Circulation
Articles in this Issue
Abstract MPTU19: Gut Microbiota, Plasma Hippuric Acid, Fiber Intake, and Cardiometabolic Health in U.S. Populations.
Introduction: Hippuric acid is a gut microbiota-derived metabolite of polyphenols. Few population studies have characterized human gut microbial features related to this metabolite...
Abstract TU246: A Meta-Analytic Review of Blood Pressure Responses to Transcendental Meditation
Background: Hypertension is a public health burden, the most prevalent risk factor for cardiovascular disease. Transcendental meditation (TM) is a promising treatment to reduce blo...
Abstract TH965: Equol-Producing Status and Carotid Plaque and Carotid Intima-Media Thickness in Older Adults
Background: Carotid plaque and carotid intima-media thickness (CIMT) are established subclinical markers of atherosclerosis and predictors of cardiovascular events. Equol, a metabo...
Abstract WE544: Rural Patient Populations Overestimate the Effect of Diet on Common Disease Development
Background: Without proper informational couseling, past studies suggest that patients underestimate the effect of diet in chronic disease progression, specifically in gastrointest...
Abstract 03: Impact of SGLT 2 inhibitors and GLP-1 receptor agonists dual therapy on Cardiovascular Outcomes in patients with Heart Failure with Reduced Ejection Fraction and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Propensity-Matched Cohort
Introduction: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) affects 20–30% of patients with heart failure (HF). Conversely, patients with MASLD have a 1.5-fold h...
Abstract TH913: Serum Metabolomics and the Association between Social Determinants of Health and Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study
Introduction: Adverse social determinants of health (SDOH) are associated with greater heart failure (HF) risk, but data regarding underlying biologic mechanisms are limited....
Abstract 44: Symptoms Associated with Early Adverse Echocardiographic Changes in Community-based Cohort in Tobago
Introduction: Transthoracic echocardiography (TTE) is often part of the cardiac evaluation of patient-reported symptoms. Guidelines for obtaining TTE assume its ready availability,...
Abstract WE576: Acute Myocardial Infarction Risk Following COVID-19 Infection and Vaccination in the United States
Introduction: The relationship between COVID-19 infection, COVID-19 vaccination, and myocardial infarction (MI) remains unclear. Characterizing these associations would benefit bot...
Abstract TH906: Design of the HerStory First Study: A Step Toward Understanding Stress, Resilience, and Diet Quality for Culturally Restorative CVD Prevention in Young African American Women
Purpose: High stress contributes to poor diet quality, a key driver of cardiovascular disease (CVD) risk among young African American women (YAAW). Few studies examine psychologica...
Abstract TU249: Associations Between Healthy Eating Efficacy, Stress Eating and BMI Among Puerto Ricans in Puerto Rico and New York
Background: Obesity remains a public health problem for Puerto Ricans in the mainland US and on the island, influenced by suboptimal diet quality and high stress exposure. The Theo...
Abstract TH873: Plasma Proteins Underlying Changes In Triglyceride Metabolism With Exercise Training
Introduction: Angiopoietin like proteins (ANGPTL) 3, 4, and 8 and their complexes (ANGPTL 3/8 and 4/8) are established inhibitors of lipoprotein lipase (LPL), all of which regulate...
Abstract TU280: Endometriosis subtypes and risk of type 2 diabetes: advancing research in cardiovascular health and endometriosis study (ARCHES) retrospective cohort study
Endometriosis is a chronic inflammatory condition that affects ~11% of reproductive-aged women and is characterized by growth of endometrial-like tissue outside the uterus. Chronic inflammation contri...
Abstract WE567: Population Attributable Fractions of Prognostic Factors Associated with Long-Term Risk of Stroke After Transient Ischemic Attack or Minor Stroke: Systematic Review and Meta-Analysis
Introduction: Patients who have had a transient ischemic attack (TIA) or minor stroke have an increased of risk of stroke for at least the next 10 years. Identifying key prognostic...
Abstract WE401: Sex Disparities in Accuracy of Physician-Reported Versus Computed CHA <sub>2</sub> DS <sub>2</sub> -VASc Scores in the Get With The Guidelines–AFIB Registry
Introduction: The CHA 2 DS 2 -VASc score is a widely used tool for stroke risk stratification in atr...
Abstract 02: Systemic Inflammation and Traditional Cardiovascular-Kidney-Metabolic Risk Mediate the Association Between Social Determinants of Health and Incident Heart Failure: Insights from A Multi-Ethnic Cohort
Background: Adverse social determinants of health (SDOH) are strongly associated with incident heart failure (HF), yet the associated biological mechanisms remain poorly defined. W...
Abstract WE434: Higher Gestational Weight Gain Is Associated With A Lower Risk Of Incident Diabetes
Objective: To investigate the association between gestational weight gain (GWG) and risk of future diabetes (DM). Methods:...
Abstract WE436: Identifying the Clinical Threshold of C-Reactive Protein-Triglyceride Glucose Index for Risk Stratification of Diabetes
Introduction: C-reactive protein-triglyceride glucose index (CTI) is a novel composite biomarker for type 2 diabetes mellitus. However, its clinical threshold for diabetes across d...
Abstract TU185: Life’s Essential 8 Protection Against Heart Failure: Metabolomic Insights from the REGARDS Study
Background: Heart failure (HF) is a leading cause of morbidity and mortality. Modifiable health behaviors and factors influence HF development, but pathways linking cardiovascular...
Abstract TU236: Cumulative Cardiometabolic Risk Increases with A1C Even at Subtherapeutic A1C Levels (5.0% to 5.7%)
Background: Current guidelines link elevated hemoglobin A1C above 5.7% with increased cardiometabolic risk; lipid profile, hyperglycemia, and vascular inflammation all serve as key...
Abstract TH880: Feasibility and Acceptability of Fitness Testing at the Minnesota State Fair
Introduction: Wearable technology paired with mobile device applications can provide a convenient, low-barrier method to investigate individual fitness and evaluate cardiovascular...
Abstract TU111: Advanced Peripheral Neuropathy is Associated with Death in Older Adults
Objectives: Peripheral neuropathy (PN) is common in older adults, even in the absence of diabetes. The association of PN with mortality in older adults is poorly characterized. We...
Abstract TU183: Genome-wide association study identified novel genes involved in transporting and metabolizing blood per- and polyfluroalkyl substances
Introduction: Per- and polyfluroalkyl substances (PFAS) are persistent environmental pollutants known as “forever chemicals” that bioaccumulate and cause adverse health effects. Th...
Abstract 30: Gestational weight gain, post-partum weight retention, and women’s mid-life cardiovascular health in Project Viva
Background: Inadequate or excessive gestational weight gain (GWG) is associated with adverse pregnancy outcomes. Less is known about how GWG and post-partum weight retention impact...
Abstract TU136: Quantifying the Rising Burden of Heart Failure Due to Cocaine Use in High-Income Countries: A 34-Year Global Perspective
Background: Cocaine use disorder (CUD) represents a significant, yet often underappreciated, public health challenge in high-income countries (HIC), contributing to substantial car...
Abstract WE499: Social Determinants and Accumulation of Cardiometabolic Risk Factors in a Community Cohort: An Inverse Probability of Treatment Weighting Analysis
Introduction: The co-occurrence of cardiometabolic risk factors (CMRFs) is strongly associated with all-cause mortality and incident disability. Although social determinants of hea...