences between office (OBP...
Abstract 4365946: Trends in Heart Failure and Vascular Disease Mortality Among U.S. Adults Aged 55 and Older, 1999–2019: A Retrospective Analysis
Background: Heart failure and vascular diseases remain leading causes of death in the United States. Although mortality declined in the early 2000s, recent years have raised concer...
Abstract 4363064: Late-Onset Donor-Derived Hypertrophic Cardiomyopathy Following Orthotopic Heart Transplant
Background: Heart transplantation (HT) complications include rejection and infection. Rarely, monogenic donor cardiomyopathies—especially hypertrophic cardiomyopathy (HCM)—can mani...
Abstract 4365587: Efficacy of finerenone in patients with heart failure and mildly reduced or preserved ejection fraction: A prespecified analysis of heart rate in the FINEARTS-HF trial
Background: The association between heart rate (HR) and clinical outcomes is well understood in patients with heart failure and reduced ejection fraction (HFrEF), but less clear in...
Abstract 4364006: Early Partial ECMO Flow Is Associated With Higher Survival in Patients With Cardiogenic Shock With Reduced and Preserved Systemic Pulse Pressure: An ELSO Registry Analysis
Introduction: In cardiogenic shock (CS) patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), emerging observational evidence suggests potential benef...
Abstract 4366899: Ischemic ECG Changes Among Patients With Post-PCI Myocardial Injury Are Not Associated With Increased Long-Term All-Cause Mortality
Introduction: Myocardial injury following elective percutaneous coronary intervention (PCI) is associated with reduced long-term survival. Ischemic changes on electrocardiogram (EC...
Abstract Sat1204: Agency Epinephrine Dosing Intervals and Patient Characteristics in Out-of-Hospital Cardiac Arrest: A National EMS Study
Background: The optimal timing of epinephrine dosing in out-of-hospital cardiac arrest (OHCA) remains uncertain, and practice patterns may vary across emergency medical services (E...
Abstract 4342582: Modifying the progression of heart failure with preserved ejection fraction (HFpEF) in pigs by a regular exercise regimen; Effects on LV function and structure
Background: HFpEF commonly arises from a persistent left ventricular (LV) pressure overload (LVPO) ultimately causing hypertrophy, and resistance to LV filling resulting in increas...
Abstract 4373041: Sotatercept-Enhanced Quadruple Therapy Reverses Hemodynamic Decline in Severe Systemic Lupus Erythematosus-Associated Pulmonary Arterial Hypertension
Background: Pulmonary arterial hypertension (PAH) is a rare but potentially fatal manifestation of systemic lupus erythematosus (SLE), occurring in a minority of patients and often...
Abstract 4363683: Unveiling Phenotypic Heterogeneity in Coronary Spastic Angina through Multidimensional Risk Profiling: The FUJI-SPASM Study
Background: Coronary spastic angina (CSA) is a functional coronary disorder characterized by transient epicardial constriction in the absence of significant atherosclerosis. Howeve...
Abstract 4370012: Outcomes of Transvenous Lead Extraction in Young Patients
Background: Transvenous lead extraction (TLE) is increasingly necessary for CIED management, especially young patients who are likely to require multiple device revisions over thei...
Abstract 4371282: Utility of a REV-ERB Agonist as a Protective Agent Against Chemotherapy-Induced Heart Failure
Cancer survivors treated with doxorubicin (Dox) are 37% more likely to develop heart failure post-treatment, highlighting the urgent need for adjuvant therapies. REV-ERB, a nuclear receptor essential...
Abstract 4346986: Comparable Efficacy of Intracardiac and Transesophageal Echocardiography in Left Atrial Appendage Closure: Findings from an Umbrella Review
Background: As left atrial appendage closure (LAAC) becomes more widely adopted for stroke prevention in patients with atrial fibrillation, optimizing peri-procedural imaging has g...
Abstract 4370159: In-Hospital Outcomes of Acute Noncardiac Organ Failure among Non-Acute Myocardial Infarction Cardiogenic Shock: A Nationwide Cohort Analysis
Introduction: Noncardiac organ failure is a frequent complication in non–acute myocardial infarction (non-AMI) cardiogenic shock (CS), yet its impact on in-hospital outcomes remain...
Abstract 4344355: Optical Coherence Tomography–Guided Versus Angiography-Guided Percutaneous Coronary Intervention in Patients with Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials
Background: Data regarding clinical outcomes after optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) compared to angiography-guided PCI in patients...
Abstract 4360903: Impact of Early Cardiology Consultation on In-Hospital Outcomes in Heart Failure.
Background: Acute decompensated heart failure (ADHF) is a medical emergency associated with high morbidity and mortality. Specialist cardiology consultation (CC) has been linked to...
Abstract 4360560: Cardiovascular Health and Cardiovascular Disease Risk: Trends and Projections to 2040
Background: Along with the advent of the second century of the American Heart Association, two novel metrics have emerged to advance cardiovascular health: Life’s Essential 8 (LE8)...
Abstract 4371309: Sex, Racial/Ethnic, and Income Disparities in STEMI Outcomes: Differential Resource Utilization in 5 Year National Cohort
Introduction: ST-segment elevation myocardial infarction (STEMI) requires urgent intervention, yet significant disparities in outcomes persist. While sex and racial/ethnic disparit...
Abstract 4369453: Aortic Valve Neocuspidization Using Autologous Insertion Of Pulmonary Sinus <sup>Tm</sup> : A Proof Of Concept
Objectives: We developed and evaluated a novel aortic valve neocuspidization technique using autologous pulmonary sinuses in an ex-vivo porcine model. Human anatomical feasibility...
Abstract 4371060: A Comparative Analysis of Social Demographic and Clinical Factors for Screening for Peripheral Artery Disease in Adult Patients from Primary Care Clinics
Background: Peripheral Artery Disease (PAD) affects over 8.5 million adults in the U.S., contributing to morbidity and mortality. Early detection is critical but often missed, espe...
Abstract 4362545: Demographic and Regional Trends of Mortality in Patients with Cardiovascular diseases and Chronic Renal Failure related mortality in older adults of United Nationwide Analysis (1999-2022)
Background: Cardiovascular diseases (CVD) and chronic renal failure (CRF) represent significant causes of mortality in the United States, particularly among individuals aged 65 and...
Abstract 4350203: From Image to Insight: Precise and fast RV Volumetry using 2D-Echocardiography
Background: Accurate assessment of right ventricular (RV) volume is crucial for monitoring patients with congenital heart defects (CHD). However, due to the RV's complex geometry,...