Circulation
Articles in this Issue
Abstract TH945: The Weight of Stress: Examining the Association Between Perceived Stress and Body Mass Index (BMI) in The EPIPHANY (Equity in Prevention and Progression of Hypertension by Addressing barriers to Nutrition and Physical Activity) Study
Background: Black adults in rural areas have higher obesity prevalence (48.3%), lower socioeconomic status, and decreased access to health services contributors to poor cardiovascu...
Abstract WE451: D3 Creatine Dilution – Assessed Muscle Mass is Associated with Lower Perceived Physical Fatigability Among Older African Caribbean Men
Background: Fatigability, the degree of fatigue experienced in response to activities of standardized intensity and duration, is a well-recognized marker of functional decline, mor...
Abstract TU187: Serum Metabolomic Signature of the EAT-Lancet Diet and Incident Cardiovascular Disease and All-cause Mortality: Evidence from the Atherosclerosis Risk in Communities (ARIC) Study
Backgroud: Greater adherence to the Planetary Health Diet Index (PHDI) is associated with lower risks of incident cardiovascular disease (CVD) and all-cause mortality; however, the...
Abstract TU184: Polygenic Risk Scores That Uncouple Obesity From Cardiometabolic Risk Protect Against Longitudinal CHD and T2D Risk
Body mass index (BMI) defined obesity is an established risk factor for cardiometabolic diseases, yet its cardiometabolic consequence is highly heterogeneous. We recently conducted genome-wide associa...
Abstract 15: Rural-Urban Differences in Accelerometer-Measured Physical Activity Among Older U.S. Adults: Findings from the REGARDS Study
Introduction: Older adults in rural areas face elevated chronic disease risk and greater barriers to physical activity (PA). We determined how PA patterns vary across the rural-urb...
Abstract TH923: Proteomic Signature of the Dietary Approaches to Stop Hypertension (DASH) Diet by Diabetes Status
Introduction: The Dietary Approaches to Stop Hypertension (DASH) diet has recently been shown to improve glycemia in individuals with type 2 diabetes. Yet, the proteomic mechanisms...
Abstract WE553: Discrimination and Calibration of the Pooled Cohort Equation Among Hispanics/Latinos Stratified by Background group and Genetic Ancestry: Insights from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Background: The Pooled Cohort Equation (PCE), a central tool in preventive cardiology, was developed without representation of Hispanic/Latino adults, a diverse and heterogenous gr...
Abstract WE517: Epicardial Fat Predicts Heart Failure in Atrial Fibrillation Through Associations with Cardiac Remodeling
Background: Atrial fibrillation (AF) frequently coexists with cardiometabolic conditions such as diabetes and heart failure (HF), which increase morbidity and mortality. While body...
Abstract WE461: Trends in Hypertension Control Using Traditional and New Guideline-Directed Blood Pressure Control Parameters: Results from the National Health and Nutrition Examination Survey (NHANES), 2011–2020
Background: Hypertension (HTN) is a key modifiable cardiovascular risk factor. The 2025 AHA/ACC blood pressure (BP) guidelines reaffirmed <130/80 mmHg as the new BP treatment ta...
Abstract 09: Healthcare Interactions, Diagnoses, and Service Utilization Preceding Cardiovascular Mortality Associated with Homelessness
Background: Cardiovascular disease (CVD) persists as the leading cause of death among U.S. adults. Persons experiencing homelessness (PEH) face a disproportionate burden with earli...
Abstract MPTH64: High-Intensity Interval Training Provides Greater Gains In Quality of Life Than Moderate-Intensity Continuous Training in Post-Myocardial Infarction Patients: A Systematic Review of Randomized Controlled Trials
Background: Cardiac rehabilitation (CR) is emerging as an essential aspect of secondary prevention in patients recovering from acute myocardial infarction (AMI) or coronary artery...
Abstract MPTU16: Individual-level Social Determinants of Health and High-Risk Behavioral Engagement Among Puerto Rican Young Adults: PR-OUTLOOK Study
Introduction: High-risk behaviors, such as tobacco use, physical inactivity, and excessive alcohol consumption contribute to chronic diseases, including cardiovascular disease and...
Abstract MPTH59: Cumulative Blood Pressure Burden Above Optimal Level and Risk of Cardiovascular Disease in Patients with Diabetes
Introduction: The 2025 AHA/ACC Blood Pressure (BP) Guidelines recommend a systolic BP (SBP) goal of <130 mm Hg, with encouragement to <120 mm Hg, and a diastolic BP (DBP) goa...
Abstract MPTU03: A “numerical autopsy” of out-of-hospital cardiac arrest: reclassifying unknown etiologies from five years of nationwide health data
Background: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue. However, most cases are classified as having “unknown” etiologies, because the majority of pa...
Abstract 08: Land Use Rezoning of a Bronx, New York Neighborhood and Cardiovascular Disease Incidence in Mid-life and Older Adult Patients
Introduction: Land use rezoning policies can spur new investment and revitalization in the area. Such revitalization efforts in low-income areas have been inconsistently linked to...
Abstract TU149: Indoor Environmental Exposures and Pediatric Heart Conditions in US
Background: Indoor environmental exposures such as mold and pesticide use are increasingly recognized as potential contributors to adverse child health outcomes, but their relation...
Abstract TH897: Fatality After Acute Myocardial Infarction in Immigrants Compared to Native Koreans: A Nationwide Population-Based Study
Background: South Korea has been trying to improve early symptom awareness of acute myocardial infarction (AMI) and stroke, focusing primarily on native Koreans. Due to potential g...
Abstract TU155: Health-Related Social Needs and Hypertension Awareness, Treatment, and Control among Community-Dwelling Black Men
Non-Hispanic Black men have the highest hypertension (HTN) prevalence and the lowest awareness, treatment, and control in the U.S. Health-related social needs (HRSNs) refer to social and economic cond...
Abstract TU107: Guideline-Based Pharmacotherapy Eligibility Among Older Adults with Stage I Hypertension
Background: The 2025 AHA/ACC hypertension guideline removes the age ≥ 65 years route to immediate pharmacotherapy in stage I hypertension and introduces a risk-guided approach usin...
Abstract TU254: Global Impact of Tobacco Control Policies on Cardiovascular Mortality: A Lag-Adjusted Fixed-Effects Analysis of 148 Countries (2007–2022)
Background: Tobacco use remains a leading modifiable driver of cardiovascular disease (CVD) worldwide. The WHO MPOWER framework quantifies national tobacco-control strength, yet lo...
Abstract WE508: Ultra Processed Foods (UPF) and Risk of Incident Coronary Heart Disease (CHD) REasons for Geographic and Racial Disparities in Stroke (REGARDS)
Background: Diet plays a critical role in coronary heart disease (CHD) risk, and evidence links intake of ultra-processed foods (UPFs) to increased cardiovascular risk. CHD mortali...
Abstract TH872: Elevated Lipoprotein(a) and Incident Aortic Stenosis Independent of Low-Density Lipoprotein Cholesterol in a Multisystem United States Cohort
Background: Lipoprotein(a) [Lp(a)] has been implicated in the pathogenesis of calcific aortic valve disease through pro-inflammatory and pro-calcific mechanisms. However, large-sca...
Abstract TU233: Achieving Goal Low Density Lipoprotein Cholesterol in Pediatric Patients Treated with Lipid-Lowering Therapy
Background: Randomized clinical trials show short- and medium-term safety and good LDL-C lowering of lipid lowering therapy (LLT) in pediatric patients, with 40-60% of patients rea...
Abstract WE573: Trends in Cardiovascular Disease (CVD) Risk Factors in American Indian Populations: A Phase 7 update from the Strong Heart Family Study (SHFS)
Introduction: CVD is the leading cause of death among American Indians but major CVD risk factors, like hypertension, diabetes, obesity, smoking, and abnormal cholesterol, have not...
Abstract MPTH56: Association of Cognitive Decline with Orthostatic Hypotension among Older Adults: Findings from the Atherosclerosis Risk in Communities Study
Background: Orthostatic hypotension (OH), a blood pressure (BP) dysregulatory condition, is associated with dementia, stroke, and all-cause mortality. OH develops from autonomic im...