Circulation
Articles in this Issue
Abstract 4360971: Where Is My Valve? Three-Decade Survival for Tricuspid Valvectomy Without Valve Replacement Following Infective Endocarditis
Background: Amid the opioid pandemic, rising intravenous drug use (IVDU) has markedly increased the incidence of tricuspid valve endocarditis (TVE), a serious complication. While l...
Abstract 4344696: A nationwide survey of the association between the incidence of fatal ventricular arrhythmias and meteorological conditions in Japan
Background: The association between weather and incidence of fatal ventricular arrhythmia (FVA) has been investigated in small-scale studies, primarily involving patients with impl...
Abstract 4366900: Phenotyping Cardiac Surgery Patients Using Retrieval-Augmented Large Language Models
Introduction: Large Language Models (LLMs) are powerful tools for text extraction, but their tendency to hallucinate limits their reliability in clinical domains. We present a nove...
Abstract 4361084: GLP-1 Receptor Agonists in Non-Diabetic Obese Adults: A Retrospective Cohort Study of Cardiovascular and Arrhythmia Outcomes
Background: GLP-1 receptor agonists (GLP-1 RAs) improve cardiovascular outcomes in patients with type 2 diabetes, but their effects in obese adults without diabetes remain unclear....
Abstract 4372907: A Rare Case of Idiopathic Ventricular Fibrillation Triggered by Short-Coupled PVCs from the Apical Free Wall of the Right Ventricle
Introduction: Idiopathic ventricular fibrillation (IVF) refers to VF occurring in the absence of structural heart disease or inherited arrhythmia syndromes such as Brugada, catecho...
Abstract 4370712: Long-Term Cardiovascular Risks Associated with Arrhythmias During Pregnancy
Introduction: The incidence of arrhythmias during pregnancy and maternal mortality rates are rising. While arrhythmia risk is elevated during pregnancy and most cases are considere...
Abstract 4369723: Rate vs Rhythm Control in Elderly Patients with Atrial Fibrillation: A Real-World Comparative Effectiveness Study
Background: Atrial fibrillation (AF) is a common arrhythmia in the elderly, with significant implications for mortality, thromboembolism, and bleeding. While both rate and rhythm c...
Abstract 4362466: Trends in the Prevalence and Implementation of Bystander CPR in South Asia: a Systematic Review
Introduction: Out-of-hospital cardiac arrest (OHCA) is a critical public health concern. Effective and timely cardio-pulmonary resuscitation (CPR) is crucial to survival. Our revie...
Abstract 4348468: Tumor Endothelial Marker 1 Enhances Atrial Inflammation and Promotes Atrial Fibrosis in Atrial Fibrillation
Background: Atrial fibrosis induces atrial fibrillation (AF) and increases the risk of stroke. In our previous study, we demonstrated that tumor endothelial marker 1 (TEM1/CD248),...
Abstract 4370517: Comparative Efficacy of Limus-, and Paclitaxel-Coated Balloons for the Treatment of In-Stent Restenosis: A Pairwise and Network Meta-Analysis of Randomized Controlled Trials
Background: Drug-coated balloon angioplasty is an established treatment strategy for coronary in-stent restenosis (ISR). While paclitaxel-coated balloons (PCB) have been studied mo...
Abstract 4359127: Cardiovascular Outcomes Following Autoimmune Myocarditis: A Propensity Matched Analysis of SLE, SSc, and Overlap Syndromes
Systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) are auto-immunological disorders with recognized cardiovascular involvement, such as myocarditis. Although myocarditis is an uncommon ev...
Abstract 4365241: Impact of Prosthesis Deformation on Long-Term Outcomes After Balloon-Expandable Transcatheter Aortic Valve Replacement
Background: Transcatheter aortic valve replacement (TAVR) is a well-established therapy for severe aortic stenosis. However, suboptimal prosthesis deployment—such as under-expansio...
Abstract 4370403: Forecasting Mortality Associated with Obstructive Sleep Apnea and Sudden Cardiac Death Among Older Adults in the U.S. (1999–2035) Using Machine Learning Models.
Background: Obstructive sleep apnea (OSA) is an established trigger for sudden cardiac death (SCD), yet national mortality patterns and forward-looking risk remain incompletely def...
Abstract 4363382: Increased Inflation-Adjusted Medicare Reimbursement for Cardiac Electrophysiology Procedures from 2013 to 2022
Introduction: Medicare is the largest health care payer in the U.S., and private-payer reimbursement is often influenced by Medicare rates. Thus, trends in Medicare reimbursement h...
Abstract 4368187: Mitral Valve Ellipticity and Functional Recovery After M-TEER: AP/LM Ratio as a Marker of Symptomatic Improvement
Background: Mitral regurgitation (MR) remains a significant cause of morbidity, and MitraClip transcatheter edge-to-edge repair (M-TEER) is an effective treatment for symptomatic s...
Abstract 4357668: Post-Pandemic Surge in Cardiovascular Mortality Among Patients With Thyroid Disease and the Eminent Role of Hypothyroidism: A CDC WONDER Analysis 1999–2023
Introduction: Thyroid disorders are strongly associated with cardiovascular diseases (CVD) due to the wide ranging effects of thyroid hormones on the cardiovascular system. A signi...
Abstract 4366071: Therapeutic Targeting of fibrosis With ANTXR1 Neutralizing Antibodies Improves Cardiac Function in Heart Disease
Background: Fibrosis is a hallmark of heart disease, yet direct antifibrotic therapies remain limited. We identified ANTXR1, a master regulator of fibrosis, overexpressed in diseas...
Abstract 4359950: Challenging Case: Acute Type A Aortic Dissection with Multi-Organ Malperfusion
Case Description: A 57-year-old male with hypertension and obesity presented with acute, severe chest pain. He developed a cold, numb right leg with motor deficits. He was hypotens...
Abstract Sat208: Mechanisms of Central Blood Flow Changes due to Limb Compression during CPR: A Lumped-Parameter Model Approach
Background: Limb compression is commonly used in medicine to address many physiological and pathological conditions. Limb compression is also proposed as a supplement to cardiopulm...
Abstract 4337591: Hyperglycemia and the Longitudinal Progression of Carotid Artery Stiffness Mechanisms: The Multi-Ethnic Study of Atherosclerosis
Background: Total pulse wave velocity (PWV) can be subdivided into two mechanisms: load-dependent PWV due to the distending effect of blood pressure and structural PWV due to arter...
Abstract 4364028: Real-World Outcomes of Tirzepatide Versus GLP-1 Receptor Agonists in Patients with Type 2 Diabetes and Peripheral Arterial Disease
Introduction: Tirzepatide has demonstrated superior glycemic and cardiovascular benefits compared to traditional GLP-1 receptor agonists (GLP-1 RAs) in patients with type 2 diabete...
Abstract 4335923: Added Value of Clinical Data Over Claims Data in Controlling for Confounding by Indication: A Case Example Assessing the Effectiveness of Community-Based Rehabilitation Therapy After Stroke
Background: Observational studies that examine the comparative effectiveness of healthcare services often face challenges in controlling for confounding by indication. This study e...
Abstract 4368459: Temporal Dynamics of Atrial Fibrillation Susceptibility Revealed by Beat-to-Beat Correlations During Sinus Rhythm
Background: Atrial fibrillation (AF) is a common cardiac arrhythmia associated with elevated risks of stroke and heart failure. Although current wearables can detect AF episodes, t...
Abstract Sun1205: Transcutaneous Pacing in the Prehospital Setting – Challenges, Limitations and Opportunities for Improvement
Introduction: Transcutaneous pacing (TCP) is an emergent procedure used in the prehospital setting to treat hemodynamically unstable bradycardia. Prior studies have questioned the...
Abstract 4370082: Machine Learning to Identify Vasoplegia without a Pulmonary Artery Catheter using the Resistance Flow Ratio
Introduction: Postoperative vasoplegia is a complex syndrome, with traditional definitions unable to differentiate isolated vascular dysfunction and mixed cardiogenic-vasoplegic st...