Circulation
Articles in this Issue
Abstract TU263: Association of Difficulty Falling Asleep and Sleep Duration with the Risk of Cardiovascular Events in the General Japanese Population: NIPPON DATA 2010
Introduction: Sleep quality could be an important risk factor for cardiovascular disease, beyond the influence of sleep duration. In particular, difficulty falling asleep, a sympto...
Abstract TH957: Performance of Cardiometabolic Polygenic Scores in a high-altitude Peruvian Population
Background: Polygenic scores (PGS) aggregate the effects of multiple genetic variants to estimate disease risk. Limited ancestral diversity in discovery and validation datasets may...
Abstract WE513: Diet Quality and Stage I Hypertension under Contemporary Guidelines: National Trends and Dietary Simulation of Treatment Reclassification
Background: The 2025 AHA/ACC hypertension guideline newly anchors management to PREVENT 10-year risk and calls for a 3-6 month period of nonpharmacologic therapy followed by reasse...
Abstract TU253: Predictors of Language Strength in State Legislation Related to School Nutrition
Introduction: Dietary habits are a major contribution to the risk of developing chronic disease. School-based nutrition programs play a vital role in supporting children’s nutritio...
Abstract TH954: High, even more than low, ankle-brachial index (ABI) associated with elevated risk of incident cardiovascular disease and all-cause mortality: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Background: Low and high ankle-brachial index (ABI) values are associated with increased cardiovascular disease (CVD) risk, yet their prognostic value in Hispanics/Latinos has not...
Abstract TH814: Independent Genetic Effects of <i>GLP1R</i> Locus on Body Mass Index and Type 2 Diabetes
Background: The glucagon-like peptide-1 receptor ( GLP1R ) gene has been implicated in metabolic regulation. GLP1R...
Abstract WE566: Barriers and Facilitators to Post-Stroke Rehabilitation Among Stroke Survivors and Caregivers in India
Introduction: Stroke is the second leading cause of death and third leading cause of disability among non-communicable diseases. Rehabilitation is vital in restoring motor function...
Abstract TU190: Comparison of the Olink and Alamar Paired Antibody-based Plasma Proteomics: The Dallas Heart Study
Introduction: Plasma proteomics provide valuable insights into circulating biomarkers of disease risk associated molecular pathways. However, challenges persist for low abundance p...
Abstract 76: Consistency of Meeting Physical Activity Guidelines and Long-term Risk of Cardiovascular Disease
Background: The long-term consistency of meeting physical activity guidelines may be critical for cardiovascular health, yet its independent contribution beyond total physical acti...
Abstract MPWE27: Weekday Temporal Step Accumulation Patterns and Hypertensive Disorders of Pregnancy
Introduction: Physical Activity (PA) during pregnancy is known to reduce the risk of hypertensive disorders of pregnancy (HDP). However, little is known regarding how daily PA patt...
Abstract WE547: Patient Perspectives of Life’s Essential 8 Cardiovascular Health Questionnaire and Cardiovascular Health Score
Introduction/Background: The American Heart Association’s Life’s Essential 8 (LE8) is a cardiovascular health (CVH) framework assigning scores to eight CVH metrics, inversely assoc...
Abstract TH969: High Left Ventricular Mass on Cardiac Magnetic Resonance Imaging is Associated with Incident Frailty in Community-dwelling Adults
Introduction: Cardiovascular disease (CVD) and frailty share pathophysiology and risk factors. Markers of subclinical CVD on cardiac magnetic resonance imaging (CMR) have been asso...
Abstract TU244: Negative Affective Responsivity is Differentially Related to Postprandial Changes in Pulse Pressure Augmentation Between Hispanic or Latine and non-Hispanic White Young Adults
Latine and Hispanic Americans (LHA) experience poorer cardiometabolic outcomes than their non-Hispanic White (NHW) counterparts, potentially due to differential psychosocial stress exposure. Altered p...
Abstract TU103: Adherence to the Mediterranean diet and some related serum metabolites are strongly associated with epigenetic biomarkers of aging in Mediterranean subjects
Background and aims: The Mediterranean diet (MedDiet) is a healthy dietary pattern that has been consistently associated with reduced cardiovascular disease incidence. Likewise, hi...
Abstract 54: Body Weight, Human Gut Microbiome, Blood Metabolome, and incident Type 2 Diabetes- A Multi-Omics Integration Study
Background: Few prospective human studies have characterized interrelationships between body weight, gut microbiome, plasma metabolome, and incident type 2 diabetes (T2D)....
Abstract TH887: Modifiable Risk Factors for Dementia and Their Association with Cognitive Performance and Brain Structure Among Hispanic/Latino Individuals in Early and Middle Adulthood
Introduction: Few studies have examined the association of modifiable risk factors for dementia with cognitive performance and brain structure in early and middle adulthood, when u...
Abstract TU196: Lipid Catabolism and Cytokine Signaling Show Divergent Associations with 30-year Incidence of Coronary Artery Disease in Type 1 Diabetes
Prior studies of biomarkers for coronary artery disease (CAD) in the high-risk type 1 diabetes (T1D) population focused on candidate proteins but such analyses may miss the complex systemic process un...
Abstract TU174: UPF Intake Patterns in the Context of Overall Diet are Differently Associated with Self-Reported Health Status
Introduction: Excess ultra-processed food (UPF) intake has been consistently associated with adverse health. Yet, UPFs are heterogeneous ranging from possibly beneficial (e.g., who...
Abstract TH941: Cardiovascular Health of First-Time Fathers During Pregnancy: Findings from the Dad Bod Observational Cohort Study
Introduction: Promoting optimal cardiovascular health (CVH) earlier in life is essential for preventing future cardiovascular disease. The transition to fatherhood represents a maj...
Abstract TH911: Association of Stroke with Social Determinants of Health and Race-Gender Demographics
Introduction: Social determinants of health (SDoH) are recognized as key contributors to adverse cardiovascular outcomes. However, the magnitude of the association between stroke a...
Abstract WE433: Prospective Associations of Physical Activity and Sedentary Behaviors on Reduced Cardiovascular Disease Risk in Older Women with Diabetes: The OPACH Study
Background: This study tested the hypothesized significant associations of physical activity (PA) and sedentary behavior (SB) with lower risk of incident CVD among older women with...
Abstract 53: Prediabetes Status Modifies the Effect of a DASH-Patterned Grocery Intervention on Cardiometabolic Risk Including Glycemic Control in Black Adults with High Blood Pressure
Introduction: The Dietary Approaches to Stop Hypertension (DASH) diet was designed for its cardiovascular benefits but emphasizes higher carbohydrates. Its impact on glycemia in ad...
Abstract TH848: Explainable Machine Learning-Based Identification of Clinical and Nutritional Determinants of Cardiovascular Diseases
Background: Cardiovascular diseases (CVDs) remain the leading cause of death globally. Traditional risk models have emphasized adverse clinical factors, yet very few studies jointl...
Abstract TH946: Examining Bi-directional Effects between Mental Health and Physical Activity
Background: Understanding the longitudinal interplay between psychological well-being and health-related behaviours, such as physical activity, is critical for promoting sustainabl...
Abstract WE535: Supine Resting Hemodynamics are Unchanged by Anticipation of Same-day Exercise
Introduction: Previous studies have shown that exercise anticipation may exhibit elevated resting blood pressure values when measured immediately prior to exercise testing. Whether...