Circulation
Articles in this Issue
Abstract 22: Cooking Oil Choice and Cardiometabolic Risk Among Asian Indians: Evidence from the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) National Study
Background: The type of cooking oil used is an under recognized dietary factor influencing cardiometabolic disease in India. Little is known about how commonly used oils relate to...
Abstract TH977: Endometriosis and Early-Onset Cardiovascular Disease: Effect Modification by Systemic Inflammation and Age at Menarche
Introduction: Endometriosis, a chronic gynecological condition, has been increasingly associated with increased cardiovascular disease (CVD) risk. However, the mechanisms underlyin...
Abstract MPTH69: Metabolic Dysfunction-Associated Steatotic Liver Disease Across the Cardiovascular-Kidney-Metabolic Spectrum: Insights from the CARDIA Study
Background: The prevalence and prognostic impact of metabolic dysfunction-associated steatotic liver disease (MASLD), overall and across the cardiovascular-kidney-metabolic (CKM) s...
Abstract TH881: Demographic and Cardiovascular Risk Factors Influence Midlife Cognitive Function: Evidence from the i3C DECADE Study
Introduction: Age, sex, race, and education are known determinants of cognitive performance in traditional neuropsychological testing; however, their impact on novel digital measur...
Abstract TH927: Validity of Ankle-Brachial Index and Other Modalities to Identify Peripheral Artery Disease in the Community
Background: Resting ankle-brachial index (ABI) is the first-line diagnostic test for lower extremity peripheral artery disease (PAD). Previous studies that reported high sensitivit...
Abstract TH839: Barriers to Enrollment and Attendance in Outpatient Cardiac Rehabilitation Access after TAVI in Tennessee
Background: Outpatient cardiac rehabilitation (OCR) is a recognized key component of secondary prevention of cardiovascular disease, particularly after procedures such as transcath...
Abstract TU195: Comparison of Large-Scale Proteomics Platforms: The Dallas Heart Study
Introduction: Large-scale proteomic profiling plays an important role in the identification of novel biomarkers. We compared the performance of three proteomics platforms in a mult...
Abstract TH866: Associations of Plasma Very Long-Chain Saturated Fatty Acids with Cardiovascular Disease Risk are Influenced by Lipid Interactions
Introduction: Very long-chain saturated fatty acids (VLCSFA: C20:0, C22:0, C24:0) may influence cardiometabolic health differently from other, often detrimental, saturated fatty ac...
Abstract 16: Cardiorespiratory Fitness, Coronary Artery Calcium, and Later-Life Dementia: The Cooper Center Longitudinal Study
Introduction: Cardiorespiratory fitness (CRF) and coronary artery calcium (CAC) score, both established cardiovascular risk markers, may be interrelated; however, their individual...
Abstract WE403: Development and Implementation of an Artificial Intelligence-Based Predictive Model for Sudden Cardiac Death by Integrating Personal Health Records and Clinical Data
Background: In Japan, approximately 90,000 individuals die annually from sudden cardiac death (SCD). Predicting SCD using electronic health records (EHRs) from hospitals remains di...
Abstract TU100: Assessment of the Sarcopenia Index for Detecting Sarcopenia in the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Introduction: Sarcopenia is the age-related loss of muscle mass, strength, and function, and is a risk factor for cardiovascular disease, all-cause mortality, and reduced quality o...
Abstract WE536: Causal Effects of Physical Activity and Sedentary Behavior on Stroke Risk: A Systematic Review and Meta-analysis of Mendelian Randomization Studies
Background: Stroke is a major health burden and the second leading cause of death globally, only after ischemic heart disease. While observational studies have elaborated on the ef...
Abstract WE424: Cardiovascular-Kidney-Metabolic Syndrome Across a Decade: Trajectories in Relation to Social Determinants of Health among Middle-Aged and Older Adults in the United States
Background: Cardiovascular-Kidney-Metabolic (CKM) syndrome, a cluster of conditions, including cardiovascular disease, chronic kidney disease, and type 2 diabetes, is classified by...
Abstract WE524: Metabolomic Analysis in Three US Cohorts With 40 Years of Follow-Up Identifies Metabolomic Profiles Reflecting Metabolic States Associated with Long-Term Obesity Trajectory and Its Related Chronic Disease Risk.
Background: Obesity, a leading risk factor for coronary artery disease (CHD) and other chronic diseases, is a multifactorial condition with heterogenous etiologies and comorbidity...
Abstract WE464: Blood Pressure Lowering To Prevent Clinical Dementia: Systematic Review And Meta-Analysis
Background: High blood pressure (BP) is associated with higher dementia or cognitive impairment risk in observational studies. Prior clinical trial meta-analyses suggested BP-lower...
Abstract 28: Relationship between endometriosis and cardiovascular disease: Insights from mediation analyses within the UK Biobank
Background: Endometriosis has been linked to a higher risk of cardiovascular disease, although the mechanisms are not fully understood. It has been suggested that undergoing a hyst...
Abstract MPWE25: Clinical Predictors of Future Cardiovascular Disease at the Initiation of Prenatal Care
Introduction: Identifying cardiovascular disease (CVD) risk in adults under age 50 remains an unmet need. Pregnancy offers a unique opportunity to identify CVD risk given high heal...
Abstract TH931: Investigating the Association Between α <sub>1</sub> -antagonist Use and Symptomatic Lower Extremity Venous Disease
In this study, we tested the hypothesis that α 1 -antagonist use is associated with the onset of lower-extremity (LE) venous disease....
Abstract TH967: Exploring the association between coronary artery calcium score and behavioral and social determinants of subclinical atherosclerosis in an Appalachian population
Background: Coronary artery calcium (CAC) scoring, a noninvasive method for measuring subclinical atherosclerosis, is an early indicator of future cardiovascular events. Although b...
Abstract MPTU11: Prediabetes Progression In Young American Adults: A Pooling Project
Introduction: There is growing clinical concern about increases in prediabetes and type 2 diabetes in young adults. Novel weight-loss medications, e.g., glucagon-like peptide-1-rec...
Abstract TU99: Changes in DNA methylation-based biological aging predict structural and vascular brain damage in older adults: Age, Gene/Environment Susceptibility - Reykjavik Study
Background: DNA methylation (DNAm)-based biological aging (BA) is linked to poor structural and functional brain integrity, but prior studies often had small samples, cross-section...
Abstract 50: Extending the Observational Medical Outcomes Partnership Common Data Model to Harmonize Dietary Exposure Survey Questions Across Studies
Introduction: Numerous dietary assessments and scores in survey format have been used in cardiovascular disease (CVD) research jointly with study participants’ EHR data. While harm...
Abstract TH808: Culturally Tailored Positive Psychological Intervention in a Cluster-Randomized Trial of Blood Pressure Reduction in Spanish-Speaking Hispanics/Latinos with Uncontrolled Hypertension
Introduction: Positive psychological interventions (PPIs) have demonstrated benefits for mental health and health behaviors, but their effects on physiologic cardiovascular outcome...
Abstract TU125: Lessons Learned from Assessing Body Composition in 24-Month-Old Children Using Air Displacement Plethysmography
Background: The pediatric option of BOD POD Body Composition System (COSMED USA) utilizes air displacement plethysmography to provide a fast, non-invasive assessment of body compos...
Abstract TU167: A Culturally Competent Journey in Nutrition Education
Introduction: Nutrition education is a key strategy in combating obesity and heart disease. The purpose of this exploratory study was to implement A Taste of Af...