Circulation
Articles in this Issue
Abstract TU138: Cannabis Legalization and Emerging Adult Risk: A Cross-Sectional Analysis
Introduction: Cannabis use may result in adverse cardiovascular outcomes and, with growing legalization, is emerging as an important cardiovascular risk factor. More than 20% of Am...
Abstract TU203: Leveraging Parks for Physical Activity Promotion and Cardiovascular Health among African American Children: Feasibility, Acceptability, and Preliminary Efficacy of the <i>NatureUplift</i> Pilot Randomized Trial
Introduction: Children remain underrepresented in cardiovascular health (CVH) research, and few studies have tested community-engaged interventions to promote CVH early in life. We...
Abstract 25: Ultra-processed Food Consumption Magnifies Genetic Risk of Obesity: A Gene-Diet Interaction Analysis in the Women's Genome Health Study
Introduction: Ultra-processed Foods (UPFs) are associated with obesity, a key modifiable factor of poor cardiovascular health. Although genetics contributes to the risk of obesity,...
Abstract TU231: Spousal Pregnancy Loss and Paternal Cardiovascular Disease Risk: Evidence from Chinese and U.S. Cohorts
Background: While pregnancy loss has been linked to increased long-term maternal cardiovascular risk, its implications for paternal cardiovascular health remain unclear. This study...
Abstract MPTH78: Large-Scale Proteomic Profiling of Cardiac Dysfunction in Men and Women with and without HIV: The MACS-WIHS Combined Cohort Study (MWCCS)
Background: People with HIV (PWH) exhibit a high risk of heart failure (HF). Immune dysregulation has been implicated, but the pathophysiology remains incompletely understood. Left...
Abstract MPWE39: Pilot Randomized Clinical Trial of Produce Prescription with Dietitian Coaching to Improve DASH Diet Adherence and Diet Quality: THRIVE Food is Medicine Trial
Background: Despite the efficacy of the Dietary Approaches to Stop Hypertension (DASH) diet, adherence remains low due to barriers, including food access, affordability, lack of ta...
Abstract 26: Reproductive Milestones and Cardiovascular Disease Risk Among Postmenopausal Women by Obesity Status in the Women’s Health Initiative (WHI)
Introduction: Early menarche (<12 years), menopause (<40 years), and a short reproductive lifespan (<35 years), have been associated with increased CVD risk. It is unclear...
Abstract WE521: Clinical Obesity: Prevalence, Cardiometabolic Risk, and Response to Lifestyle Intervention
An expert commission proposed novel diagnostic criteria distinguishing between preclinical and clinical obesity, recommending treatment indications for the latter. However, their relative proportions...
Abstract 71: Replacing Sedentary Time by Moderate-to-Vigorous Physical Activity or Sleep on a 24h Period in Early Adolescence Is Associated with Lower Insulin Resistance Five Years Later: Prospective Analysis Within the Project Viva Cohort
Introduction: Physical activity, sedentary time and sleep are determinants of adolescent cardiometabolic health. However, few studies have examined the interrelatedness of these be...
Abstract TU222: Lactation and Maternal Serum Metabolomic Profiles in Relation to Cardiometabolic Disease: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Introduction: Lactation has been associated with improved long-term cardiometabolic health in women, but the underlying mechanisms remain unclear....
Abstract TU217: Self-Reported Environmental Support and Device-Measured Physical Activity During Pregnancy: Evidence from the Pregnancy 24/7 Cohort
Background: Adequate physical activity and limited sedentary time during pregnancy reduce the risk of pregnancy-related complications. This study examined associations between self...
Abstract MPTU02: Wearable Data Sharing Preferences for Research Purposes Among U.S. Adults: From Attribute Development to Interactive Dashboard for Research Study Design Optimization
Background: Consumer wearables such as Fitbit and Apple Watch are increasingly used in health research. Although surveys show high willingness among U.S. adults to share wearable d...
Abstract MPWE28: Metabolomic Pathway Alterations in Serum of Postmenopausal Women with Stroke
Background: Among postmenopausal women, stroke is a major contributor to death and disability, yet the biological pathways influencing risk and outcomes remain largely unknown....
Abstract TU218: Are U.S. Women Meeting Nutritional Guidelines Across Pregnancy? Data from a Multicenter National Cohort
Introduction: Optimal nutrition during pregnancy is essential to support maternal health and fetal development. Although the 2020-2025 US Dietary Guidelines include specific nutrit...
Abstract TU139: Demographic and Regional Burden of Opioid Dependence Disorder in the All of Us Cohort
Background: Opioid dependence disorder is a top row public health concern in the United States. Large electronic health record data from the All of Us Research Program allow measur...
Abstract TU224: Effect of Adverse Childhood Experiences on Blood Pressure Variability, and Depression Among Pregnant Women in Georgia
Background: Maternal health is critical in the U.S., especially in Georgia, with the second-highest maternal mortality rate. Adverse Childhood Experiences (ACEs), including early l...
Abstract WE560: Civic Engagement Disparities among Adults with Cardiovascular Disease in the United States
Background: Civic engagement including voting, volunteering, and participating in public meetings is essential for shaping community priorities and health policy. Individuals with...
Abstract 42: Opportunistic Screening versus Population-Wide for Hypertension: A Microsimulation Study
Background: To massively scale up efforts to diagnose and treat hypertension, different screening strategies have been proposed (population-wide screening campaigns and healthcare...
Abstract TH924: Associations Between a Validated Dietary Approaches to Stop Hypertension (DASH) Screener Score and Cardiovascular Biomarkers in National Health and Nutrition Examination Survey (NHAHES), 2009-2014
Introduction: Despite being recognized as a critical cardiovascular disease (CVD) risk factor, diet is rarely comprehensively measured due to cost and time constraints. A valid too...
Abstract WE519: Association between Dynapenic Obesity and Cardiovascular Outcomes and Mortality: A Systematic Review and Meta-analysis
Background: Dynapenic obesity (DAO) is increasingly recognized as a potential risk factor for cardiovascular (CV) disease. However, its impact on CV events and mortality remains un...
Abstract WE571A: Psychosocial Stressors Linking Perceived Neighborhood Physical Disorder to Stroke Risk Among U.S. Adults
Introduction: Neighborhood disorder, defined as adverse physical features of neighborhoods (e.g., vandalism, vacant houses), has been linked to elevated risks of chronic diseases,...
Abstract TU271: Sleep Duration and Mental Health Among Women: Evidence from the SAFE HEART Study Supporting Life’s Essential 8
Background: Sleep, a key component of the American Heart Association’s Life’s Essential 8 (LE8), influences both cardiovascular and mental health. However, its relationship with st...
Abstract TH803: Depression and Cancer History Interact to Exacerbate Clinical Cardiovascular Disease Burden Within the Cardiometabolic–Kidney Framework Among US Women, 2017–2024 Behavioral Risk Factor Surveillance System
Introduction: Women show a stronger depression-cardiovascular disease (CVD) link yet receive 20% less guideline-directed cardiopreventive care. Using nationally representative data...
Abstract WE405: Atrial Fibrillation and Late Onset Epilepsy: Evidence of Bidirectionality in the Atherosclerosis Risk in Communities Study
Introduction: Atrial fibrillation (AF) and late onset epilepsy (LOE) are common conditions, particularly among older adults. These conditions have several shared risk factors, and...
Abstract TH937: Utilizing Life's Essential 8 for Hypertension Management Among Black Patients at a Federally Qualified Health Center (FQHC)
Introduction: Hypertension (HTN), a leading cause of preventable mortality, disproportionately affects marginalized communities due to persistent healthcare disparities and socioec...