Circulation
Articles in this Issue
Abstract TH979: Lipoprotein(a) Across Menopause: Longitudinal Changes in the UK Biobank
Introduction: Menopause may coincide with rising lipoprotein (a) [Lp(a)] levels, a pro-atherogenic, pro-thrombotic, and pro-inflammatory atherosclerotic cardiovascular disease (ASC...
Abstract TH867: Surveillance of Lipids and Glycemia Profiles and their Awareness in the Adult Population: Italian Health Examination survey 2023-2025 - CUORE Project
Introduction: Glycemic and lipid assessment in the population is recommended by the WHO as well as the target to halt the rise of diabetes within 2025 (2010 as baseline). The Itali...
Abstract TU273: Early Life Exposures and Age at Menopause in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study
Background: Younger age at menopause (premature and early menopause) occurs more often in Black women than in White women and is associated with an increased cardiovascular disease...
Abstract TU258: Height Loss Predicts All-Cause and Cardiovascular Disease Mortality among Residents of Evacuation Zones Following the Great East Japan Earthquake: The Fukushima Health Management Survey
Introduction: Major disasters such as the Great East Japan Earthquake and prolonged displacement can exacerbate undernutrition, psychological stress, and limited medical access. Th...
Abstract TH961: Beyond Traditional Risk Factors: A Data-Driven Approach to Coronary Artery Disease (CAD) Prediction
Background: Coronary artery disease (CAD) remains the leading cause of death worldwide, accounting for over 370,000 deaths in the United States in 2022. Traditional tools such as t...
Abstract 61: Association of Cumulative Blood Pressure Elevation During Young Adulthood With Cardiovascular and Kidney Outcomes in Midlife.
Introduction: While non-optimal blood pressure (BP) is the most common modifiable risk factor preceding cardiovascular disease (CVD), the cumulative impact of early-life elevated B...
Abstract TU112: SGLT2 inhibitors Improve Cardiovascular Outcomes in Patients with Transthyretin Amyloid Cardiomyopathy
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve clinical outcomes in cardiovascular-kidney-metabolic diseases, but the high-risk population of patients wit...
Abstract WE548: Greater Cardiovascular Risk Is Associated with Higher Liver Dysfunction: An NHANES Analysis Using FIB-4 and PREVENT Equations
Background: Cardiovascular disease (CVD) and liver dysfunction share metabolic pathways involving systemic inflammation and dysregulation. While evidence suggests liver dysfunction...
Abstract TU121: Life’s Essential-8 Cardiovascular Health Metrics, Carotid Intima-Media Thickness, and Carotid Plaque: A Cross-Sectional Study among Japanese Men
Introduction: The American Heart Association’s new Life’s Essential-8 (LE8) metrics is considered a comprehensive framework for pursuing optimal cardiovascular health (CVH). Howeve...
Abstract TH940: Enhancing Patient Safety Through Health Literacy: A Quantitative Outcomes Study of the P.L.A.N. Counseling Tool in People Experiencing Homelessness
Introduction: Low health literacy is a significant barrier to chronic disease management and patient safety, leading to poor medication adherence and increased adverse events. Thes...
Abstract WE493: Intersections of Social Determinants, Food Insecurity, Diet Quality, and Mental Health in Mortality Risk: Joint and Mediating Effects
Background: Poor nutrition is a major contributor to disease and mortality, and intersects with food insecurity, broader social determinants of health (SDOH), and mental health. Ho...
Abstract WE525: Longitudinal changes in visceral adiposity, glycemic traits, and inflammatory proteomic profiles
Central obesity is related to an elevated risk of type 2 diabetes (T2D) and cardiovascular diseases (CVD), partly through chronic inflammation caused by metabolically active visceral adipose tissue (V...
Abstract TU156: A Single Hypertensive Measurement Independent of an Average of Three Measurements is Associated with a Higher Risk of Cardiovascular Disease
Background: Hypertension (HTN) guidelines recommend averaging up to three blood pressure (BP) measurements. However, it is unclear how to interpret risk for cardiovascular disease...
Abstract MPTH58: The Impact of Postpartum Remote Blood Pressure Monitoring on Hospital Readmission
Introduction: Postpartum hypertension is a leading cause of severe maternal morbidity and mortality. Approximately half of those with hypertensive disorders of pregnancy (chronic h...
Abstract TH844: Beyond the heart: neuropsychiatric factors as leading risk markers for sudden cardiac arrest in the young
Background: Sudden cardiac arrest (SCA) in young adults, with survival rates below 15%, represents a major public health concern. Most cases occur in individuals without identifiab...
Abstract TU270: Sleep Disturbance and Risk of Cardiovascular Disease Hospitalization in Over Two Million Adults: Evidence From a Japanese Health Insurance Claims Database
Introduction: There is increasing evidence that sleep disturbances may lead to adverse cardiovascular disease (CVD) outcomes. Therefore, documenting sleep disturbances at health ch...
Abstract 46: Daily Step Count Is Lower Across Perceived Physical Fatigability Severity Strata in Older Caribbean Men
Background: Perceived physical fatigability (i.e., fatigue experienced in response to activities of standardized intensity and duration) is a sensitive, person-reported outcome mea...
Abstract TU144: The Rising Toll of Environmental Toxins: An Age-, Sex-, and Region-Stratified Analysis of Cardiovascular Disease Attributable to Lead Exposure Across 204 Countries (1990–2023)
Background: Lead exposure (LE) remains a widespread environmental toxin with no known safe threshold and has been increasingly recognized as a modifiable risk factor for cardiovasc...
Abstract WE568: Place of Death for Cerebrovascular Mortality, 2018–2023: Hospice–Forward U.S. Trends From CDC WONDER
Background: Where cerebrovascular deaths occur reflects emergency access, end-of-life preferences, and palliative capacity. Whether hospice’s role changed during and after the pand...
Abstract TH807: A Community Health Worker-led Nutrition-Enhanced Hypertension Management Intervention: Randomized Pilot Feasibility Trial
Background: Diet modification is an AHA/ACC Class 1 recommendation for hypertension management. Few clinical dietary interventions for hypertension exist, particularly in low-incom...
Abstract WE556: Digital Media Exposure and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis
Background: social media, screen time, online gaming, and digital work settings are just a few examples of the rapidly expanding digital media use that has sparked worries about it...
Abstract TH934: Real-World Comparison of Crizanlizumab With or Without Hydroxyurea Versus Usual Care on Vaso-Occlusive Crisis Frequency in Sickle Cell Disease
Introduction: Sickle cell disease causes recurrent vaso-occlusive crises (VOCs) that drive morbidity and healthcare use. Hydroxyurea (HU) is standard therapy, yet many still experi...
Abstract WE501: Unique Stress, Cultural Resources, and Psychological Resilience in Young African American Women: Insights for Effective Intervention and CVD Prevention
Objective: Psychological resilience, defined as one’s self-reported ability to bounce back from stress, is understudied in young African American women (YAAW). Guided by community...
Abstract TH812: Effects of a DASH-style diet on fecal and plasma short-chain fatty acids in adults with type 2 diabetes.
Background: The Dietary Approaches to Stop Hypertension for Diabetes (DASH4D) trial showed that a DASH-style diet vs. typical US comparison diet improved glycemia in adults with ty...
Abstract MPTU20: Ultra-Processed Food Intake, Lipidomics, and Incident Cardiovascular Disease in American Indians: A Longitudinal Study
Background: Ultra-processed food (UPF) consumption has been linked to cardiometabolic risk, but its molecular signatures remain unclear....